Dr. B's microbio stuff

Summary videos: https://www.youtube.com/watch?v=5bLEDd-PSTQ https://www.youtube.com/watch?v=Ikq9AcBcohA Kirky Stanford video: https://library.ucsd.edu/dc/object/bb90484996 (best quality video) and a story of its making: https://stanmed.stanford.edu/protein-synthesis-an-epic-on-the-cellular-level/

Recap: https://www.youtube.com/watch?v=Ikq9AcBcohA

Summary siRNA and miRNA https://www.youtube.com/watch?v=cK-OGB1_ELE&t=45s MiRNA https://www.youtube.com/watch?v=5YsTW5i0Xro 2024 review article https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(24)00190-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1471491424001904%3Fshowall%3Dtrue

Lariat splicing https://www.youtube.com/watch?v=CdwLKwseP9Q Spliceosomes https://www.youtube.com/watch?v=YgmoHtLGb5c Spliceosome regulation https://www.youtube.com/watch?v=q63JCoLDR2w

Gal pathway regulation https://www.youtube.com/watch?v=vDWEHlQw6Jk Epigenetic modification, HAT/HDAC https://www.youtube.com/watch?v=eYrQ0EhVCYA

Eukaryotic transcription, RNA polymerases, initiation, core and regulatory promoters. Promoters, enhancers, silencers https://www.youtube.com/watch?v=mK4wzCTrj9k

Long but excellent explanation of the attenuation mechanism starting around minute 12: https://youtu.be/v7L9aCVPEcs?si=F41uin76paXEr0j-

Transcription https://youtu.be/SMtWvDbfHLo?si=m4-1aJ-10r2vIt49 Lac operon https://www.youtube.com/watch?v=h5p05aFzWdA All regulation lac https://www.youtube.com/watch?v=2sMFswbOgKk

Video Cut and paste https://www.youtube.com/watch?v=XYZHMGUGq6o Antibody gene recombination video https://youtu.be/7O87sbbMW7A?si=MAZPjJLPYiq-WdSZ

Different types of DNA damage: UV, ionizing radiations, alkylating agents Repair mechanisms

DNA replication in prokaryotes DNA replication in eukaryotes Videos to watch: https://www.youtube.com/watch?v=oCFN5WUoLRI&t=139s https://www.youtube.com/watch?v=27TxKoFU2Nw https://www.youtube.com/watch?v=62gUb84nWAA

Bacteriophages Animal viruses

Fruitfly, E.coli, and the humble yeast: organisms used for molecular biology and genetics research.

Bacterial vs eukaryotic chromosomes Types of chromatin Brief summary of mitosis/meiosis Nucleosomes: https://www.youtube.com/watch?v=gbSIBhFwQ4s Centromeres and telomeres

Electrophoresis, ultracentrifugation, PCR, restriction enzymes, DNA sequencing, examples of mol bio techniques often used in a lab.

We talk about some general aspects of DNA structure, denaturation, Tm, and renaturation. Helicases, topoisomerases, gyrase. Positive and negative supercoil: https://www.youtube.com/watch?v=5hwaDamU-jo&t=219s Playdoh of DNA coiling https://www.youtube.com/watch?v=3QWA-tFdGN8

Dr. B talks protein structural levels and enzymes. Check out the Foldit game: https://fold.it/

Dr. B talks about amino acids and some protein purification techniques. Check these out: Video about aspartame: https://www.youtube.com/watch?v=92r1oOul0kM Amino acid summary: https://youtu.be/shM19vvmhWE?si=erXDL-e0oLNeIUVz SDS-PAGE information: • https://www.labxchange.org/library/items/lb:LabXchange:1aba8e2f:video:1 • https://www.labxchange.org/library/items/lb:LabXchange:e2258a52:video:1 •Simu...

Cool animation: https://youtu.be/jlO8NiPbgrk?si=PIC15dKBkbCDtlvS Lab girl: an excellent book about being a female scientist and plants, helped me to appreciate plants much more: https://www.amazon.com/Lab-Girl-Hope-Jahren/dp/1101873728

Quick review of the importance of safety in the microbiology lab Salmonella infection from teaching labs: https://www.cdc.gov/salmonella/typhimurium-07-17/index.html#:~:text=CDC%20and%20public%20health%20officials,were%20reported%20from%2016%20states.

Dr. B explains why she started this podcast and what to expect content wise in the near future.

Commentary on an article by Maryn McKenna in Wired magazine: https://www.wired.com/story/the-battle-against-the-fungal-apocalypse-is-just-beginning/