Dr Daniel J. Guerra
Authentic Biochemistry
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Dr Daniel J. Guerra
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Último episódio
31 de out de 2026
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Episódios
ImmunoEpigeneticsIV. Membrane lipid raft components dynamically mediate Tcell reception, hippocampal pyrimidal neuron endocytosis, and lung cancer cell mesenchymal to endothelial transition.DJGPhD. 05.12.2022 29:28
References Respir Res. 2017 Sep 6;18(1):168 Front Behav Neurosci. 2020; 14: 24 JLR Methods| 2020.Volume 61, ISSUE 11, P1512-1523, November 01
Immunoepigenetics 3. EtOH abuse interrupts membrane lipid raft -mediated TCR signaling by decreasing the TF NFAT nuclear translocation and IL-2 transcription.DJGPhD.04.DEC.22.Authentic Biochemistry. 04.12.2022 29:08
Reference Alcohol Clin Exp Res. 2011 Aug; 35(8): 1435–1444
Immunoepigenetics 2. Treg and ILC differentiation and the evolution of lymphocytic response specificity incl. B cell class switch recombination and somatic hypermutation deamination.DJGPhD.2.12.22 02.12.2022 30:00
References Advances in Immunology. 2011 v.109.Pp125 Biomed J. 2014 Sep-Oct;37(5):269-83 Alcohol Clin Exp Res. 2011 Aug; 35(8): 1435–1444 Cell Reports 10, 2043–2054, March 31, 2015 Front. Immunol., 28 September 2015 | https://doi.org/10.3389/fimmu.2015.00493 Front. Immunol., 07 January 2021 Sec. T Cell Biology https://doi.org/10.3389/fimmu.2020.609891
Membrane Biochemistry 86/Immunoepigentics1. The complex divergent roles of Inhibitor of DNA (Id) binding proteins in terminal differentiation and disease states. DJGPhD.01.12.22.Authentic Biochemistry 02.12.2022 30:01
References Cell Reports Volume 17, Issue 11, 13 December 2016, Pages 2827-2836 Cardiovascular Research, cvac159, https://doi.org/10.1093/cvr/cvac159.Published:27 September 2022 Cancer Med. 2012 Oct; 1(2): 176–186. Nat Immunol. 2011 Nov 6; 12(12): 10 Nat Immunol. 2014 Aug; 15(8): 767–776 Stem Cells. 2007 Feb;25(2):500-10.
Membrane Biochemistry 85. EBV latent membrane protein induction of haemopoietic proliferative disease and Id repressor protein transcriptionally mediated terminal differentiation.DJGPhD.30.11.22. 30.11.2022 29:58
References Stem Cell Reviews and Reports volume 17, pages 1486–1499 (2021) BMC Cancer. 2008 Dec 19;8:379 Curr Top Microbiol Immunol. 2015;391:119-49.
Membrane Biochemistry 84. Isolation of membrane protein using non-ionic detergents exposes the prescence of cellular lipid raft domains. DJGPhD. 29.11.22. Authentic Biochemistry. 30.11.2022 29:56
References Methods Mol Biol. 2021; 2268: 1–20
Membrane Biochemistry 83. Countercurrent distribution theory of membrane lipid raft mediated endomebranous sequence ontology. DJGPhD.26.11.22 26.11.2022 29:59
Referernces Dr. Guerra's deductive reasoning
Membarne Biochemistry 82. Coda in absentia. Redux of the epistemological lens and the membrane lipid raft resurfaces. Dr. Daniel J. Guerra. 23.11.22. Authentic Biochemistry Podcast 23.11.2022 29:52
References Timaeus, Plato Dr Guerra's thoughts and lectures N Engl J Med 2005;353:604-15
Membrane Biochemistry 81. Synopsis. Logical judgment and square of opposition applied to lipids as transcription factors and membrane sequence derivatives respectively. DJGPhD19.11.22.Authentic Bioch 19.11.2022 29:59
References Dr Guerra's unpublished writings
Membrane Biochemisty.Steroidogenic endo-nuclear sphingolipid metabolism involving ganglioiside turnover mediates transcription factor de-repression via DAG kinase.DJGPhD.18.11.22. 19.11.2022 30:00
References Dr Guerra's lipid lectures Front Pharmacol. 2020; 11: 569802 B iomolecules 2022 , 12 (10), 1434; https://doi.org/10.3390/biom12101434
Membrane Biochemistry 79. Sphingolipids and cyclic phosphatidic acid control PPAR isoform-mediated gene transcription over lipid metabolism and inflammation. DJGPhD.16.11.22. Authentic Biochemistry 16.11.2022 29:49
References Circulation Research. 2008;102:283–294 Neurochemical Research volume 45, pages 972–988 (2020) Biochim Biophys Acta. 2008 Sep; 1781(9): 519–524.
Membrane Biochemistry 78. Nuclear sphingolipid metabolism controlling cAMP response element-mediated transcription promoting proinflammation and anti-inflammation temporally and spatially.DJGPhD. 15.11.2022 29:46
References Nature Scientific Reports 2017.volume 7, Article number: 18004 Cells 2022, 11(13). https://doi.org/10.3390/cells11132020 European Journal of Endocrinology 2015. (July). 173(4). Front Pharmacol. 2020; 11: 569802.
Membrane Biochemistry 77. Membrane lipid mediated IGF-I in contextual expression within discrete organ systems controls an inflammatory valence DJGPhD. 9 November 2022 Authentic Biochemistry 10.11.2022 29:40
References Front Aging Neurosci. 2017; 9: 365 J Physiol Biochem. 2017; 73(2): 245–258 Annu Rev Physiol. 2012; 74: 131–151.
Membrane Biochemistry 76. Introduction to SubCellular-Distribution Mechanisms and Function of Nuclear-Localized Lipids. DJGPhD.06Nov22b.Authentic Biochemistry Podcast 06.11.2022 29:57
References Dr Guerra lecture notes Annu Rev Physiol. 2012; 74: 131–151.
Membrane Biochemistry75. Rational judgment as the epistimological prolegomena to research science:isoprenoid lipid biosynthesis guided event ontologies.DJGPhD.6NOV22.Authentic Biochemistry. 06.11.2022 30:00
Dr Guerra's Lecture notes
Membrane Biochemistry 74. ER-Phosphatidylcholine biosynthesis regulates neuritigenesis and the use of logical judgment in research science. DJGPhD. 03Nov22. Authentic Biochemistry 03.11.2022 29:56
References PLoS One. 2019 Jan 10;14(1):e0210207 Nature Communications volume 9, Article number: 1784 (2018)) Cell Death & Disease volume 8, page e2897; 2017 Nat Cell Biol. 2013 Apr;15(4):373-84 Dev Neurobiol. 2010 Jul; 70(8): 589–603 J. Lipid Res. (2022) 63(8) 100213
Membrane Biochemistry 73. Pathogenic membrane associated phosphatidylcholine and sphingomyelin metabolism is linked to skeletal and CNS pathology. DJGPhD.02NOV22. Authentic Biochemistry 02.11.2022 30:00
References J. Lipid Res. (2022) 63(8) 100213 Front. Cell Dev. Biol., 15 October 2019 Bortlein et al. Cell Death & Disease. 2016. volume 7, page e2488 J. Biol. Chem. 1998;273:14550-14559
Membrane Biochemistry72. DHEA and the steroidogenic pathways as biochemical prolegomena to logical judgments. Dr. Daniel J. Guerra.29.10.22b.Authentic Biochemistry 29.10.2022 29:51
References Dr Guerra's lipid biochemistry lectures Int. J. Mol. Sci. 2019, 20, 4660; doi:10.3390/ijms20194660
Membrane Biochemistry 71. Intracellular-endomembranous cholesterol trafficking and estrogen biosynthesis is under epigenetic control. DJGPhD.29.10.22.Authentic Biochemistry. 29.10.2022 29:55
References Dr Guerra's lipid lectures Periodicum Biologorum 2011. 113(1):43-49 Obstet Gynecol Sci 2014. v.57(2)
Membrane Biochemistry 70. Ketogenesis and cholesterologenesis are mediated by mitochondrial bioenergetics and the ER+Peroxisomal metabolism of VLCPUFA's via membrane domain event ontology.DJGPhD 27.10.2022 29:58
References J Biol Chem v.298(7); 2022 Jul PMC9207681 Antioxidants (Basel). 2021 Jun 3;10(6):906. Dr Guerra lipid lectures
Membrane Biochemistry 69. Distilled electrochemical potential mediated Inner mitochondrial membrane redox and the introduction to sterol involvement.DJGPhD.27.10.22. Authentic Biochemistry 27.10.2022 30:00
Dr. Guerra's Basic Biochemistry Lecture notes
Membrane Biochemistry 68. Elevatum Hypostasis. Dr Daniel J. Guerra. 22.10.22b Authentic Biochemistry 22.10.2022 29:58
Necessary and sufficient knowledge eo ipso obtaining the communicated telos.
Membrane Biochemistry 67. VDAC oligimerization inhibition can block mitochondria-mediated apoptosis and NLRP3 inflammasome activation. DJGPhD.22.10.22.Authentic Biochemistry. 22.10.2022 29:59
References Immunity 2022 551370-1385.e8DOI: (10.1016/j.immuni.2022.06.007 J Biol Chem. 2016 Nov 25; 291(48): 24986–25003. J of Visualized Experiments . 2013; (81): 50966
Membrane Biochemistry 66. Staph aureus infection, autoimmune disease, biliary cholangitis, and neurodegeneration involve NLRP3 Inflammasome activation with core bioenergetic involvement. DJGPhD. 21.10.2022 29:57
References Dr Guerra's immunology lecture notes J Vis Exp . 2013; (81): 50966 Front Immunol. 2019; 10: 1309. Infect Immun . 2013 Dec; 81(12): 4478–4489. Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8
Membrane Biochemistry 65. The integration of pro-inflammatory signaling from a plenum of molecular membranous events: The NRLP3 Inflammsome. DJGPhD. 19.10.22. Authentic Biochemistry. 20.10.2022 29:43
References Dr Guerra's Immunology lectures Am J Gastroenterol. 2004 Nov;99(11):2147-9. Front Immunol. 2019 Jun 7;10:1309 Nat Rev Gastroenterol Hepatol. 2019 Dec 9 I mmunity Volume 55 Issue 8 Pages 1370-1385.e8 (August 2022) DOI: 10.1016/j.immuni.2022.06.007
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