Legible Bio

Shelby Newsad is an early stage venture investor at Compound . I’ve long admired her thesis work in publicly sharing how biotech could unfold over the next decade. In this conversation, we talk about everything from decentralized clinical trials to incumbent vs startup advantages in biotech. Hope you enjoy! Watch on X , YouTube , or Spotify Chapters 07:21 Platform vs Product 14:25 Creative Destruc...

This was an amazing conversation—I learned a lot and hope you do too. Watch on YouTube here . More on RJ/ anabology here . More on Aion Biosciences here . Also check out skin.food (would personally recommend!) Some resources mentioned: literature.bio - RJ’s website where he recommends reading the works of Sidney Fox and Ray Peat Chapters 00:00 - Background and Bioelectricity 10:19 - Gilbert Ling 2...

Watch on YouTube here Chapters 00:00 Evolution of Biotech: Past and Present 05:29 Understanding Sequencing: Basics and Importance 10:07 The Drug Development Process: Then and Now 17:18 The Shift from Small Molecules to Biologics 22:11 Chance and Unpredictability in Drug Discovery 26:35 Sequencing Technologies: DNA, RNA, and Proteins 44:12 Exciting Innovations in Sequencing 53:53 Synthetic Biology...

Watch on YouTube here Learn more about what Ana’s building here ChaptersChapters00:00 Circus to Genetics05:14 Building a Sequencer13:26 The Future of Sequencing: Decentralization and Accessibility18:31 Challenges in Manufacturing and Scaling21:21 Sequencing in Breweries23:47 Building a Platform Company29:54 Misunderstandings about Sequencing35:09 What Does It Mean Go Fast in Biotech?39:36 The Biot...

Also watch on YouTube 00:36 Journey into Biotech: From Education to Industry 03:23 Investing in Biotech: Early Experiences and Lessons Learned 06:11 Starting a Biotech Company: The Initial Steps 09:14 Developing Technology in Biomanufacturing 11:55 Challenges of Venture Capital in Biotech 14:45 Reflections on Business Strategy and Acquisitions 17:39 Exploring the Mining Industry: Insights and Para...