Base by Base - Music

This release contains only the music track from Base by Base Episode 388. Song title: Borrowed Time, Brand-New Liver Original Base by Base episode: 388: Base by Base | Episode 388 — In situ CAR‑macrophage alleviates liver fibrosis Article metadata: Article title: mRNA‑laden LNP‑enabled in situ CAR‑macrophage alleviates liver fibrosis via inhibiting activated HSCs and modulating the immune microenv...

This release contains only the music track from Base by Base Episode 387. Song title: When the Shield Gets Thin Original Base by Base episode: 387: Homotypic Dengue Reinfections and Long-Term Antibody Decay Article metadata: Article title: Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus Journal: PNAS DOI: 10.1073/pnas.2606206123 Reference: Andrade...

This release contains only the music track from Base by Base Episode 386. Song title: Double the Light Original Base by Base episode: 386: Genome Doubling and the Bioeconomy Article metadata: Article title: Polyploidy: A macromutational force pushing bioeconomic developments Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.2522065123 Reference: Peeters MKR & Va...

This release contains only the music track from Base by Base Episode 385. Song title: Double the Light, Double the Shadow Original Base by Base episode: 385: Growth under Pressure: Polyploidy Induced by Stress Article metadata: Article title: Growth under pressure: The pros and cons of polyploidy induced by stress Journal: PNAS DOI: 10.1073/pnas.2522063123 Reference: Sarabia Olivera L, Belato PB,...

This release contains only the music track from Base by Base Episode 384. Song title: CisR on the Switch Original Base by Base episode: 384: RNA Brake on Cholera Phage: CisR Controls CTXϕ Article metadata: Article title: A 3’UTR-derived small RNA modulates the life cycle of the cholera toxin–encoding filamentous phage, CTXϕ Journal: PNAS DOI: 10.1073/pnas.2535142123 Reference: Haycocks JRJ, O’Dris...

This release contains only the music track from Base by Base Episode 383. Song title: Trans Signals in the Bloodlight Original Base by Base episode: 383: Genetics of the Circulating Proteome: pQTLs, Pathways, and Disease Links Article metadata: Article title: Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome Journal: Cell DOI: 10.1016/j.cell.2026.03.049 R...

This release contains only the music track from Base by Base Episode 382. Song title: Old Codes, New Blood Original Base by Base episode: 382: How animal blood cells evolved from unicellular ancestors Article metadata: Article title: Animals have expanded the evolutionary legacy of unicellular ancestors in blood cells Journal: PNAS DOI: 10.1073/pnas.2528110123 Reference: Nagahata Y, Ishidae T, Sat...

This release contains only the music track from Base by Base Episode 381. Song title: Light Writes the Map Original Base by Base episode: 381: Light-written spatial barcodes enable tunable multiomic sequencing (BALI) Article metadata: Article title: Spatially tuneable multiomic sequencing using light-driven combinatorial barcoding of molecules in tissues Journal: PNAS DOI: 10.1073/pnas.2527896123...

This release contains only the music track from Base by Base Episode 380. Song title: Barcode the Breakthrough Original Base by Base episode: 380: Prime-SGE maps drug-resistance variants at scale Article metadata: Article title: A multiplex, prime editing framework for identifying drug resistance variants at scale Journal: Cell Genomics DOI: 10.1016/j.xgen.2026.101167 Reference: Abadie FMC, Suiter...

This release contains only the music track from Base by Base Episode 379. Song title: Long Reads, Clearer Roads Original Base by Base episode: 379: Long reads reveal hidden structural and repeat variation in autism Article metadata: Article title: Long-read genome sequencing improves detection and functional interpretation of structural and repeat variants in autism Journal: Cell Genomics DOI: htt...

This release contains only the music track from Base by Base Episode 378. Song title: Assembly Line of Light Original Base by Base episode: 378: Dominant-negative PSMB8 variants stall immunoproteasome assembly Article metadata: Article title: Monoallelic PSMB8 variants cause PRAAS with immunodeficiency through impaired immunoproteasome assembly Journal: The American Journal of Human Genetics DOI:...

This release contains only the music track from Base by Base Episode 377. Song title: Attention Turns to Steel Original Base by Base episode: 377: ProteomeLM — proteome-scale language modeling for interactomes and essential genes Article metadata: Article title: ProteomeLM: A proteome-scale language model enables accurate and rapid prediction of protein–protein interactions and gene essentiality a...

This release contains only the music track from Base by Base Episode 376. Song title: Slide Back, Strike Again Original Base by Base episode: 376: Pfh1's Balancing Act: Unwinding, Rewinding, and the Role of Mitochondrial SSB Article metadata: Article title: Regulation of Pfh1 helicase activity by nucleic acid interactions and mitochondrial SSB Journal: Proceedings of the National Academy of Scienc...

This release contains only the music track from Base by Base Episode 375. Song title: Wired for the Light Original Base by Base episode: 375: Biallelic DSCAM LoF: a syndromic NDD with nystagmus and cone-pathway retinal dysfunction Article metadata: Article title: Biallelic loss-of-function variants in DSCAM cause a neurodevelopmental syndrome with nystagmus and retinal dysfunction Journal: Human G...

This release contains only the music track from Base by Base Episode 374. Song title: DNA Keys, RNA Doors Original Base by Base episode: 374: DNA-guided Cas12a reprogrammed to target RNA Article metadata: Article title: DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage Journal: Nature Biotechnology DOI: 10.1038/s41587-026-03120-5 Reference: Wu X., Lam W.H., Zhao Z.,...

This release contains only the music track from Base by Base Episode 373. Song title: Stop Signs Turn to Lyrics Original Base by Base episode: 373: Base by Base 373 — A ciliate rewrites UAA and UAG Article metadata: Article title: Identification of a non-canonical ciliate nuclear genetic code where UAA and UAG code for different amino acids Journal: PLOS Genetics DOI: https://doi.org/10.1371/journ...

This release contains only the music track from Base by Base Episode 372. Song title: Threads That Pull Us Forward Original Base by Base episode: 372: Genes, IQ and Socioeconomic Outcomes in Emerging Adults Article metadata: Article title: Longitudinal associations between cognitive ability and socioeconomic status are partially genetic in nature Journal: Scientific Reports DOI: 10.1038/s41598-026...

This release contains only the music track from Base by Base Episode 371. Song title: Open the Switches in the Dark Original Base by Base episode: 371: Glial epigenomic dysregulation and genetic risk in tauopathies Article metadata: Article title: Single-nucleus epigenomic dysregulation unmasks genetic risk-associated neurodegenerative glia states Journal: Nature Communications DOI: 10.1038/s41467...

This release contains only the music track from Base by Base Episode 370. Song title: Methyl to the Membrane Original Base by Base episode: 370: ICMT and INPP5E enable BRAFV600E tumor growth Article metadata: Article title: ICMT supports BRAF V600E -driven tumor growth by membrane targeting of the CAAX protein INPP5E Journal: Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.260179...

This release contains only the music track from Base by Base Episode 369. Song title: Break the Efflux Original Base by Base episode: 369: NEK2 drives EBV-positive NHL pathogenesis Article metadata: Article title: NEK2 drives pathogenesis, drug resistance, and LMP1 expression in EBV-positive non-Hodgkin lymphoma Journal: PNAS DOI: 10.1073/pnas.2535550123 Reference: White MC, Lange PT, Stewart J, D...

This release contains only the music track from Base by Base Episode 368. Song title: Cut the Static, Save the Signal Original Base by Base episode: 368: PARP1 and Amyloid: Protecting Neurons in a Familial AD Model Article metadata: Article title: PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease model Journal: PNAS DOI: 10.107...

This release contains only the music track from Base by Base Episode 367. Song title: Old Notes, New Bites Original Base by Base episode: 367: Ancestral Splice Variation Fuels Cichlid Jaw Diversification Article metadata: Article title: Ancestral splice variation is a key substrate for rapid diversification in African cichlids Journal: PNAS DOI: 10.1073/pnas.2516477123 Reference: Singh P., Ahi E.P...

This release contains only the music track from Base by Base Episode 366. Song title: Circle in the Static Original Base by Base episode: 366: BRCA1P1 suppresses antiviral and antitumor immunity Article metadata: Article title: Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.25...

This release contains only the music track from Base by Base Episode 366. Song title: Circle in the Static Original Base by Base episode: 366: BRCA1P1 suppresses antiviral and antitumor immunity Article metadata: Article title: Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.25...

This release contains only the music track from Base by Base Episode 365. Song title: Pocket Full of Proof Original Base by Base episode: 365: MEN1 mutations and menin inhibitor resistance Article metadata: Article title: CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials Journal: Nature Communications DOI: 10.1038/s41467-026-72685-1 Re...