Dr Daniel J. Guerra

Authentic Biochemistry

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Dr Daniel J. Guerra

Episodes

Immune Cell Biochemistry II. B-lymphocyte partially silenced X-chromosome -specific amplification of idiotypic (nc) L-RNA translation products and autoimmunity in women. DJGPhD.19.6.24 19.06.2024 55:19

References Nucleic Acids Res. 2022 Jan 7; 50(D1): D413–D420 Cancers (Basel). 2019 May; 11(5): 678 Oncogene 2017. volume 36: 5593–5608 NAR Cancer. 2024 Jun; 6(2): zcae023. Cell. 2021 Apr 1; 184(7):1790–1803.e17 Nature Immunology 2018. volume 19: 871–884 Pisendel, JG. 1735. Violin Concerto in D major, https://youtu.be/eRVueayvMIk?si=Nitfg70Kwdmo7Xt7 Hayward, J. 1969. "Never Comes the Day"...

Immune Cell Biochemistry. B cells C.12. Epigenetic Regulation. Dr Daniel. J. Guerra.17.6.24.Authentic Biochemistry Podcast 17.06.2024 43:41

References Cell. 2021 Apr 1; 184(7):1790–1803.e17. NAR Cancer. 2024 Jun; 6(2):zcae023. Peretti, Creatore, and Weiss. 1961. "Cant Help Falling in Love". Elvis Presley. https://youtu.be/O-aavAlSYgc?si=yEHWfI2Ny-zvQLnK Lennon-McCartney. 1965. "Wait" Rubber Soul lp. https://youtu.be/qJngWval8Bc?si=CRTQilYzdVZxAtSe Mozart. WA .1788. Divertimento in E Major. K.563. https://youtu.be/E...

Immune Cell Biochemistry. Bcell Electron transport control via calcium mobilization after BCR activation. DJGPhD. 14.6.24. Authentic biochemistry Podcast 14.06.2024 49:00

References Guerra, Daniel J. 2024. Electron transport chain lectures Nature Immunology 2018. volume 19: 871–884 Leach, D. (Allman Brothers Band) 1971. Live at Fillmore East https://youtu.be/w9ZubobGMLs?si=30X6auZQPzrhcB4O

Immune Cell Biochemistry.c.10 Primer on Mitochondrial Bioenergetics I. DJGPhD.13.6.24 14.06.2024 53:51

References Guerra, Daniel J. 2024. Bioenergetics lectures Hunter, R. 1975. "Cruel White Water" https://youtu.be/T-oBD3F74Nk?si=_b3ksQfgbaUEqHA8 Beethoven, LV. 1808. Symphony No. 6 in F, Op. 68 https://youtu.be/xWDIwsfgQnE?si=-vFCnYfdtpivpLnt

Immune Cell biochemistry. BCR activation results in mitochondrial alteration in ETC and OXPHOS. DJGPhD. 12June24 Authentic Biochemistry. 12.06.2024 54:57

References Biophys Res Commun. 2024 Mar 12:700:149598. Eur J Pharmacol.2002 May 17;443(1-3):189-96 Nature Immunology2018 volume 19, 871–884 Mozart, WA 1785. C Major String Quartet 19. K 465 (The Dissonance" https://youtu.be/f3oK4XVMARs?si=xjTTKrC0OL-V1xkX

Immune Cell Biochemistry II. B cells. Two-component B cell activation requires Tfh and/or TLR9 signaling to mediate glucose metabolism for bioenergetic demands. DJGPhD. 10June24 11.06.2024 52:08

References Nature Immunology 2018. volume 19, pages:871–884 Jon Anderson , Chris Squire , and Bill Bruford 1971. "Heart of the Sunrise". Yes. https://youtu.be/0vNcgL9Fi4w?si=DkXqwHwIEuQcTiMt

Immune Cell Biochemistry B lymphocyte c.7 03.06.2024 42:12

References MAbs. 2022; 14(1): 2107971 Commun Biol. 2022; 5: 1292

Immune Cell Biochemistry II.B lymphocyte VDJ recombination is controlled by multiple methyltransferase mechanisms. Dr Daniel J. Guerra. 01June2024.Authentic Biochemistry. 02.06.2024 43:02

References Guerra, DJ. 2024. ImmunoBiochemistry lectures. Commun Biol. 2022; 5: 1292. ACS Chem. Biol. 2017, 12, 4, 958–968 Telemann, GP., 1750. Sonata in D major, TWV 44:1 https://youtu.be/xx8ooc-s7OQ?si=1vAKmdcLroNISa-P Vivaldi, A., 1708. - Gloria (RV 589) https://youtu.be/2eWjQOdYzMQ?si=hYSOqRuXkYUA8ATl

Immune Cell Biochemistry II. B cells The Methyltransferase regulation of RAG 2. Dr Daniel J. Guerra. 29May24. Authentic Biochemistry Podcast 30.05.2024 46:23

References Guerra, DJ. ImmunoBiochemistry lectures 2024. ACS Chem. Biol. 2017, 12, 4, 958–968 Genome Biol. 2005; 6(8): 227 Manfredini, FO. 1718. 12 Concerti Grossi | Op. 3 https://youtu.be/4t-E3wlMkDQ?si=GX0GCLUm48J4V8OY

Immune Cell Biochemistry II. B Cell Event Ontology. 28May24. Authentic Biochemistry Podcast. Dr Daniel J. Guerra 29.05.2024 53:05

References ACS Chem. Biol. 2017, 12, 4, 958–968 Nat Rev Immunol. 2016 Apr; 16(4): 234–246 Guerra, DJ. 2024. Immuno-Biochemistry Lectures Vivaldi, A. 1705. Trio Sonata in D minor, RV 63 https://youtu.be/kPpaeW3DObU?si=nfJmUWlmiK8BZXxD Albinoni , T. 1708. Adagio in G Minor https://youtu.be/z6WOfH2kV00?si=Mf7_6JwuLETu7YEC Scarlotti, D. 1720. Fandango in D Minor https://youtu.be/QQbW75y3P9g?si=MODaHGM...

Immune Cell Biochemistry II. Authentic Biochemistry Podcast. B cell Biochemistry c4. Dr Daniel J. Guerra 27.5.24. 27.05.2024 40:55

References Guerra, DJ. 2024. Immunology Lectures (archives). Pisendel, JG. 1720. : Concerto in E-flat major or Violin, Strings & B.c Jun P I.3 https://youtu.be/SZI2IgOOSPU?si=8xNIyvzxPnkV2zlK Biber, HI. 1676. Passacaglia. G- minor, C.105 https://youtu.be/sgcR183f8gA?si=vYnlxQJDq8LgG_B4

Authentic Biochemistry Podcast. B-Cell Membrane Biochemistry.c.3. Dr. Daniel J. Guerra. 26.5.24 26.05.2024 44:26

References Cancer Science June 2014. 105(9) Acc Chem Res. 2021 May 4;54(9):2110-2120. Nat Immunol. 2022 Jan; 23(1): 99–108. . Bach, JS. 1704.Toccata and Fugue in D minor BWV 565 https://youtu.be/erXG9vnN-GI?si=o6YlpjXM2dRLpyZQ Leach, D. 1965"Catch the Wind" https://youtu.be/J8hjEYTpwE8?si=XeWU1HSy6CGBlEeT

Authentic Biochemistry Podcast. B Cell Membrane Biochemistry.c.2.Dr. Daniel J. Guerra. 25.5.24 26.05.2024 29:53

References Cellular & Molecular Immunology. 2018. volume 15, pages 676–684. Stem Cells Int. 2020: 1047896. Published online Jul 8 Cancer Science. 2014. June.105(9)

Immune Cell Biochemistry II. B Cell Membranes. Introductory Lecture. Dr Daniel J. Guerra. 22May24 Authentic Biochemistry. 23.05.2024 1:00:21

References Nat Commun. 2022; 13: 5371 Schubert, F. 1822.Symphony No. 8 in B Minor "Unfinished," D. 759 https://youtu.be/3tisvEpblig?si=WLsVj4R6gedi7-_a

Authentic Biochemistry Podcast Philosophical Interlude. The Epistemological concurrence of biochemical research with dialectical event ontology. Dr Dan Guerra 20.5.24. 20.05.2024 46:16

References Guerra, DJ. 2019-2024. Previous public lectures and podcasts. Bach, JS. 1721 Brandenburg Concerto No. 2 in F major, BWV 1047 https://youtu.be/3HSRIDtwsfM?si=AA-KdJF2Hyq8RlrE

T cell Membrane Biochemistry. FINE c.25. 18 May 2024.Authentic Biochemistry Podcast.Dr Daniel J. Guerra 18.05.2024 29:55

References Nature 2024.volume 629, pages 417–425 Front. Immunol., 26 April 2019 Sec. NK and Innate Lymphoid Cell Biology. Nature Communications 2020.volume 11. Article 2437 Scientific Reports 2018. volume 8.Article 8700 Int J Mol Sci. 2020 Sep; 21(18): 6497 Hunter-Garcia& Lesh,P. 1969. "Cumberland Blues" On [Workingman's Dead lp.] https://youtu.be/xosZDm01ffc?si=fydGeAchCEAK_5vZ...

T Cell Membrane Biochemistry Fine C24. Endometrial Cancer NK cells:a biochemical pseudoparadox revealing event ontology dialectics. Dr Daniel J. Guerra. 17.5.24 17.05.2024 30:00

References Nature Communications 2020. volume 11, Article:2437 Scientific Reports. 2018. volume 8, Article 8700 Front. Immunol., 26 April 2019 Sec. NK and Innate Lymphoid Cell Biology

Authentic Biochemistry Podcast. T cell Membrane Lipid Biochemistry c.23 Fine I. 15.5.24. Dr. Daniel J. Guerra 15.05.2024 58:28

References Biol Sex Diff. 2021.12:64 Nature 2024. volume 629, pages 417–425 Int. J. Mol. Sci. 2019, 20(3), 646 Front. Immunol.2109. 09 October Sec. Cancer Immunity and Immunotherapy. Volume 10 Schubert, F. 1814-15. Symphonie 2. in B♭ major, D. 125 https://youtu.be/-26Gt4rGaQA?si=_C7MXMG-0piT_4eV Donovan.1968 "Lalena" https://youtu.be/1kA3nZwGHHA?si=f9GFhezzQcOcHapc Dylan, R.1965. "M...

Immune Cell Biochemistry. T cell Membranes Coda VII. C.22 Dr Daniel J. Guerra. Authentic Biochemistry 13.5.24 14.05.2024 46:54

Cancers (Basel). 2023 Nov; 15(21): 5177 GUERRA, DANIEL J.(2022) CYTOEPIGENETICS: DIALECTICAL REVIEW OF A SUBCELLULAR ENDO-MEMBRANOUS COORDINATION OF GENE EXPRESSION AND CELLULAR FATE. Journal of Disease and Global Health, 15 (3). pp. 22-47. ISSN 2454-1842 McCartney-Lennon. 1968 "Martha My Dear." https://youtu.be/RXawa90YU2s?si=_CgaG0yOdbpcflYr

Immune Cell Biochemistry. T cell Membranes. Coda VI. c.21 Methylation Specific Treg differentiation I. 11May24. DJGPhD Authentic Biochemistry Podcast 11.05.2024 36:36

References Acta Pharmacol Sin. 2019 Aug;40(8): 1076–1084 Nucleus. 2022; 13(1): 236–276. Cancers (Basel). 2023 Nov; 15(21): 5177 Dylan, R. 1965 "Like a Rolling Stone" https://youtu.be/IwOfCgkyEj0?si=1vnIW2vqfsg-9MGp Dvorak, A. 1893. Symphony 9 in E minor. Op.95.B178. "From the New World" https://youtu.be/jOofzffyDSA?si=LiM8g7l487jmD22J

Immune Cell Biochemistry.Tcell Membranes. Coda V. C.20 09.05.2024 30:00

References Cancers (Basel). 2023 Nov; 15(21): 5177 Front Oncol. 2021; 11: 750789

Immune Cell Biochemistry I. T cell Membrane Biochemistry. CODA-IV. C.19. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra . 07May24 08.05.2024 30:00

References Cancers (Basel). 2023 Nov; 15(21): 5177. Cancer Discov. 2022 Mar 1; 12(3): 856–871 Gastroenterology. 2023 Feb;164(2): 256–271.e10. Jagger-Richards 1966. "Ruby Tuesday" [Between the Buttons, lp.) Rolling Stones. https://youtu.be/mAyj9q2quYc?si=fv07ARFvr0P2hEAs Schubert, F. 1816. Symphony No. 5 in B♭ major, D. 485. https://youtu.be/OHkot1TmvZU?si=bW0qNDjiAcqJzzvd

Immune Cell Biochemistry I. T Cell Membranes CoDA3/C.18 Authentic Biochemistry Dr. Daniel J. Guerra 06MAY24 07.05.2024 29:43

References Gastroenterology. 2023 Feb; 164(2): 256–271.e10. Ada R. Habershon, and Charles H. Gabriel. 1907. "Will the Circle Be Unbroken" Performed by the Carter Family incl. Johnny Cash. https://youtu.be/JLFbUbmH7To?si=rLPSkV-mHYq3Aodf Mozart, WA. 1783. Mass in C Minor K. 427. https://youtu.be/KsiP4-mCnQ0?si=XoNwMiTO1JK5jPOK

Immune Cell Biochemistry I. T Cell Membranes c.17 Authentic Biochemistry Dr. Daniel J. Guerra 05MAY24 05.05.2024 29:53

References The Journal of Biological Chemistry2018 293, 19001-19011 Cell Death & Disease volume 10, Article number: 315 Experimental & Molecular Medicine 2019. volume 51, Article number: 80. Trends in Immunology. 2017. REVIEW| VOL. 38,Issue 4, P287-297, April 01. Gastroenterology. 2023 Feb; 164(2): 256–271.e10 Squire/ Anderson. 1971. "The South Side of the Sky. on [ Yes -Fragile; lp]...

Immune Cell Biochemistry I. T cell Membrane Biochemistry.CODA 1.Authentic biochemistry Podcast.Dr. Daniel J. Guerra 04.05.2024 29:38

References Gastroenterology. 2023 Feb;164(2): 256–271.e10. The Journal of Biological Chemistry 2018 293, 19001-19011 Leitch, D. 1965 "Catch the Wind" https://youtu.be/J8hjEYTpwE8?si=VfSaLDcP5JxzzP-p Hendrix, J. 1967. "The Wind Cries Mary" https://youtu.be/ARO2vbGFLJM?si=_IIEFN0BOEy6DfqW Bach, JS. 1717. Partita in D Minor, BWV 1004 https://youtu.be/qtyTaE7LvVs?si=q7Xe7rnzDBbEx-...