Pearls and Prep

The principal focus of this podcast episode revolves around the exceedingly high suicide risk observed during the initial week following psychiatric hospital discharge. In this discussion, we delve into an illuminating multiple-choice question that challenges our understanding of psychiatric vulnerabilities. The episode underscores the alarming statistic that, within the first three months post-di...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving into the heavyweight showdown between Seroquel and Lamictal to see which medication packs a better punch for bipolar depression. Spoiler alert: Se...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We've got a juicy nugget for you today: one in seven patients starting on antidepressants might develop bruxism, which is basically the fancy term for grinding your t...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving deep into the tricky world of pharmacotherapy—specifically, figuring out the least appropriate meds for our buddy(mock patinet) Lenny, who’s juggl...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the wild world of pharmacokinetics with a case that's got more twists than a soap opera. Our star (MOCK) patient, Desiree, is dealing with bi...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We're diving into a super relevant topic today about long-acting injectables, specifically Invega Sustenna, and trust me, it's packed with pearls to keep you sharp! W...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We’re diving into a wild case today with our girl Bonnie, who's all sunshine and rainbows—except for those pesky positive drug screen results that have us scratching...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode elucidates the intricacies surrounding the case of a mock patient named Larry, who presents with persistent morning fatigue despite an improvement in his depressive symptoms. The primary focus of our discuss...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Alright, folks, let’s dive into a real eye-opener about metformin and its under-prescription among patients on second-generation antipsychotics. Believe it or not, only about 2 to 3% of these patients are actually getting the he...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving deep into the wild world of mood disorders, specifically focusing on the juicy details around bipolar disorder and its sneaky symptoms. You know, the kind of stuff that can trip you up if you’re not paying at...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This episode delves into the complexities of managing acute bipolar depression, emphasizing the imperative to address the patient's immediate depressive symptoms. We engage in a comprehensive discussion that elucidates the vario...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the wild world of psychiatric medications and their sneaky side effects. Spoiler alert: Ambien is the real troublemaker, causing a whopping 12% of emergency room visits related to psychiatric drugs. We'l...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the wild world of obstructive sleep apnea and its sneaky link to depression. Turns out, if you're dealing with sleep apnea, your chances of developing a depressive disorder can double—yeah, you heard tha...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode articulates the intricate relationship between drug affinity, occupancy, and intrinsic activity, employing a nightclub analogy to elucidate these pharmacological concepts. The primary focus is the significan...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode elucidates the concept of intrinsic activity in pharmacology, a critical aspect that pertains to a medication's ability to activate receptors upon binding, thereby producing a cellular response. Understandin...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode delves into the complex case of a 68-year-old woman presenting with atrial fibrillation and new onset depression, following the recent loss of her husband. We examine the intricacies of her treatment options...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The focal point of today's discourse centers on the medication Remeron, also known as Mirtazapine, which plays a pivotal role in addressing sleep disturbances prevalent among patients experiencing depression and anxiety. I will...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This episode delves into the complexities surrounding the medication Trazodone, particularly in the context of treating a mock patient named Randall, who grapples with generalized anxiety and sleep disturbances. We meticulously...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This episode emphasizes the importance of accurately diagnosing mental health conditions, specifically highlighting a case study where a clinician erroneously diagnosed a patient with generalized anxiety disorder (GAD) instead o...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Receptor occupancy is the focal point of our discussion today, as it is an essential concept that significantly enhances our understanding and practice in pharmacology. This concept elucidates the percentage of receptors occupie...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep CAN YOU SPOT THE 4 ERRORS IN THIS MOCK PSYCHIATRIC CASE STUDY?? **SPOILERS BELOW**** This podcast episode elucidates a critical case study involving a patient with schizophrenia, focusing on the identification of four significan...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Board Bombs - Back by popular demand! This episode delves into the intricacies of psychopharmacology, specifically focusing on the management of antipsychotic medications and mood stabilizers. We engage in a thorough examination...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The focal point of this podcast episode centers on the critical importance of continuing antidepressant treatment beyond the point of symptom remission. We elucidate the complexities surrounding this subject by exploring three e...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The current discourse delves into the pivotal concept of affinity within the realm of pharmacology, elucidating its significance for practitioners tasked with prescribing medications. Affinity is fundamentally defined as the str...

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The focal point of our discussion today revolves around the complexities of managing a patient, whom we shall refer to as Betty (mock patient) who presents with excessive daytime sleepiness and residual depressive symptoms amids...