Neurology Minute

In the fourth episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss the use of dexamethasone in the treatment of pneumococcal meningitis.

In the first installment of this series, Dr. Aaron Zelikovich and Dr. Bhaskar Roy  discuss how emerging treatments for myasthenia gravis compare   to one another.  Show citation:  McLaren NP, Rosati M, Zhong W, et al. Comparison of the Efficacy and Safety of Myasthenia Gravis Treatments: A Bayesian Network Meta-Analysis.  Neurology . 2026;107(3):e218351. doi: 10.1212/WNL.0000000000218351   

Dr. Jason Crowell and Ka-Ho Wong discuss national trends in Medicare reimbursement for inpatient neurologic care.  Show citation:  Wong KH, Castillo M, King J, et al. National Trends in Medicare Charges and Reimbursement for Inpatient Neurologic Care, 2013-2023. Neurology. 2026;107(6):e218460. doi: 10.1212/WNL.0000000000218460 

In the third episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss HSV encephalitis and dexamethasone. 

In part two of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss pegivirus-associated encephalomyelitis. 

In part one of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss acute necrotizing encephalopathy.

In part one of this series, Drs. Greg Cooper, Trey Bateman, and Gregg Day discussed key takeaways from the 2026 Alzheimer's Association International Conference, focusing on blood-based biomarkers, anti-amyloid therapies, and other important highlights.      

Dr. Justin Abbatemarco recaps a presentation on Hashimoto encephalopathy from the AAN Autoimmune Neurology Conference.   Show citation:    Valencia-Sanchez C, Pittock SJ, Mead-Harvey C, et al. Brain dysfunction and thyroid antibodies: autoimmune diagnosis and misdiagnosis. Brain Commun. 2021;3(2):fcaa233. Published 2021 Jan 5. doi: 10.1093/braincomms/fcaa233     Brain, Jellinek E, Ball K HASHIMOTO...

In this lab minute, Dr. Stacey Clardy reviews the role of vitamin B12 testing in neurologic practice. 

In part two of this series, Dr. Dara Albert and Dr. Daniel Freedman discuss key unanswered questions in infantile epilepsy and future research priorities.  Show citation:  Freedman D, Babatunde I, Morgan RL, et al. American Epilepsy Society Clinical Practice Guideline: Infantile Epilepsy.  Epilepsy Curr . 2026;26(3):174-202. Published 2026 Apr 8. doi: 10.1177/15357597261433266  

Dr. Shuvro Roy and Prof. Catherine Jutzeler discussed how age influences neurologic and functional recovery after spinal cord injury and how these findings could inform treatment and future clinical trials.  Show citation:  Pavese C, Scivoletto G, Puci M, et al. The Relationship Between Age and Recovery After Spinal Cord Injury: A Longitudinal Cohort Study.  Neurology . 2026;106(2):e214516. doi: 1...

Dr. Greg Cooper and Dr. Chloe Hill discuss comparing virtual and in-person neurology outpatient visits for new patients. Show citation:  Hill CE, Lin CC, Harris A, et al. Virtual vs In-Person Neurologic Ambulatory Care: A Case-Control Study of Subsequent Health Care Utilization.  Neurology . 2026;106(10):e214989. doi: 10.1212/WNL.0000000000214989  

In this lab minute, Dr. Stacey Clardy discusses Tolosa Hunt syndrome

Dr. Margarita Fedorova talks with Dr. Sunanjay Bajaj about the Consortium of Neurology Residents and Fellows (CNRF).  Visit the AAN website to learn more about the CNRF .  Connect with the  AAN's Consortium of Neurology Residents and Fellows on Synapse . 

Dr. Aaron Zelikovich discusses the efficacy and anthropometric effect of vamorolone with prednisone and deflazacort. Show citation:  Clemens PR, Berglund A, Schiava M, et al. Vamorolone for Duchenne Muscular Dystrophy: A Cross-Trial Efficacy Comparison With Classic Corticosteroids From the FOR-DMD Trial.  Neurology . 2026;107(1):e214756. doi: 10.1212/WNL.0000000000214756  

In part one of this series, Dr. Dara Albert and Dr. Daniel Freedman share their key takeaways from the recent guideline. Show citation:  Freedman D, Babatunde I, Morgan RL, et al. American Epilepsy Society Clinical Practice Guideline: Infantile Epilepsy.  Epilepsy Curr . 2026;26(3):174-202. Published 2026 Apr 8. doi: 10.1177/15357597261433266   

Dr. Jessica Ailani and Dr. Serena Orr discuss the genetic risk of migraine and post-traumatic headache in children.  Show citation:  Orr SL, Hershey AD, Kurowski BG, et al. Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study. Neurol Genet. 2026;12(2):e200371. Published 2026 Apr 1. doi: 10.1212/NXG.0000000000200371  

Dr. Aaron S. Zelikovich discusses the phase 3 NIMBLE trial of cemdisiran, an siRNA targeting complement component 5, for the treatment of generalized myasthenia gravis.  Show citation:  Vu T, Habib AA, Jacob S, et al. Efficacy and safety of cemdisiran siRNA in myasthenia gravis (NIMBLE): a double-blind, randomised, placebo-controlled, phase 3 trial.  Lancet . 2026;407(10540):1712-1725. doi: 10.101...

Dr. Zohaib Siddiqi shares clinical pearls on negative myoclonus. 

Dr. Margarita Fedorova discusses the use of troriluzole for spinocerebellar ataxia.  Show citations:  https://www.neurology.org/doi/10.1212/WNL.0000000000209018   https://clinicaltrials.gov/study/NCT06034886   https://clinicaltrials.gov/study/NCT02960893  

Drs. Paul Crane, Fiifi Duodu, and Malya Sahu discuss neuroimmunology and multiple sclerosis diagnosis in Africa, including challenges and efforts to improve care.  Show citation:  Sahu M, Chomba M, Duodu F, Diaz MM, Sokhi D, Saylor D. The Current State of Diagnostics for Neuroimmunological Disorders in Africa.  J Cent Nerv Syst Dis . 2025;17:11795735251385319. Published 2025 Nov 19. doi: 10.1177/1...

Dr. Elizabeth Coon and Dr. Lucy Norcliffe-Kaufmann discuss the mechanism-based therapy with ampreloxetine for neurogenic orthostatic hypotension in multiple system atrophy, highlighting recent clinical trial results and future directions.  Show citation:  Freeman R, Kaufmann H, Biaggioni I, et al. Mechanism-Based Therapy With Ampreloxetine for Neurogenic Orthostatic Hypotension in Multiple System...

Dr. Margarita Fedorova explores sex-related differences in the pharmacokinetics of levodopa among levodopa-naïve patients with PD and evaluates their relationships with levodopa-related complications. Show citation:  Conti V, De Bellis E, Corbi G, et al. Sex differences in levodopa pharmacokinetics in early Parkinson's disease: implications on levodopa-related complications.  Front Pharmacol . 202...

In part two of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the steps to take if you are screening for a psychiatric comorbidity and the results indicate that someone may be positive for depression, anxiety, or another condition.  Show citations:  Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults...

In the August episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost highlight how the AAN's growing representation within the AMA strengthens the voice of neurology.  Stay informed by watching the President's Spotlight video .