Raise the Line

A singing guest!  A poetic chat bot! This special episode of Raise the Line features those unusual artistic highpoints along with the substantive and interesting conversation you always get with host Shiv Gaglani. Our guest, Dr. Mark Korson, is a metabolic geneticist and Director of Education and Physician Support Services at VMP Genetics who believes patients have a crucial role to play in the ed...

“There's a real diversity of jobs available that folks don’t always think about initially when they think about going into healthcare,” says Marc Cummings, the President and CEO of Life Science Washington, a nonprofit trade association serving the life sciences industry in the state of Washington. Dr. Tina Albertson, the Chief Medical Officer at nearby Lyell Immunopharma, agrees. For instance at h...

“With psychedelics right now, there's a lot of hype around the compound, which is somewhat important, but Sunstone Therapies is really founded on the belief that the delivery is more important than the drug,” says Dr. Manish Agrawal, the company’s co-founder and CEO. As interest in the use of psychedelics for mental health treatment grows and various compounds continue to move down the path of FDA...

Our guest on this episode of Raise the Line, Dr. Githinji Gitahi, ended up in the medical field because he’s always had a nagging need for social justice. “That was a place that I found where social justice is needed and is probably the foundation for healthy populations,” he tells host Shiv Gaglani. Dr. Gitahi is the Group CEO of Amref Health Africa, the leading Africa-based health development in...

Why is it that Hispanics make up 20% of the U.S. population, but only 6% of the physician workforce? Well, Dr. Pilar Ortega, founding president of the National Association of Medical Spanish and co-founder of the Medical Organization for Latino Advancement, is working towards closing that gap. As an immigrant herself, she and her family have experienced trying to navigate a medical system that was...

“Patients don’t understand how little we actually know in medicine. I'm not sure if doctors understand this, either,” says Dr. Lisa Sanders, an associate professor at Yale School of Medicine who is perhaps best known as the author of the “Diagnosis” column for the New York Times Magazine . You’re in for more of that refreshing frankness from Sanders whose fascinating career path includes network T...

“In medical school, you don't learn about leadership. You don't learn about what skills are required to make large-scale strategic decisions that can impact your patients,” says Nita Gombakomba, who will complete her medical degree later this year at the University of Maryland School of Medicine.  As national president of the Student National Medical Association -- which has been fighting for equi...

“I know it's hard for people to think about holding on if they're in despair, but there's the possibility of healing coming ahead. Don’t give up hope,” says Dr. Rick Doblin, who has devoted his career to getting MDMA and other psychedelics approved by the FDA.  As you’ll hear in this episode of Raise the Line , he could be on the verge of seeing his decades-long dream come true.  On the day host S...

The growth in skepticism about science that was fueled by disinformation during the pandemic has been a frequent topic on Raise the Line, with many insightful guests from medicine and academia offering analysis of the problem and possible solutions. On today’s episode, we’ll hear from someone who is very well-placed to actually make progress on this front. Max Bronstein, the Assistant Director for...

“It's still early days in the application of all this technology relative to its long-term potential, but even so, it's already producing some big wins for patients,” says Dr. Matthew Might, whose impactful career in computer science and medicine has been shaped by the rare disease odyssey of one of his children. His son, Bertrand, was the first person in the world diagnosed with a particular form...

We welcome one of the nation's most respected health and health policy thought leaders to Raise the Line  on this episode .  Susan Dentzer’s remarkable career includes many years of reporting on healthcare for major national news outlets, being a senior policy adviser to the Robert Wood Johnson Foundation and serving as a board leader in medical education and health system delivery, just to name a...

“There's a reservoir of hope, energy and optimism many of us have that we may not know about until we're really tested,” says attorney and author Scott Reich. The heavy test he and his wife Ilissa have endured for the past three years started when their infant son Eli was diagnosed with a rare brain disorder called FOXG1 Syndrome which causes severe seizures and impedes normal movement, speech and...

“I’m currently sitting 100 feet away from a giant lab full of robots where we can do up to 2.2 million experiments a week,” says Dr. Chris Gibson, the Co-Founder and CEO of Recursion, a company whose mission is to create a more efficient path to drug discovery. You are going to hear a lot of mind-boggling numbers from Chris in today’s Raise the Line episode, but they all boil down to this: advance...

You might think improving healthcare quality is largely in the hands of the clinicians providing the care, but much of this challenging work is actually done behind the scenes by professionals who lead quality reviews, institute new protocols for safer care and focus on performance improvement, among many other efforts. “We are on a journey to really change the perception of what quality is. We wa...

Regular listeners to Raise the Line know so-called "rare diseases" aren't really rare when you consider up to thirty million Americans are affected by them directly. That makes it likely you know someone who is impacted, or you know one of their colleagues, friends or loved ones. That fact has hit home at Osmosis over the last few months as we've started planning a major focus on rare diseases for...

Grace Wilsey was born with a deadly genetic mutation so rare that at the time of her birth, it had never been identified in another person. The disorder, NGLY1 deficiency, causes a wide range of physical and cognitive problems such as muscle weakness, speech deficiencies and seizures. “The NGLY1 gene is in every cell in the body. It's almost like a firefighter that's on call, ready to go when ther...

“You know, it's easy to say that default answer that everything's okay, but it's really not. She's lost a lot of her vision, she's got hundreds of seizures at night, and she's having difficulty walking,” shares Luke Rosen about his eight-year-old daughter Susannah.  She was born with KIF1A-associated neurological disorder -- or KAND -- a rare, degenerative genetic disease for which there is curren...

As we continue our focus on rare diseases on Raise the Line , we’re delighted to be joined by Dr. Alaa Hamed, Global Head of Medical Affairs, Rare Diseases at Sanofi, one of the leading pharmaceutical companies in the world. Although most well known for their focus on lysosomal storage disorders including Gaucher and Pompe disease, Dr. Hamed and his team at Sanofi are also working in adjacent dise...

“Imaging has really become the tip of the spear of the patient journey,” says Daniel Arnold, CEO of Medality. In order to train future radiologists in this critically important and complex specialty, and keep current practitioners on top of their game, Arnold and his team are on a mission to transform the way radiologists learn by offering an online solution that mimics practicing radiology in the...

“One of the reasons I really wanted to be at Walmart is that you're touching people that truly have a need,” says Dr. John Wigneswaran, the retail giant’s Chief Medical Officer.  And giant is not an overstatement.  150 million Americans visit a Walmart every week, and there is a store within ten miles of 90% of the U.S. population.  In terms of healthcare, there are roughly 5,000 Walmart pharmacie...

It’s not hard to start feeling relaxed when you experience a virtual reality visit to a mountain top, taking in the beautiful views of forested peaks and valleys and hearing the rustling breeze. You can actually feel transported from the real world.  But imagine how much more transporting it would be if you could also smell the pine trees? Well, now you can, thanks to OVR Technology, a Vermont-bas...

“We're the richest country on the planet, healthcare access has to be core to who we are,” says Karthik Ganesh, CEO of EmpiRx Health, one of the fastest growing healthcare services companies in the country and the industry’s only value-based Pharmacy Benefit Manager.  Ganesh and his team believe that radical changes are needed in the country’s healthcare system and they’re working to create a bett...

Would you rather be poked with a needle, or get a diagnosis from a non-invasive scan? Most of us would choose the latter, if we had the option.  Needle biopsies also come with the risk of infection and other complications that can be avoided by obtaining a diagnosis via imaging. Those are just some of the advantages underpinning the work of Perspectum, a global precision health company focused on...

“We know that whenever nurses are listened to in policymaking arenas, health outcomes improve,” says Dr. Michelle Acorn, chief nurse at the International Council of Nurses, a federation of nursing associations. That’s why she’s focused on making sure nurses are at the decision-making tables all over the world. “ICN ensures that nurses have a voice in developing and implementing health policy so th...

Science As a Force for Social Good: Dr. Richard Horton, Editor in Chief of The Lancet   The first scientific paper on the clinical features of patients infected with what came to be known as COVID-19 was published in The Lancet, launching that famed journal's prominent role in COVID research, which it has maintained throughout the pandemic. But being an influential force in science and medicine is...