Anesthesia Updates

This episode discusses the main findings of a new study from Sajdeya et al., 2025 , published in Regional Anesthesia & Pain Medicine . The research asks a timely, important question: Does cannabis use affect postoperative pain in older adults? We've seen rising cannabis use among seniors, up to 5% nationally , but almost no data on how it affects acute surgical pain. This study finally giv...

This episode discusses the main findings from a 2025 review by Suleiman et al. published in BJA, examining how we should manage direct oral anticoagulants (DOACs) in patients having neuraxial anesthesia and deep peripheral nerve blocks . Traditionally, the ASRA guidelines have leaned heavily on long DOAC interruption times and selective drug level testing to avoid the rare but devastating complica...

In this episode of Updates in Anesthesiology , we discuss a 2025 Anesthesiology Clinical Focus Review on the perioperative management of patients receiving maintenance hemodialysis. This review reshapes how we assess, prepare, and manage a rapidly growing surgical population at exceptionally high perioperative risk. From hidden cardiovascular disease and fluid shifts to electrolyte traps, medicati...

In this episode of Updates in Anesthesiology , we discuss one of the most significant airway guideline updates in a decade. The Difficult Airway Society’s 2025 guidelines reshape how we approach unanticipated difficult tracheal intubation in adults. From first-attempt success and videolaryngoscopy for all, to peroxygenation, physiologically difficult airways, linear algorithms, and a renewed empha...

In this episode of Updates in Anesthesiology , Dr. Hadzic discusses a 2025 Anesthesia & Analgesia trial that challenges a long-standing airway management routine. Could high-flow nasal oxygen (HFNO) replace the laryngeal mask airway (LMA) for short general anesthesia cases without muscle paralysis ? This randomized trial puts it to the test, reporting surprising results on safety, comfort, and...

In this episode of Updates in Anesthesiology , Dr. Hadzic discusses a 2025 RAPM study comparing the classic lidocaine–bupivacaine mix to 0.5% bupivacaine alone for infraclavicular blocks. The results? Mixing speeds onset but slashes duration by nearly 14 hours. Tune in to learn why faster isn’t always better, how adjuvants like dexamethasone already optimize your block, and when it’s finally time...

In this episode of Updates in Anesthesiology , Dr. Hadzic discusses a 2025 review that reshapes how we manage bleeding in children. From restrictive transfusion thresholds and viscoelastic testing to the revival of whole blood and smarter use of TXA, pediatric hemostasis is entering a new era. Tune in to learn why kids aren’t just “small adults,” how to individualize transfusion decisions, and the...

In this episode of Updates in Anesthesiology , Dr. Hadzic discusses the main findings from a 2025 BJA review by Tinsley et al. The study reported how to manage non-insulin diabetes medicines in the perioperative period safely. From metformin’s misunderstood safety profile to the hidden risks of SGLT-2 inhibitors and GLP-1 agonists, you’ll learn which drugs to hold, which to continue, and how to pr...

A 2025 Anesthesiology meta-analysis shows that the best pain control after total hip arthroplasty comes from combining regional anesthesia with local infiltration analgesia (LIA). While LIA alone is effective, adding a quadratus lumborum or pericapsular nerve group (PENG) block significantly improves pain relief, reduces opioid use, and preserves mobility. The takeaway: stop choosing between techn...

In this episode of Updates in Anesthesiology , Dr. Hadzic unpacks a landmark 2025 study, which challenges the long-held belief that intraoperative hypotension (MAP < 65 mm Hg) contributes to postoperative delirium in older adults. With nearly 40,000 patients analyzed and no association found, it’s time to rethink reflexively chasing MAP thresholds. Tune in to hear why blood pressure might not b...

In this episode of Updates in Anesthesiology , Dr. Hadzic delves into a 2025 study, which analyzed over 53,000 surgical cases. The key finding? Neuromuscular blockers increase the risk of postoperative delirium in older adults, unless they’re properly reversed. Whether you use sugammadex or neostigmine, reversal agents significantly reduce this risk. Tune in to hear what this means for your clinic...

In this episode of Updates in Anesthesiology , Dr. Hadzic unpacks the latest evidence on pharmacologic agents for perioperative cardioprotection in noncardiac surgery. From beta-blockers and statins to the evolving debate around RAAS inhibitors and aspirin, we cover what works, what doesn’t, and what’s still unclear. Plus, we discuss whether tighter blood pressure control or postoperative therapy...

In this episode, Dr. Hadzic discusses the main findings from a new study from the British Journal of Anaesthesia (2025). The study reported that 1 in 4 children having noncardiac surgery has preoperative anemia , and that both anemia and transfusion independently, and especially together, increase 30-day mortality and complications . Despite strong global guidelines for blood management and anesth...

In this episode of UPDATES IN ANESTHESIOLOGY , Dr. Hadzic reviews a 2025 paper from Anesthesiology on managing obstetric anesthesia for patients with diabetes. From prelabor planning to postpartum glucose shifts, this episode covers everything you need to provide safe and effective anesthesia care for this growing population of high-risk parturients. Where else to find us: Web- ⁠⁠http://www.nysora...

 In this episode of the  NYSORA Podcast: Updates in Anesthesiology , Dr. Hadzic breaks down what anesthesiologists need to know about using AI in clinical practice. We cover recent studies showing where AI like ChatGPT performs well (like data analysis) — and where it can be risky, especially in complex patient cases. You’ll also learn how NYSORA’s  Anesthesia Assistant App , powered by Maia, give...

In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic unpacks Hepatopulmonary Syndrome (HPS), a frequently missed but life-threatening complication of chronic liver disease. Drawing on a 2025 review from Current Opinion in Anesthesiology, we cover the mechanisms of HPS, key diagnostic clues like platypnea and orthodeoxia, and why liver transplantation remains the only curative therapy. You’ll a...

In this episode of NYSORA’s Updates in Anesthesiology , Dr. Hadzic breaks down the 2024 ESAIC guidelines on postoperative delirium (POD) in adults. Discover the latest evidence on risk factors, why inflammation, not just anesthesia, may be the real culprit, and why multicomponent nonpharmacological strategies are your best bet. Learn what works, what doesn’t, and how to protect your patients from...

In this episode, Dr. Hadzic unpacks a 2025 British Journal of Anaesthesia systematic review led by Dr. Grant and colleagues, exploring the hidden dangers of common analgesics, opioids, NSAIDs, and gabapentinoids in patients with multiple chronic conditions. With over 2.6 million patients studied, the findings reveal clear red flags and critical evidence gaps. Tune in for practical insights, risk-r...

In this episode of Updates in Anesthesiology , Dr. Hadzic unpacks the latest evidence on sugammadex-induced anaphylaxis from the 2025 Anesthesiology review by Dr. Savic and colleagues. We explore the benefits that make sugammadex the preferred reversal agent over neostigmine, and the rare but serious risk of hypersensitivity reactions. You'll learn about proposed mechanisms, diagnostic pitfall...

In this episode of Updates in Anesthesiology , Dr. Hadzic reviews a double-blind RCT from Anesthesia & Analgesia (March 2025) led by Dr. Ajetunmobi and colleagues. The study compared sugammadex and neostigmine for neuromuscular blockade reversal in morbidly obese patients with OSA undergoing bariatric surgery. Despite sugammadex’s pharmacologic advantages, the study found no significant differ...

In this episode of Updates in Anesthesiology , Dr. Hadzic discusses  a 2025 study by Corpman et al. evaluating ChatGPT-4, Bard, and other AI chatbots as decision support tools in regional anesthesia. The findings? AI is getting smarter, but it still makes major clinical errors. Enter MAIA, NYSORA’s purpose-built AI assistant, designed by anesthesiologists to bridge the gap between innovation and s...

 In this episode of UPDATES IN ANESTHESIOLOGY , Dr. Hadzic breaks down a landmark study by Garcia-Casanovas et al., published in Anesthesiology (July 2025), involving over 30,000 joint arthroplasty patients across 43 hospitals. The study shows that higher adherence to patient blood management (PBM) guidelines isn't just about fewer transfusions; it leads to fewer complications, shorter hospita...

In this episode of  Updates in Anesthesiology , Dr. Hadzic reviews the newly published 2025 international clinical practice guidelines on  platelet transfusion , co-led by Dr. Ryan Metcalf from the University of Utah and Dr. Simon Stanworth from Oxford, and published in  JAMA . Based on evidence from over 30 studies, these guidelines recommend  restrictive platelet   transfusion thresholds  in bot...

In this episode of Updates in Anesthesiology , Dr. Hadzic breaks down the results from the PRECISION study published in Anesthesiology (2025). Led by Dr. Cui and colleagues, this prospective trial reveals that nearly 1 in 9 older patients undergoing noncardiac surgery, especially neurosurgical, experience covert strokes detectable only by MRI. These “silent” strokes double the risk of postoperativ...

In this episode of Updates in Anesthesiology , Dr. Hadzic breaks down the largest real-world study to date comparing the environmental impact of general anesthesia strategies. With over 35,000 cases analyzed, discover why TIVA with propofol has emerged as the lowest carbon emitter, outperforming even optimized sevoflurane techniques. We’ll explore the GHG numbers, plastic waste concerns, and clini...