The Dr. Hyman Show

For decades, we've thought about conditions like Alzheimer's disease, depression, and Parkinson's disease as disorders of the brain. But what if that's only part of the story? Emerging science is revealing that many of the factors driving cognitive decline, mental illness, and neurodegenerative disease may begin far outside the brain itself—in our metabolism, our immune system, our gut microbiome,...

You've cleaned up your diet. You're taking the supplements. You're exercising, sleeping more, and doing everything "right." So why do you still feel exhausted, inflamed, anxious, or stuck? In this encore episode—one of the most impactful Office Hours conversations we've shared—I explore a question that could change the way you think about healing: What if your nervous system is the missing piece?...

As part of our summer series, we're revisiting some of the most important conversations we've had on the topics that matter most to our health. And few are more important than heart disease. Heart disease remains the number one cause of death worldwide. Yet despite decades of research, millions of prescriptions, and billions of dollars spent on treatment, many people are still confused about what...

High cholesterol has been treated as the main cause of heart disease for decades. But over the years, I've changed my mind. Today, I believe cholesterol is only part of the story, and that inflammation, insulin resistance, and metabolic health are often the real drivers of cardiovascular disease. In this encore episode, I'm revisiting one of my most talked-about Office Hours conversations to share...

Most health issues don't appear overnight. Long before a diagnosis is made, the body often provides subtle clues that something needs closer attention. On this episode of The Dr. Hyman Show, I talk with double board-certified fertility physician Dr. Natalie Crawford about her new book, The Fertility Formula, and why fertility and hormone health can reveal far more about your health than many peopl...

Bloating, brain fog, fatigue, skin issues, food sensitivities, autoimmune symptoms—most people treat these as separate problems. But often, they can all trace back to the same place: the gut. And the surprising part is that you don't need digestive symptoms to have gut dysfunction. Because your gut isn't just responsible for digestion—it's deeply connected to your immune system, hormones, metaboli...

We’ve been taught to treat chronic diseases as isolated problems to be diagnosed and managed. But these conditions may have more in common than conventional medicine has traditionally recognized. On this episode of The Dr. Hyman Show, I’m joined by physician and researcher Dr. Terry Wahls, who transformed her understanding of disease after developing progressive multiple sclerosis. We discuss the...

Mold is one of the most misunderstood topics in health. Some people are told it’s not a real problem. Others are led to believe it’s the cause of every symptom they have. The truth lies somewhere in the middle. While not everyone exposed to mold gets sick, chronic exposure to water-damaged environments can contribute to fatigue, brain fog, anxiety, sinus issues, immune dysfunction, hormone imbalan...

If we're wired for joy, why do so many successful people feel exhausted, disconnected, or emotionally flat? On this episode of The Dr. Hyman Show, I sit down with psychiatrist, researcher, and author Dr. Judith Joseph, whose team conducted the first peer-reviewed clinical study on high-functioning depression. We talk about why feeling "fine" on the outside doesn't always reflect what's happening b...

High cholesterol is one of the most common reasons people are told they’re at risk for heart disease. But what if cholesterol isn’t the root problem? What if it’s actually a signal of deeper metabolic dysfunction—and focusing on the number alone causes us to miss what’s really driving cardiovascular risk? In today’s episode, we explore a functional medicine approach to cholesterol and heart health...

Depression is often treated as a single condition. But two people with the same diagnosis can have completely different underlying causes. On this episode of The Dr. Hyman Show, I’m rejoined by Dr. James Greenblatt to explore why depression may be less of a disease and more of a signal that something deeper is going on. We discuss how a root-cause approach can uncover what’s driving symptoms and w...

Morning routines have become one of the most talked-about topics in health and wellness—but it’s not just about productivity or checking boxes. How you start your morning has a direct biological impact on your brain, your energy, your metabolism, and even how well you sleep at night. Yet, so many people inadvertently sabotage their biology first thing in the morning with dopamine hits, sugar, and...

For far too long, many women have been told their symptoms were normal, exaggerated, or simply something they had to live with—treated as isolated problems instead of part of a much larger hormonal transition happening inside the body. On this episode of The Dr. Hyman Show, I’m joined by Dr. Sharon Malone, host of The Second Opinion podcast and Chief Medical Advisor at Alloy Women’s Health. We dis...

Hormone replacement therapy is one of the most talked about—and misunderstood—topics in women’s health. For years, women were told HRT was dangerous. Now, the conversation is shifting, but many are still left confused about what’s actually safe, when to start, and whether hormones are even right for them. In today’s episode, I’m joined by Dr. Cindy Geyer from my clinic, The UltraWellness Center, t...

We’re surrounded by plastics and environmental chemicals every day, but only recently have scientists begun to understand how deeply they may be affecting human health. On this episode of The Dr. Hyman Show, I sit down with Dr. Shanna Swan to explore what the latest science reveals about plastics, fertility, hormone health, and the everyday habits that may be shaping our biology more than we reali...

Hydration affects far more than thirst. Even mild dehydration can impact your focus, memory, mood, energy, and overall brain performance—yet most people walk through the day without realizing they’re under-hydrated. The problem isn’t just not drinking enough water. It’s also caffeine overload, low electrolytes, processed foods, and inconsistent habits that quietly leave your brain and body struggl...

Most health and fitness advice for women is based on research done in men. That’s something we need to rethink. On this episode of The Dr. Hyman Show, I sit down with Dr. Stacy Sims, an exercise physiologist and leading researcher in women’s health. Her work has focused on how female physiology actually changes over time—and how training and nutrition need to change with it. Watch the full convers...

Autoimmune disease is often treated as something random, lifelong, and out of your control. But what if it’s not your body malfunctioning—what if it’s your immune system responding exactly the way it’s designed to, to something it sees as a threat? When you understand what’s driving that response, everything changes. Here’s what I cover in today’s episode: • The 5 key drivers—food, toxins, gut hea...

We tend to think of heart disease, cancer, and Alzheimer’s as separate problems. But what if they all stem from the same underlying process? On this episode of The Dr. Hyman Show, I sit down with Dr. Eric Verdin, whose research, including work on compounds like urolithin A, is helping reshape how we think about aging and long-term health. We explore why aging may be the biggest driver of chronic d...

Migraines aren’t just headaches and if you’ve ever had one, you know how debilitating they can be. But they’re not random, and they’re not just genetic. Migraines are a signal that something deeper is out of balance in your body and if you only treat the symptoms, you miss the real opportunity to prevent them. In this episode, I break down what’s really driving migraines, including: • The root cau...

It’s easy to think of mental health as something happening only in the brain. But more and more, we’re seeing how closely it’s tied to what’s going on in the gut. Today, I’m joined again by Dr. William Li, a New York Times bestselling author. We discuss his latest book, Eat to Beat Your Diet, and how food, inflammation, and microbiome shape the way we think and feel. Watch the full conversation on...

Most parents are doing their best but the modern food environment is working against them. Between ultra-processed foods, constant marketing, and confusing nutrition advice, it’s easy to feel overwhelmed. But what your child eats doesn’t just affect their growth—it shapes their brain, immune system, metabolism, and long-term health. In this episode, we break down what actually matters and how to a...

Most of medicine is built around snapshots. You feel something, you test for it, and by the time you find it, you’re already behind. But what if the problem isn’t the test—it’s how we use it? In this episode, I sit down with physicist and imaging pioneer Dr. Daniel Sodickson, Chief Medical Scientist at Function Health and author of The Future of Seeing. We break down why tools like MRI are shiftin...

Sleep is one of the most important and most overlooked drivers of your health. If you’re struggling to fall asleep, waking up at 2–4am, or getting a full night’s sleep but still feeling exhausted, your body is trying to tell you something. Poor sleep isn’t just about habits, it’s a signal that key systems like your nervous system, blood sugar, hormones, or circadian rhythm are out of sync. In this...

What if feeling better didn’t have to take months or years to figure out, but could start today? On this episode of The Dr. Hyman Show, I sit down with Dr. Scott Sherr to talk about why so many people feel stuck in what he calls a “sympathetic spiral of doom.” Energy is low, recovery isn’t what it used to be, and there’s a constant sense of stress that doesn’t seem to resolve. We walk through what...