ACR Journals On Air

Our guest this week is Dr. April Barnado,   the first author of a study which analyzed a cohort of 3.2 million pat ients with Systemic Lupus Erythematosus (SLE), during pregnancy, from 1989 to 2020. Her team's work, titled  " Systemic Lupus Erythematosus Delivery Outcomes Are Unchanged Across Three Decades " was published in "ACR Open Rheumatology ", and found some amazing trends regarding outcome...

O ur guest this week is Dr. Tony Merriman, whose latest work : " Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout " , attempted  to determine whether a gout polygenic risk score (PRS) is associated with age at gout onset and tophaceous disease in European, East Polynesian, and West Polynesian men and women with gout....

This week we get to "The Heart of the Matter" a little differently. To begin, our guest is the first author of a manuscript whose objective was to determine the prevalence and correlation of subclinical myocardial inflammation in patients with rheumatoid arthritis (RA), titled: " Myocardial Inflammation, Measured using 18-FDG-PET-CT is associated with Disease Activity in Rheumatoid Arthritis " . H...

Our guest this week, Dr. Alexandru-Emil Matei, is the first author of a study that endeavored to evaluate immune cell activation in scleroderma. His study, written for the completion of his medical training in Romania is titled: " Identification of a Distinct Monocyte-Driven Signature in Systemic Sclerosis Using Biophysical Phenotyping of Circulating Immune Cells" ( recently published in " Arthrit...

C aring for older adults who suffer from rheumatic disease comes with it the need to manage multimorbidity, p olypharmacy, and geriatric syndromes . Often, shifting priorities for those suffering with rheumatic musculoskeletal diseases (RMDs) is needed, sometimes leading to a prescribing cascade. The practice of 'deprescribing ', an ap proach to optimize medication use to deliver a more 'goal-conc...

In a study recently published in "ACR Open Rheumatology" titled: " Geographic Variation in Disease Burden and Mismatch in Care of Patients With Rheumatoid Arthritis in the United States ", first author Dr. Sharon Dowell set out to understand some of the factors associated with regional variation of rheumatoid arthritis in the United States. Sharon Dowell, MD presents her study's findings and concl...

Pulmonary hypertension (PH) , being a serious complication of systemic sclerosis ( SSc ) , develops late in the course of SSc and carries with it a poor prognosis. With the median survival of about 3 years, new evid ence suggests that early diagnosis and treatment can significantly improve survival . Joining us this week is Christopher P Denton PhD FRCP, senior author of " Dynamic Prediction of Pu...

Dr. Joshua Baker, f irst author of a paper recently published in "Arthritis & Rheumatology", " Associations Between Low Serum Urate, Body Composition, and Mortality " , is our guest today. Dr. Baker, recognizing the controversy in whether low serum urate or uric acid (UA) level contribute to ad verse outcomes , set out to evaluate the relation between low serum UA levels and sarcopenia , to assess...

When rheumatology concepts battle it out in a team bracket tournament, you get "Rheum Madness"! " A place for everyone who is crazy about rheumatology to connect, collaborate and compete " in a n on line , learning experience , created by Dr. David Leverenz . His body of work , " Rheum Madness: Creating an Online Community of Inquiry " , featured in this episode, analyzes participant engagement an...

Osteoarthritis is incredibly common, affecting more than 500 million people across the globe. It is a significant cause of pain and disability and carries high healthcare costs and societal burdens. Around the world, there are not enough rheumatology specialists to treat all the patients with OA, and in many countries, OA management is coordinated by primary care internists. However, despite good...

In this week's episode, we'll be looking at a paper recently published in " ACR Open Rheumatology" titled: " Machine Learning Applied to Patient-Reported Outcomes to Classify Physician-Derived Measures of Rheumatoid Arthritis Disease Activity " . This study used machine learning tools to investigate whether longitudinal patient-reported outcome data can be a proxy for Clinical Disease Activity Ind...

This week, we welcome Dr. Ruth Fernandez Ruiz to our show , a physician-scientist and Assistant Professor of Medicine at Weill Cornell Medical College and Hospital for Special Surgery in New York City . Dr. Fernandez Ruiz 's award-winning work focuses on the interplay of genetic variation, type I interferons, and immune dysregulation in lupus. However, her latest study published in "Arth ritis & R...

Dr. Patricia Katz is our guest this week as she presents her latest study " Sleep Disorders among Individuals with Rheumatoid Arthritis " , recently published in "Arthritis Care & Research". This study focuses on patients with RA who self-report common sleep problems such as obstructive sleep apnea, restless leg syndrome and short sleep and examines the prevalence of these disorders plus their pot...

In this episode, Dr. Shanmugam discusses " A Randomized, Placebo-controlled Phase 3 Extension Trial of Long-term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus ", a three-year   long-term study designed to understand the safety of an i frolumab in patients with systemic lupus erythematosus (SLE) . This study, which was recently published in "Arthritis & Rheumatology"...

In this episode, we welcome the lead author of " Deucravacitinib, a Tyrosine Kinase 2 Inhibitor, in Systemic Lupus Erythematosus: A phase 2, Randomized, Double-Blind, Placebo-Controlled Trial " Dr. Eric Morand of Monash University. The objective of this multicenter clinical trial in lupus (recently published in " Arthritis & Rheumatology ") was to assess the efficacy of deucravacitinib in a phase...

Join us this week as we interview the lead author of " Genicular Nerve Block for Pain Management in Patients with K nee O steoarthritis: A R andomized P lacebo- C ontrolled T rial " , Dr. Michael Shanahan. Dr. Shanahan's study, most recently published in "Arthritis & Rheumatology" attempts to determine the efficacy of ultrasound-guided genicular nerve block in managing pain in patients with knee o...

This week, our guest is Dr. Grace Lo, first author of " Association Between Walking for Exercise and Symptomatic and Structural Progression in Individuals with Knee Osteoarthritis: Data from the Osteoarthritis Initiative Cohort " And Assistant Professor at Baylor College of Medicine. The objective of her study: To asses s the relationship between walking for exercise and symptomatic and structural...

This week on 'Journals', Dr. Shanmugam has invited Dr Joann B Sweasy and Dr. Westley Reeves to discuss a paper with an interesting journey, " A Human MSH6 Germline Variant Associated with Systemic Lupus Erythematosus Induces Lupus-Like Disease in Mice ". In this paper, we discover that the science is always telling us something, regardless of where we believe we're headed and where we ultimately e...

In this week's episode, Dr. Shanmugam welcomes Dr. Mary Beth Son, the senior author and corresponding author of  " Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies ." This  study  sought to determine whether the application of dif fere nt MIS-C definitions and differing disease severity in  patients   participatin...

This week we welcome Dr. Jamie Collins , lead author of " Five-Year Structural Changes in the Knee Among Patients With Meniscal Tear and Osteoarthritis: Data From a Randomized Controlled Trial of Arthroscopic Partial Meniscectomy Versus Physical Therapy " . We discuss this study's methods, statistical results and what all that data indicates about the role of exercise and surgery. Later, Dr. Colli...

In this episode, we welcome Dr. Dua and Dr. Bolster to the show, co-first authors of " Virtually Speaking: The impact of a Nationwide Synchronous and Asynchronous Learning Forum. " and  discuss the study 's findings a long with their educational collaborative initiative Virtual Fellows in Training (VFIT) , which includes a compendium of online courses: Virtual Rheumatology Learning Collaborative (...

In our inaugural episode we welcome Dr Monica Yang, lead author for " Reactogenicity of the Messenger RNA SARS–CoV-2 Vaccines Associated With Immunogenicity in Patients With Autoimmune and Inflammatory Disease " and Dr. Maria Danila the Associate Editor for the manuscript. We discuss some of the findings their COVID19 Vaccine Response in Patients with Autoimmune Disease (COVARiPAD) study found, de...

The American College of Rheumatology's newest podcast series featuring interviews, commentary, and analysis on research from our three peer-reviewed journals. Whether it's an expert analysis of a manuscript or deep dive with an author – our goal is the same – to understand the impact of the science and bring it from the bench to the bedside.