Niraj Sharma MD FACC FHRS

EP Edge Journal Watch

Science EN ↓ Odcinki: 50

Welcome to EP Edge Journal Watch — where cardiac electrophysiology meets evidence, precision, and perspective. Hosted by Dr. Niraj Sharma, this bi-weekly podcast distills high-impact cardiovascular and EP research into clear, clinically meaningful insights. Each episode goes beyond headlines and abstracts to uncover what new studies actually mean for patient care, decision-making, and the future of electrophysiology. What EP Edge Journal Watch stands for:Evidence-based practicePrecision electrophysiologyA forward-thinking, edge-driven approach to how we interpret and apply data in real-world c...

Autor

Niraj Sharma MD FACC FHRS

Kategoria

Science

Ostatni odcinek

19 paź 2026

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Odcinki

EP Edge™ Journal Watch Issue 20: AF Screening, Pulsed Field Ablation, ICD Shocks, CRT in AF, and Anticoagulation After Ablation 27.04.2026

In this episode of EP Edge™ Journal Watch Issue 20 , Dr. Sharma reviews some of the most clinically relevant new developments in cardiac electrophysiology, with a sharp focus on atrial fibrillation screening, pulsed field ablation expansion, device therapy trade-offs, and post-ablation anticoagulation strategy . This issue examines how Apple Watch–based atrial fibrillation detection performed in a...

EP Edge™ Journal Watch Issue 19: Atrial Fibrillation Ablation, Conduction System Pacing, GLP-1 Therapy and Arrhythmia Risk 20.04.2026

In EP Edge™ Journal Watch Issue 19 , Dr. Sharma reviews the most important new studies in atrial fibrillation ablation, conduction system pacing, device therapy, and real-world arrhythmia risk . This episode covers a large multicenter analysis linking cannabis use with higher rates of atrial fibrillation, tachycardia, premature beats, and ventricular arrhythmias ; the LEAF study on liraglutide and...

EP Edge™ Journal Watch Special Edition: EHRA PFA Statement 2026 | What the New Guidance Means for AF Ablation 14.04.2026

In this special edition of EP Edge™ Journal Watch , Dr. Sharma takes a focused, critical look at the 2026 EHRA/ESC scientific statement on pulsed field ablation for atrial fibrillation . This episode goes beyond a surface summary to examine what the new EHRA PFA statement adds to the field, where it is most useful in day-to-day electrophysiology practice, and where important evidence gaps still re...

EP Edge™ Journal Watch Issue 18 (April 2026): AF Cancer Signals, PFA Recalibration, EMBOL-AF, SMART-ALERT, LBBAP, and VT Rescue 13.04.2026

In EP Edge™ Journal Watch Issue 19 (April 2026) , Dr. Niraj Sharma takes a high-level look at the latest developments in cardiac electrophysiology , with a sharp focus on atrial fibrillation , pulsed field ablation , embolic risk , physiologic pacing , and ventricular arrhythmia rescue strategies . This episode moves beyond routine rhythm-control discussions and examines whether new-onset atrial f...

EP Edge Journal Watch Issue 17 April 2026: CLOSURE-AF, Left Atrial Appendage Closure vs Medical Therapy, CRT Pacing Trials, PFA Cerebral Emboli, and ViV-TAVR Pacemaker Risk 06.04.2026

In this episode of EP Edge Journal Watch, Dr. Niraj Sharma reviews five clinically important studies spanning atrial fibrillation, structural heart intervention, heart failure pacing, and contemporary ablation safety. The episode opens with CLOSURE-AF, the randomized trial comparing left atrial appendage closure (LAAC) with physician-directed best medical therapy in older, high-risk patients with...

EP Edge™ Journal Watch Breaking News Special Edition: CHAMPION-AF, PRAGUE-17, and CLOSURE-AF — LAAC vs DOACs in Atrial Fibrillation 30.03.2026

In this EP Edge™ Journal Watch Breaking News Special Edition , Dr. Niraj Sharma delivers an in-depth analysis of the CHAMPION-AF trial and places its findings in direct comparative context with PRAGUE-17 and CLOSURE-AF , three pivotal randomized studies shaping the modern debate around left atrial appendage closure (LAAC/LAAO) versus direct oral anticoagulants (DOACs) for stroke prevention in atri...

EP Edge Journal Watch Issue 16: 11 New EP Trials on AF Ablation, SVT, Anticoagulation, PFA Safety, VT Pacing, and OHCA 23.03.2026

In this episode of EP Edge Journal Watch , Dr. Sharma reviews 11 important new studies shaping modern cardiac electrophysiology, arrhythmia care, and cardiovascular risk management. This March 2026 issue covers intravenous amiodarone in preexcited atrial fibrillation , the NURSECAT-AF randomized trial of nurse-led care after AF ablation , left bundle branch area antitachycardia pacing vs right ven...

EP Edge™ Journal Watch Issue 15: PFA Recurrence, Bayesian AF Ablation, Non-PV Triggers, Diltiazem-DOAC Risk, and Stroke Prevention After AF Ablation 16.03.2026

In EP Edge™ Journal Watch Issue 15 , Dr. Niraj Sharma reviews some of the most important new studies in electrophysiology and atrial fibrillation management from March 2026. This episode explores whether early recurrence after pulsed field ablation (PFA) should still be viewed as part of a traditional blanking period or whether it may represent an early marker of later treatment failure. It also e...

EP Edge Journal Watch #14 (March 2026): AF Ablation at the Extremes: Octogenarians, HFrEF PVI-Only, LAAC, PFA Hemolysis/AKI & Redo Timing 09.03.2026

In EP Edge Journal Watch Issue 14 (March 2026) , Dr. Niraj Sharma breaks down the most clinically “edge-case” decisions in contemporary electrophysiology—where ablation strategy, stroke prevention, and safety monitoring collide. This episode covers: AF ablation in octogenarians (REHEALTH AF): why the signal may be less about short-term hard outcomes and more about symptoms, function, and patient-c...

EP Edge Journal Watch Issue 13 (March 2026): Ultrashort AF, ILR Accuracy, Semaglutide + Ablation, PADIT, PCOS, LBBAP and Next-Gen nanosecond PFA (SCENA-AF) 02.03.2026

EP Edge Journal Watch — Issue 13 (March 2026) explores a core 2026 EP problem: signal detection (wearables, patches, ILRs) and energy delivery (next-gen PFA) are advancing faster than the clinical rules we use to interpret risk and outcomes .  In this episode, Dr. Niraj Sharma breaks down what’s clinically actionable, what’s methodologically fragile, and what should change practice now versus what...

EP Edge™ Journal Watch: February 2026 Issue 12: AF Ablation “Success” Reframed: ADVENT-LTO 4-Year PFA Durability, 20-Year PVI Outcomes, Monitoring Rules, CIED Risks & PICM 23.02.2026

 In this episode of EP Edge™ Journal Watch (Issue 12, February 2026) , Dr. Niraj Sharma breaks down a deceptively simple question in atrial fibrillation (AF) ablation: what does “success” actually mean—at 1 year, 4 years, and 20 years? We start with ADVENT-LTO , the long-term extension of the randomized ADVENT trial, examining 4-year outcomes of pulse field ablation (PFA) vs thermal ablation —and...

EP Edge™ Journal Watch (Special Edition): Feb 2026 HRS/EHRA Pulsed Field Ablation (PFA) Scientific Statement — Vote Counts, Safety Signals, and Real-World Workflow 19.02.2026

In this EP Edge™ Journal Watch Special Edition, we unpack the newly released 2026 HRS/EHRA Scientific Statement on Pulsed Field Ablation (PFA) and translate “consensus language” into practical, lab-ready decision-making . This isn’t a surface summary—it’s a critical appraisal of how the statement was built (including the 11-voter model ), where the field is truly aligned, and where recommendations...

EP Edge Journal Watch Issue 11 February 2026: Varipulse Safety Signal, ElectroPulse PFA, Farapoint CTI Ablation, Leadless Pacemaker Infection & EP Occupational Hazards 16.02.2026

In this episode of EP Edge Journal Watch , we review several developments that directly impact modern electrophysiology practice — from pulsed field ablation safety to operator health. We begin with the real-world Varipulse experience, where early neurovascular events dropped dramatically after workflow modification and reduction of lesion stacking, highlighting that PFA success depends as much on...

EP Edge Journal Watch Issue 10, February 2026: Pulsed Field Ablation Durability, AF Ablation Outcomes, Wearable AF Detection, ICD and VT Insights 09.02.2026

EP Edge Journal Watch: Feb 2026 Issue 10 In this episode of EP Edge Journal Watch , we examine the latest developments shaping the future of cardiac electrophysiology , with a focus on pulsed field ablation durability, atrial fibrillation ablation outcomes, wearable AF detection, ventricular tachycardia ablation endpoints, autonomic modulation, and ICD patient outcomes . Pulsed field ablation has...

EP Edge Journal Watch Special Edition: VOLT IDE One-Year Results in Context: ADVENT, ADVANTAGE-AF, AdmIRE, SPHERE-Per-AF & U.S. PFA Pivotal Trials 06.02.2026

Pulsed field ablation (PFA) has rapidly reshaped atrial fibrillation ablation, but true clinical validation depends on durable one-year outcomes, not early feasibility or acute safety alone . In this EP Edge Journal Watch Special Edition , Dr. Niraj Sharma delivers a comprehensive, system-level analysis of the Abbott VOLT IDE one-year data , now completing the 12-month efficacy and safety landscap...

EP Edge Journal Watch — Issue 9 Redefining Ventricular Tachycardia Care: From Noninvasive Radioablation to Leadless, Modular, and Drug-Based Strategies 02.02.2026

In EP Edge Journal Watch – Issue 9 (February 2026) , we take a comprehensive, clinically grounded look at the evolving management of ventricular tachycardia (VT) —from last-line noninvasive therapies to next-generation devices, pharmacologic strategy, and infection prevention. This episode critically reviews the STRA-MI-VT trial , examining stereotactic arrhythmia radioablation (STAR) for refracto...

EP Edge Journal Watch – Issue 8 (2026): VT Storm Outcomes, Inappropriate ICD Shocks, AF Ablation Modifiers, and the Rise of Patient-Directed SVT Care 26.01.2026

In EP Edge Journal Watch – Issue 8 (2026) , we deliver a comprehensive, evidence-driven analysis of the most important and practice-shaping studies in contemporary cardiac electrophysiology. This episode begins with ventricular tachycardia storm, examining why in-hospital mortality remains high despite aggressive rhythm control. We break down the CHAMPS score, focusing on patient selection, system...

EP-EDGE Journal Watch #7: Direct Oral Anti-Coagulant Adherence, AF Risk Stressors, ns-PFA Safety & EP Device Updates 19.01.2026

EP-EDGE Journal Watch – Issue 7 (January 2026) Advanced Cardiac Electrophysiology Podcast | AF, DOACs, PFA, Devices & Heart Failure In EP-EDGE Journal Watch Issue 7 , Dr. Niraj Sharma delivers a high-impact, clinician-focused breakdown of the most practice-changing cardiac electrophysiology studies published in late 2025 and early 2026. This episode moves beyond headlines to translate data int...

LAAO vs Anticoagulation Explained: WATCHMAN FLX, AF Ablation Recurrence, Post-TAVR Heart Block & ICU AF, Hormones and TdP – EP Edge Journal Watch 12.01.2026

EP Edge Journal Watch Podcast — Issue 6 (January 2026) Left Atrial Appendage Occlusion, AF Ablation Insights, Post-TAVR Conduction, ICU Anticoagulation & Translational EP Signals EP Edge Journal Watch is your high-yield, evidence-driven electrophysiology podcast—designed for busy clinicians who want clinical relevance, mechanistic insight, and practice-changing nuance without wading through ev...

Pulsed Field Ablation, Atrial Fibrillation Progression & Leadless Pacing | EP Edge Journal Watch – Jan 2026 (Issue 5) 05.01.2026

EP Edge Journal Watch — January 2026 | Issue #5 Pulsed Field Ablation, Device Therapy, and the Era of Personalized EP Welcome to EP Edge Journal Watch – Issue #5 (January 2026) , your high-yield, evidence-driven electrophysiology podcast designed for practicing EPs who want more than just abstracts. As 2026 begins, electrophysiology is entering a defining phase—where pulsed field ablation (PFA) ma...

AF Beyond the Lesion: Can We Stop Anticoagulation, Trust Sham Trials, and Treat AF as a Metabolic Disease? 18.12.2025

In this December 2025 episode of EP Edge Journal Watch , Dr. Niraj Sharma breaks down the most provocative atrial fibrillation trials of the year—studies that force us to rethink what really drives AF outcomes beyond the ablation lesion   EP EDGE JW Dec 2025 Newsletter. We dive deep into four game-changing themes shaping modern electrophysiology: Can we safely stop anticoagulation after AF ablatio...

EP Edge Journal Watch Issue 3: Smartwatch AFib Detection: Accuracy, False Alerts, Apple Watch ECG, and What Clinicians Need to Know 30.11.2025

Smartwatches are now among the most widely used heart-monitoring tools in the world — but how accurate are they really at detecting AFib? In this December 2025 Issue 3 of EP-Edge Journal Watch , Dr. Niraj Sharma, cardiologist and cardiac electrophysiologist, breaks down the strongest evidence to date on smartwatch AFib detection , Apple Watch ECG performance , false alerts , AF burden tracking , a...

EP Edge Journal Watch: Critical Analysis: AQUATIC Trial — AF + CAD: Impact on Antithrombotic Strategy (NEJM October 2025) 10.11.2025

In this special EP Edge Journal Watch episode, Dr. Niraj Sharma delivers a critical analysis of the landmark AQUATIC Trial , published in the New England Journal of Medicine (October 2025) . This pivotal study explores optimal antithrombotic strategies in patients with atrial fibrillation (AF) and coronary artery disease (CAD) — balancing ischemic protection with bleeding risk. Dr. Sharma dissects...

EP Edge Journal Watch — November 2025, Edition 2: From Lifestyle to Lifeline 02.11.2025

In this episode, Dr. Niraj Sharma breaks down six pivotal studies shaping today’s electrophysiology and cardiology practice—from lifestyle-driven AF control (ARREST-AF) and post-CABG atrial fibrillation management to the DOAC + aspirin conundrum in stable CAD, the return of digitoxin in HFrEF, insights from CABANA-Substudy, and the latest ICD registry data on shock rates. 

EP Edge Journal Watch | Episode 1, November 2025: Potassium and VT, GDMT Withdrawal & AF Risk Uncovered 30.10.2025

In this inaugural episode, Dr. Niraj Sharma breaks down three pivotal studies that could shift daily EP practice: How high-normal potassium targeting can reduce VT burden ( POT-CAST trial ). When GDMT withdrawal may be safe after recovery from tachycardia-induced cardiomyopathy. Why adverse pregnancy outcomes may predict long-term AF risk. Get the signal — not the noise — with expert analysis, cli...

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