Evidence Based Hair

A mix of recently published studies in hair loss   IRON PILL GASTRITIS   Koch R et al (starts at5 5:19). Case report: Rapid onset, ischemic-type gastritis after initiating oral iron supplementation. Front Med (Lausanne) 2022 Nov 3;9:1010897.   Laine LA et al. (starts at 9:17). Effect of oral iron therapy on the upper gastrointestinal tract. A prospective evaluation. Dig Dis Sci. (1988) 33:172–7. d...

LEARNING OBJECTIVES By the end of the podcast, the listener should be able to Discuss the benefits of HCQ in LPP Outline allergens that may be relevant in LPP/FFA Discuss the benefits of LDOM in LPP Describe the Renbok phenomenon and how it relates to FFA Outline the potential triggers for EPDS Describe the relationship between AKN and gout     EFFICACY OF HYDROXYCHLOROQUINE IN LICHEN PLANOPILARIS...

Season 3, Episode 5

Studies in Androgenetic Alopecia and Alopecia Areata   STUDIES REFERENCED   MINOXIDIL CONCENTRATIONS   Singh et al (starts at 10:10). Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit? Clin Exp Dermatol. 2022 Nov;47(11):1951-1955   Olsen EA, Dunlap FE, Funicella T et al (starts at 13:22). A randomized clinical trial of 5% topical minoxidil versus 2% topica...

Recording of the Evidence Based Hair Podcast for the Oct 24, 2022 issue.    STUDIES REFERENCED Han JJ et al (starts at 5:28) Association of resilience and perceived stress in patients with alopecia areata: A cross-sectional study. J Am Acad Dermatol. 2022 Jul;87(1):151-153.   Gressler J et al (starts at 20:55 ). Re-pigmentation of scalp hair - A feature of early melanoma. Am J Med. 2022 Sep 25;S00...

Recording of the Evidence Based Hair Podcast for the Oct 17, 2022 issue.    LICHEN PLANOPILARIS COMORBIDITY STUDIES Conic et al (starts 8:19). Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders. J Eur Acad Dermatol Venereol 2021 Nov;35(11):e826-e828. Joshi et al (starts 9:59). Comorbidities associated with lichen planopilaris: a case-control study using t...

Recording of the Evidence Based Hair Podcast for the Oct 11, 2022 issue.  TINEA CAPITIS STUDIES Cukierman E et al (starts at 5:18). Alopecia and pet: a case report. Einstein (Sao Paulo). 2022 Jul 4;20:eRC6881.   TELOGEN EFFLUVIUM - COVID 19 Visconti A et al (starts at 20:00) Cutaneous Manifestations of SARS-CoV-2 infection during the Delta and Omicron waves in 348,691 UK users of the UK ZOE COVID...

ORAL MINOXIDIL IN PEDIATRICS   Jerjen R et al (starts at 12:33). Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome. Br J Dermatol. 2021;184(5):977-978. Nicolas-Ruanes et al (starts at 15:33). Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric population: A descriptive study. J Am Acad Dermato...

FRONTAL FIBROSING ALOPECIA : ISOTRETINOIN VS FINASTERIDE Rakowska A, et al (starts at 9:15). Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases. J Drugs Dermatol. 2017. Rokni GR et al (starts at 10:43). Evaluating the combined efficacy of oral isotretinoin and topical tacrolimus versus oral finasteride and topical tacrolimus in fro...

STUDIES REFERENCED   COVID RELATED SHEDDING   Mazeto IFS et al (starts at 6:09). Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20.   Czech T et al (starts at 14:30). Characteristics of Hair Loss after COVID-19: Systematic Scoping Review. J Cosmet Dermatol. 2022 Jul 8.     TRICTHOTILLOMANIA   Tho...

Kavadya T and Mysore V (starts at 5:24). Role of Smoking in Androgenetic Alopecia: A Systematic Review. Int J Trichology. 2022 Mar-Apr; 14(2): 41–48.   Mosley JG and Gibbs AC (starts at 6;30). Premature grey hair and hair loss among smokers: a new opportunity for heatlh education? British Medical Journal 1996; 313: 1616.   Su LH and Chen T H-H (starts at 7:38) Association of Androgenetic Alopecia...

JAK KINASE INHIBITORS AND SKIN CANCER Jalles et al (starts at 5:29). Skin cancers under Janus kinase inhibitors: A World Health Organization drug safety database analysis. Therapie. 2022 May 7;S0040-5957(22)00092-0.   ISOTRETINOIN LAB MONITORING Xia E et al (starts at 13:36). Isotretinoin Laboratory Monitoring in Acne Treatment: A Delphi Consensus Study. JAMA Dermatol. 2022 Jun 15.   ISOTRETINOIN...

The third Monday of the month is dedicated to studies in scarring alopecia.   LICHEN PLANOPILARIS   Kahjoogh et al (starts at 5:34). Efficacy, safety, tolerability and satisfaction of N-acetylcysteine and pentoxifylline in lichen planopilaris patients under treatment with topical clobetasol: a triple arm blinded randomized controlled trial. Dermatol Ther. 2022 Jun 15   HYDROXYCHLOROQUINE Beatriz S...

DYSTROPHIC ANAGEN EFFLUVIUM IN COVID 19 SHEDDING Shanshal M (start 7:52). COVID-19 related anagen effluvium. J Dermatolog Treat. 2022 Mar;33(2):1114-1115. Anna Carolina Miola et al (starts 9:45). Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization. J Am Acad Dermatol. 2022   ALTERNATE DAY IRON DOSING Lale Aydın Kaynar et al (starts 12:57). Comparison of daily oral...

ANDROGENETIC ALOPECIA STUDIES Sanabria et al (starts at 4:40). Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18; Klein E et al (starts at 13:40). Comparing combination low-dose oral minoxidil and topical minoxidil with oral minoxidil alone for the treatmen...

Recording of the Evidence Based Hair Podcast for the May 23, 2022 issue.  ORAL MINOXIDIL USE IN PEDIATRIC PATIENTS   Nicolas-Ruanes et al (starts at 4:00). Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric population: A descriptive study. J Am Acad Dermatol. 2022 Apr 26;   Jerjen R et al. Low-dose oral minoxidil improves global hair density and len...

Evidence Based Hair Podcast for the May 16, 2022 issue.  STUDIES REFERENCED   FRONTAL FIBROSING ALOPECIA STUDIES   Arasu et al (starts at 3:40). Vitamin D status in patients with frontal fibrosing alopecia: A retrospective study. JAAD Int. 2022 Apr 18;7:129-130.   Sun et al (starts at 11:30). Extensive facial scarring after ablative laser resurfacing in a patient with frontal fibrosing alopecia. J...

Recording of the Evidence Based Hair Podcast for the April 25, 2022 issue.   STUDIES REFERENCED   ALLERGIC CONTACT DERMATITIS STUDIES Feryel A et al (starts at 3:51). Unusual clinical presentation of allergic contact dermatitis to topical minoxidil. Contact Dermatitis. 2022 Mar 28 Pham et al (starts at 12:18). Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Syste...

STUDIES REFERENCED FRONTAL FIBROSING ALOPECIA & REPIGMENTATION: Barreto TM et al (starts at 3:18). Atypical frontal fibrosing alopecia presentation in a male patient associated with spontaneous reversal of canities. J Eur Acad Dermatol Venereol. 2022 Mar 12 Defo D et al Repigmentation pilaire enbordure d’une alopecie frontale fibrosante. [Hair darkening close to a patch of frontal fibrosing alopec...

REFERENCES CITED IN THIS EPISODE (and TIME STAMP)   TELOGEN EFFLUVIUM   Monari et al (starts at 4:20). Post-SARS-CoV-2 Acute Telogen Effluvium: An Expected Complication. J Clin Med. 2022 Feb 24;11(5):1234. Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26. Guarnieri G et al (starts at 9:07). Relationship between hair s...

STUDIES HIGHLIGHTED ALOPECIA AREATA King B et al (starts at 3:27). Two Phase 3 Trials of Baricitinib for Alopecia Areata. N Engl J Med. 2022 Mar 26. Fenentinos P et al (starts at 16:24). Assessing the role of stressful life events in the induction and recurrence of alopecia areata: a case-control study. J Am Acad Dermatol.  2022 Mar 24;S0190-9622(22)00526-6. Macbeth A et al (starts at 21:14). The...

Recording of the Evidence Based Hair Podcast for the March 28, 2022 issue.       STUDIES HIGHLIGHTED   Trueb RM et al (starts at 3:27). Minoxidil-induced hypertrichosis in a breastfed infant. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):e224-e225.   Gangal et al (starts at 7:08). Mask-associated acquired trichorrhexis nodosa of the beard. JAAD Case Rep. 2022 Mar;21:101-102.   Trueb RM et al. Prepu...

STUDIES HIGHLIGHTED FFA STUDIES Dubin C et al (starts at 2:50). Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016 Starace et al (starts at 12:31). Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From...

STUDIES HIGHLIGHTED IN THIS EPISODE   TELOGEN EFFLUVIUM   Lytvyn et al (starts at 2:15). Comparing the frequency of isotretinoin-induced hair loss at

STUDIES HIGHLIGHTED IN THIS EPISODE Qui Y et al (starts at 2:41). Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645   Gupta AK et al (starts at 8:38). Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis....