Dr Daniel J. Guerra

Authentic Biochemistry

Science EN ↓ 1250 episodes

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Dr Daniel J. Guerra

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Science

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Latest episode

Jul 10, 2026

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Episodes

Authentic Biochemistry Podcast. Sphingolipids and Alzheimer’s Disease c.4 [09AUGUST24] Dr Daniel J. Guerra 10.08.2024

References Front. Cell Dev. Biol.2019. 15 August Nat Rev Methods Primers. 2021. 1:30. Chemical Reviews. 2021.Vol 121/Issue 12 RSC Adv. , 2024, 14 , 7383-7413 Lennon/McCartney. 1970 "Let it Be https://youtu.be/QDYfEBY9NM4?si=b6-yGPS63sh8fEtC Lamm, R.1972. "While the City Sleeps" [Chicago V.lp] https://youtu.be/qCrgrGsBlr0?si=OSzuavyf40aEDn-r Mozart WA . 1791.Requiem in D minor K.626...

Sphingolipids and AD. c.3. 07Sept 24.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra 08.08.2024

References Pharmaceutical Research. 2018, March. 35:49 J. Lipid Research. 2018 Apr;59(4):596-606. J Biol Chem. 2016 Jan 22;291(4):1957-73 Front. Cell Dev. Biol. 2019. 15 August Nat Rev Methods Primers. 2021. 1:30 Hunter, R. 1974. "It Must Have Been the Roses" Grateful Dead. https://youtu.be/OhFGxZZpdls?si=fWanXYQv3iJzaZKw Dawson, J. 1971."Last Lonely Eagle" NRPS. https://youtu....

Authentic Biochemistry Podcast . Alzheimer's Disease involves intercellular trafficking of A-beta to the microglia via ceramide stereoisomer specified exosomal transport. c.2. DJGPhD.05Sept24 05.08.2024

References FASEB J .2008. 22:2541-2551 Nat Commun. 2023 Jul 7;14(1):4029. Seminars in Cell & Developmental Biology.2015. Volume 40, April : 115-126 CHIRALITY. 2023. Volume35, Issue9 September:577-585 Lake, G . 1972. "From theBeginning". Trilogy.lp ELP. Begihttps://open.spotify.com/track/1rw12PalmC8IDoygHT3fm1?si=535ae4023d064b16 Telemann, GP. 1720-1740. Various Concertos. https://ope...

Authentic Biochemistry Podcast. “Scientism non fengo” Dr Daniel J. Guerra 02August24 03.08.2024

References Guerra, DJ. 2024. unpublished Sarasate, P.de, 1881. The Carmen Fantasy, Op. 25. https://youtu.be/sYh0fnhKJEo?si=uRDSfFyNgI2o_fNs Anderson,Squire, Bruford,Wakeman. 1971."Heart of the Sunrise" Yes, [Fragile,lp.] https://youtu.be/0vNcgL9Fi4w?si=szH6TVaeyHy_vc2D

Authentic BiochemistryPodcast. Sphingolipid Involvement in AD. c.1. 01August 2024. Dr Daniel J. Guerra 02.08.2024

References Chirality. 2023. Volume35, Issue9 September Pages 577-585. J. Lipid Res. 2018 59:(3) 488-506. JME 2017. -16-0182 V.58.Issue1. r59-71 Pharmaceutical Research 2018, March.35:49 Barber, S. 1967. Agnus Dei https://youtu.be/0LYnNEALm6o?si=M0Y7qsDRgDznmEOI Scarlotti, D. 1720-1740. Various Sonatas. https://youtu.be/X-JaVGYG2i8?si=9s6RXDgTkNFsJEwp

Photosynthesis. IV. Authentic Biochemistry Podcast. Dr Daniel J. Guerra.31.7.24 01.08.2024

References Guerra, DJ 2024. Lecture material Anderson and Howe 1972. "Close to the Edge" Yes. https://youtu.be/51oPKLSuyQY?si=p1MBzMqcJ8QHpAb-

Photosynthesis III. Midsummer. Authentic Biochemistry Podcast.DJGPhD.29.7.24 30.07.2024

References Guerra, DJ. .2024. Lectures series notes Phys. Chem. Chem. Phys. 2020.22.7912-7934 Biber,HF. 1674. Rosenkranz Sonaten. The Mystery SonatasI https://youtu.be/Mq-SrUZUluU?si=um9GDZWWmw52uRUX Baker&Taylor. 1968 "Those Were The Days" On Wheels of Fire; lp CREAM. https://youtu.be/zofyj090Exw?si=Qy62A2xKC3YUytEb

Authentic Biochemistry Midsummer Lecture Series. Plant Biochemistry Interlude II. Chloroplast Lipids and Photosynthesis. 27.7.24. 28.07.2024

References Plant Physiology 2011. 157(4):1746-64 Methods Mol Biol. 2016; 1376: 175–194 J Biol Chem. 2018 Sep 21; 293(38):14786–14797 Mozart, WA. 1786. Voi che sapete" (from: Le nozze di Figaro, K492.) https://youtu.be/tH93uhBs5m8?si=GVfvA5r_QlrVJJgq

Authentic Biochemistry Midsummer Lecture Series. Plant Biochemistry Interlude. Photochemistry I. Dr Daniel J. Guerra 26.7.24 26.07.2024

References Guerra, DJ.2024. Lecture notes Plant Cell. 2013 Jul; 25(7): 2661–2678 Peer J. 2023; 11: e15696 Gilliland and Massey. 1955. Sid King and the 5 Strings. "Sag, Drag and Fall." https://youtu.be/9KJzeOmHgc4?si=4GjA5H4stZDDl9nT

Immune Cell Biochemistry. B cells C.23 Postscript Authentic Biochemistry Podcast. Dr Daniel J. Guerra 23.7.24 23.07.2024

References Ungurianu, A., Manuela Drăgoi, C.,CrenguțaNicolae, A., Dumitrescu,I.-B., Grădinaru, D.,& Margină, D. (2024). Sirtuins and Melatonin: Linking Chronobiology to Inflammation andAging. IntechOpen. doi: 10.5772/intechopen.1003914 Christina M. Ridley et al. J. Biol. Chem. 2013;288:26052-26066 Journal of Cell Science 2005 118:4605-4612 PLoS One. 2015; 10(9): e0137193. Goffin and King. 1968...

Saturday evening biochemical metaphysics. Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 20.7.24 21.07.2024

References Guerra, DJ. 2024. Unpublished material. La Flame and baker. 1970. Its a Beautiful Day. "Hot Summer Day" https://youtu.be/PUXOSe_m_dc?si=752n4PanhqKP8nFv

Immune Cell Biochemistry II. B lymphocytes. c.22. Final Synthesis Authentic Biochemistry Podcast Dr. Daniel J. Guerra 18.7.24 19.07.2024

References J Pineal Res. 2017;62:e12391 PLoS One. 2015; 10(9): e0137193 Aging. IntechOpen. (2024). Sirtuins and Melatonin: Linking Chronobiology to Inflammation and Aging. doi: 10.5772/intechopen.1003914 Blood Cancer J. 2024 Dec; 14(1): 24 The Byrds (multiple artists). 1968. ""Sweetheart of the Rodeo". (Lp). https://youtu.be/zxzV5XoLpto?si=OFb3eHDb2ghdz16V Ravel, M. 1928. "Bole...

Immune Cell Biochemistry II. B lymphocytes. c.21. CD38 NAD+ hydrolase mediates the Inflammatory Response Authentic Biochemistry Podcast Dr. Daniel J. Guerra 16.7.24 17.07.2024

References Cells 2020, 9(1), 228 Front. Immunol. 2020. vol 11. 29 November. FEBS 2013. Volume280, Issue15 August:3530-3541 Cell Metabolism 2016. 23, 1127–1139 Beethoven. LV . 1800. Septett Es-Dur op. 20 https://youtu.be/pXsj43qCcUA?si=r5vW4PpfzvywF9b3   Jacques Revaux   Gilles Thibaut and  Claude François 1967. "My Way". Sinatra https://youtu.be/qQzdAsjWGPg?si=YWKurvGp9Xt0TYK1

The Prevailing Gignesthai of Biological Systems: “In inceptum finis est”.Dr. Daniel J. Guerra. Authentic Biochemistry Podcast. Lectures on Biochemical Epistemology.14.7.24 15.07.2024

References Guerra, DJ. 2024. Unpublished works Schubert, F. 1827. Piano Trio No. 2, op. 100 (D929) https://youtu.be/yFyv7c1XyYU?si=T0VYKT-EJ5wQmQZU Moody Blues. 1968. In Search of the Lost Chord lp. https://youtu.be/gEj3NOW_ctw?si=Uwc1evf38wMAXdJ_

Immune Cell Biochemistry II. B lymphocytes. c.20. The gignesthaic a priori events controlling pro and anti-oxidative metabolism are linked to the core circadian oscillator complex via multiple events. 14.07.2024

References Circ Res. 2018 Sep 14; 123(7):868–885. IntechOpen. 2024. doi: 10.5772/intechopen.1003914 Intl Myeloma Foundation 2024. Clin Biochem Rev. 2009 Aug; 30(3): 105–111. Br J Pharmacol. 2018. Aug; 175(16): 3251–3262 Int J Mol Sci. 2020. Nov; 21(22): 8609 Telemann, G.P. 1733. Tafelmusik https://youtu.be/VTP9evStK64?si=3m_Mw3B7IFo0i_el

Immune Cell Biochemistry II, c.19. Fine e. CNS and Immune B cell Sirtuin and melatonin regulation of inflammation and gene expression in senescence and disease. DJGPhD.11.July.24. 11.07.2024

References Circ Res. 2018 Sep 14; 123(7): 868–885 Ungurianu, A., Manuela Drăgoi, C.,Crenguța,Nicolae, A., Dumitrescu,I.-B., Grădinaru, D.,& Margină, D.2024. IntechOpen. doi: 10.5772/intechopen.1003914 Blood Cancer J. 2024 Dec; 14(1): 24

Immune Cell Biochemistry.Authentic Biochemistry Podcast Glucosyl Ceramide and NAD+. B cells lecture c.18 Fine d July 9, 2024 Dr Daniel J. Guerra 09.07.2024

References Nature Reviews Endocrinology 2020.volume 16:224–233 Blood Cancer J. 2024 Dec; 14(1): 24 Blood (2009) 114 (22): 1349. BioMedicine Hub 2021. 6:138-144. Int J Mol Sci. 2019 Mar; 20(5):1223. Lamm, R. 1969. "Does anybody really know what time it is? "[CTA lp] https://youtu.be/9FzCWLOHUes?si=kh_0eQNVliY_YieT Miller, S. 1970. "Industrial military complex blues. [Steve Miller Ban...

Immune Cell Biochemistry. Authentic Biochemistry Podcast Multiple Myeloma Sphingosine 1-P Associations. B cells lecture c.17 Fine (c) July7, 2024 Dr Daniel J. Guerra 07.07.2024

References Guerra, DJ. 2024. Lipid lectures. Blood Cancer J. 2024 Dec; 14(1): 24 Haydn. JM.1771. Requiem Mass in C Moll. https://youtu.be/0ywDPn2Ykks?si=hkL4RzjRl7WbiVER Mann, M . 1978. "Institute Chicago" Manfred Mann Earth Band. [Watch, lp] https://youtu.be/99306Peyit0?si=dQgB8m7_TmkRpXsW

Dialectical Synthesis IV. The GABA/Glutamate axis and the complexity of symmetry composed a priori. DJGPhD.03July24. Authentic Biochemistry Podcast 04.07.2024

References Guerra, DJ. 2024. Manuscripts in preparation. Paganini , N. 1819. Violin Concerto No 1. Op6. https://youtu.be/e52mkjorLAY?si=YhamClbb9LkUWOGf Hunter-Garcia. 1972. "US Blues" Grateful Dead https://youtu.be/cr-iGxbALnc?si=ImRdGq0Evh03vUd2 Miller, S. 1968. "Livin' in the USA" https://youtu.be/6Hv6WXSt7vs?si=JLdzYmlWuyRp8uIm Simon, P. 1968. "America" https:...

Immune Cell BiochemistryAuthentic Biochemistry Podcast Multiple Myeloma Dyslipidaemia B cells lecture c.16 FineB July2, 2024 Dr Daniel J. Guerra 02.07.2024

References Nature Metabolism.2019.volume 1, pages754–764 Blood Cancer J. 2024 Dec; 14(1): 24. Front Oncol.  2022; 12: 925807 Miller, S. 1970 "Going to the Country" SMB-V https://youtu.be/c6yZI0fWtSI?si=03JpEJx0LzZqKD4D

Immune Cell Biochemistry.Authentic Biochemistry Podcast Multiple Myeloma Dyslipidaemia. B cells lecture c.15 Fine(a) 30.6.24 Dr Daniel J. Guerra. Authentic Biochemistry. 01.07.2024

References Clin Exp Med. 2023; 23(7): 3373–3390. Blood Cancer J. 2024 Dec; 14(1): 24. Archivum Immunologiae et Therapiae Experimentalis. 2013 .Apr;61(2):119-25. Int. J. Mol. Sci. 2019, 20(6), 1505. Winkelmann, B. 1970."Good Morning" Steve Miller Band V. https://youtu.be/RhI-46SbsDk?si=ovfiAZREgBKUBOBw Lennon-McCartney. 1967. "Good Morning" Beatles. Sgt. Pepper's Lonely Hear...

Dialectical Synthesis Lecture III. The Necroptotic event in cell fate through the lens of categorical synthesis of the a priori. Dr Daniel J. Guerra. authentic Biochemistry Podcast 28.6.24 28.06.2024

References Guerra, DJ. 2024. unpublished writings. Seminars in Cell & Developmental Biology2020. 99:86-95

Immune Cell Biochemistry. B cells. The XIST-RNP complex with histone epigenetic alteration of Xi -linked genomic loci mediates SLE and RA in women. DJGPhD. 25.6.24. Authentic Biochemistry Podcast 25.06.2024

References J Biomed Sci 2017. 24, 63. Cell Death & Disease 2014. volume 5, page e1416 Haematologica. 2022 Mar 1; 107(3):721–732 Nucleic Acids Res. 2022 Jan 7; 50(D1): D413–D420 Oncogene 2017. volume 36, pages 5593–5608 Cell. 2021 Apr 1; 184(7):1790–1803.e17. Van Zant and Collins. 1973. "Tuesday's Gone" Lynyrd Skynyrd. https://youtu.be/LJrFxnvcWhc?si=EoL42Pw72Qe_atsz Lennon-McCart...

Dialectical Synthesis Lecture II. 23.6.24 The Apothecary of the Alternative a priori: of Programmed cell death ontology. Dr Daniel J. Guerra Authentic Biochemistry Podcast 24.06.2024

References Cell.2020 Mar 19; 180(6): 1115–1129.e13. Guerra, D.J. 2024. Intellectual materials. Goffin and King. 1962. "Up on the Roof" [Drfifters] https://youtu.be/puM1k-S86nE?si=LXzWj3SqiqHnr3JB Whitfield and Strong. 1969. "War" [Edwin Starr] https://youtu.be/dQHUAJTZqF0?si=bfB-xARpa6aVDwQg Kay and Godon 1963. "Thats Life" [Frank Sinatra] https://youtu.be/TnlPtaPxXfc...

Authentic Biochemistry: Dialectical Syntheses Toward an Improved Evaluation of Biochemical Research. Dr Daniel J. Guerra.20.6.24. 21.06.2024

References Guerra, Daniel J. 2024. Essays and Notes. Blood. 2017 Jun 15;129(24):3237-3244. Bach, JS. 1731. Partita 6 in E Minor https://youtu.be/TCrZyi0Sots?si=8bjua1HY5M_YWuin Simon, P. 1968. "Old Friends" https://youtu.be/c3NYWzHLEZw?si=vheTMVMR7f-2Ebgj

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