CARTA - Anthropogeny (Video)

Ajit Varki, Distinguished Professor in the Departments of Medicine and Cellular & Molecular Medicine, Co-Director of CARTA, and Co-Director of the Glycobiology Research and Training Center at the University of California, San Diego, focuses on a family of cell surface sugars called the sialic acids, and their roles in biology, evolution and disease. Series: "CARTA - Center for Academic Research an...

Genevieve Konopka is an Assistant Professor of Neuroscience at UT Southwestern Medical Center. The focus of her research is elucidating how developmental signaling pathways are disrupted in neuropsychiatric illnesses, and identifying human-specific pathways that are vulnerable to neuropsychiatric disease. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show I...

Yoav Gilad is Associate Professor of Human Genetics at the University of Chicago. He studies genetic and regulatory differences between humans and our close evolutionary relatives, with the long-term goal of identifying the genetic basis for human-specific traits, including genetic variation that underlies higher susceptibility to certain diseases and disorders in humans than in other primates. Se...

Katherine Pollard, Associate Investigator at the Gladstone Institutes and Associate Professor of Biostatistics at UC San Francisco, specializes in evolutionary genomics, in particular identifying genome sequences that differ significantly between or within species and their relationship to biomedical traits. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Sho...

Alysson Muotri, Assistant Professor at UC San Diego, focuses on human brain development and evolution, exploring mobile elements as generators of neuronal diversity. He is also interested in modeling neurological diseases using human induced pluripotent stem cells. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21983]

Evan Eichler is an Associate Professor of Genome Sciences at the University of Washington. The long-term goal of his research is to understand the evolution, pathology and mechanisms of recent gene duplication and DNA transposition within the human genome. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21982]

Richard “Ed” Green, Assistant Professor of Biomolecular Engineering at UC Santa Cruz, explains how and what we know about our relation to Neandertal Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21981]

Elaine Mardis, Associate Professor of Genetics at Washington University and Senior Research Scientist at Bio-Rad Laboratories, explores the orangutan genome. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21980]

Peter Richerson, Distinguished Professor Emeritus in the Department of Environmental Science and Policy at the University of California, Davis, focuses on the processes of cultural evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Show ID: 21289]

Donald Pfaff, head of the Laboratory of Neurobiology and Behavior at The Rockefeller University, upends our entire understanding of ethics and social contracts with an intriguing proposition: the Golden Rule is hardwired into the human brain. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Show ID: 21288]

Sarah Hrdy is currently professor emerita at the University of California, Davis. She is a renowned anthropologist and primate sociobiologist who seeks to understand, step by Darwinian step, how apes could have evolved to imagine and care about what the lives of others might be like. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21286]

Peter Hammerstein is a theoretical biologist at the Humboldt University in Berlin, Germany. Given his background in game theory and economics, he is interested in conflict and cooperation at the level of individuals and of genes. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21285]

Steve Frank is Professor of Ecology and Evolutionary Biology at the University of California, Irvine. One of his current research projects is centered on microbial life history and sociality. The theory of virulence is an example of the broader problems of sociality and life history. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21284]

Patricia Smith Churchland is Professor of Philosophy at UC San Diego. The central focus of her research has been the exploration and development of the hypothesis that the mind is the brain. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 21283]

Christophe Boesch is Director of Primatology at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. His research takes an inclusive approach, addressing the biology of chimpanzees from many viewpoints and applying this knowledge to our understanding of the evolution of cognitive and cultural abilities in humans. Series: "CARTA - Center for Academic Research and Training in...

Christopher Boehm is Professor of Biological Sciences & Anthropology and Director of the Goodall Research Center at the University of Southern California. He is a cultural anthropologist with a subspecialty in primatology, who researches conflict resolution, altruism, moral origins, and feuding and warfare. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show...

Closing remarks for CARTA’s Evolutionary Origins of Art and Aesthetics symposium held in March 2009. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Show ID: 16440]

Humans live in a world of ideas—born in the brain, shared through language, accumulated in culture across generations, and made reality. From the first flaked stone tools to the building of shelters, from figurative and symbolic art to abstract thought, our brains are engines of imagination—an “idea organ” that has transformed both our species and the planet itself. The distinct biology of the hum...

The extraordinary abilities of the cerebral cortex are central to what sets humans apart from other species. A defining feature of the cortex is its organization along a sensorimotor-to-association (S–A) axis, extending from primary sensorimotor areas to transmodal association regions that support abstract cognition. This axis varies across species and has been profoundly remodeled in humans. Nena...

Human brain expansion is often discussed in terms of the genetic and molecular innovations that drove uniquely human cognitive abilities. Yet evolution is fundamentally a process of tradeoffs. Disproportionate expansion of forebrain structures increases the demands placed on long-range connectivity, metabolism, and cellular maintenance, imposing costs that scale with brain size. Alex Pollen, assoc...

Dr. Bruce Miller, director of the UCSF Edward and Pearl Fein Memory and Aging Center, examines what neurodegenerative disease reveals about the neural basis of creativity and the social mind. Research in frontotemporal dementia (FTD) shows that visual creativity is not rare: a subset of patients—particularly those with left anterior temporal degeneration—develop new or intensified artistic abiliti...

From stone tools and shelters to symbolic art and abstract thought, human history is shaped by a brain built to form and share ideas. Joseph Paradiso, Professor in Media Arts and Sciences at the MIT Media Lab, explores what comes next after the early visions of ubiquitous computing have largely arrived in today’s Internet of Things world, where low-power sensors and interfaces are embedded in smar...

A fundamental question in biology is: how did humans acquire their unique characteristics? What allows us to stand upright, while our primate ancestors walked on all fours? What brain alterations drove our increased intelligence and allowed us to perceive our own mortality? One of the mechanisms that has been hypothesized to be involved is changes in gene expression elicited by nucleotide alterati...

Humans excel at transmitting ideas, skills, and knowledge across generations, and at building on those competencies in a cumulative manner. James Rilling, Professor of Psychology at Emory University, explores how the transmission of our cumulative culture is assumed to depend on both language and mental perspective-taking, or theory of mind. If humans have specialized abilities in these domains, w...

The distinct biology of the human brain, scaffolded by language and culture, allows ideas to be formed, named, shared, and accumulated across generations. Dean Falk, Professor of Anthropology, Florida State University, explains how paleoneurologists study the brains of human ancestors by producing endocasts from fossilized skulls and measuring cranial capacities. Dated skulls indicate brain size m...