VJOncology Podcast

The advent of immune checkpoint inhibitors as a distinct class of immunotherapy has made a large impact within the field of oncology, providing a form of treatment that utilizes the host immune system to target the cancer. Immune checkpoint inhibitors regulate the immune system and prevent autoimmunity, with cytotoxic T lymphocyte-associated molecule-4 (CTLA-4), programmed cell death receptor-1 (P...

The International Workshop on CAR-T (iwCAR-T) 2022 featured many updates on the development of CAR-T therapies for the treatment of solid tumors. In this podcast, we hear from Jose Conejo-Garcia of Moffitt Cancer Center, Tampa, FL, and Jennifer Specht of Fred Hutchinson Cancer Research Center and the University of Washington, in Seattle, WA, as they discuss the latest CAR-T updates in breast cance...

Circulating tumor DNA (ctDNA) are small fragments of nucleic acid that are released into the circulating system via multiple mechanisms including apoptosis and necrosis, thereby reflecting the genomic landscape of the tumor from which it was derived. Due to its short half-life, ctDNA can facilitate in tracking the tumor burden in real-time, offering a valuable minimally invasive opportunity to mon...

The International Workshop on CAR-T (iwCAR-T) 2022 featured many updates on the development of CAR T-cell therapies for the treatment of solid tumors. This roundtable discussion on the development of cellular therapies in lung cancer was chaired by Melissa Johnson, MD from the Sarah Canon Research Institute and Tennessee Oncology, Nashville, TN, and featured Sandip Patel, MD,UC San Diego Health, S...

The American Society of Clinical Oncology Annual Meeting 2022 brought together thousands of experts in oncology to hear new data and discuss how to improve the diagnosis and treatment of patients with cancer. In this podcast, we hear from some of the leading experts in gastrointestinal cancer, as they discuss the biggest trials and hot topics from the meeting. For pancreatic cancer, we heard from...

The American Society of Clinical Oncology Annual Meeting 2022 brought together thousands of experts in oncology to hear new data and discuss how to improve the diagnosis and treatment of patients with cancer.   In this podcast, we hear from some of the leading experts in genitourinary cancer, as they discuss the biggest trials and hot topics from the meeting. For prostate cancer, we hear from Prof...

The American Society of Clinical Oncology Annual Meeting 2022 brought together thousands of experts in oncology to hear new data and discuss how to improve the diagnosis and treatment of patients with cancer.   In this podcast, we hear from some of the leading experts in breast cancer, as they discuss the biggest trials and hot topics from the meeting. Dr Kevin Kalinsky gives an overview of the MA...

The American Society of Clinical Oncology Annual Meeting 2022 brought together thousands of experts in oncology to hear new data and discuss how to improve the diagnosis and treatment of patients with cancer. In this podcast, we hear from some of the leading experts in lung cancer, as they discuss the biggest trials and hot topics from the meeting. Dr Narjust Duma discusses the key challenges face...

This year’s International Workshop on CAR-T (iwCAR-T) featured a whole day on the development of CAR T-cell therapies in solid tumors. CAR T-cell therapy has revolutionized the treatment of patients with hematological malignancies however, application in solid tumors has historically seen limited success.  In this discussion, Julian Molina, MD from the Mayo Clinic, Rochester, MN, Daniel Abate-Daga...

Catch up on our highlights from Day 3 of ASCO 2022!

Catch up on our highlights from Day 2 of ASCO 2022!

Catch up on our highlights from Day 1 of ASCO 2022!

This year’s European Society for Radiotherapy and Oncology (ESTRO) annual congress took place in Copenhagen, Denmark, from 6-10 May 2022, and brought together leading experts from across the field of radiation oncology. In this podcast, we focus on some of the significant trial updates presented at the congress. We shall hear from Francesco Cortiula, MD, University Hospital of Udine, Udine, Italy,...

The development of complex and effective therapies has improved outcomes in breast cancer, highlighting the need for strategies to escalate and de-escalate treatment. In this exclusive VJSession, Roberto Salgado, MD (GZA Ziekenhuizen Campus Sint-Augustinus, Wilrijk, Belgium) and Marleen Kok, MD (Netherlands Cancer Institute, Amsterdam, Netherlands) discuss the latest advances in triple-negative br...

The European Society for Clinical Oncology (ESMO) Breast Cancer Conference was a hybrid event, held virtually and Berlin, Germany. This renowned meeting brought together global experts who disseminated the latest thinking in breast cancer. VJOncology had the opportunity to speak to Rupert Bartsch, Medical University Vienna, Vienna, Austria, Paolo Tarantino, Dana Farber Cancer Institute, Boston, MA...

This year’s American Association for Cancer Research (AACR) congress took place in New Orleans, LA, from 8-13 April 2022, and brought together leading experts from across the field of oncology. There were trial updates and presentations of real-world data, as well as discussions on the best ways to improve care for patients. In this podcast, we focus in on gastrointestinal cancers and hear from Mi...

Improvements in early detection, diagnosis, and management have decreased cancer-related mortality, however, challenges associated with personalized care remain. Artificial intelligence (AI) combines computer science and robust datasets to enable problem-solving and has applications within the field of oncology.  In this podcast, we hear from Ángel Alberich-Bayarri, PhD, QUIBIM – Quantitative Imag...

In a world that is still acclimatizing to the COVID-19 pandemic, the fragility of many aspects of our society has been laid bare. Global health care systems were among the most seriously affected by the SARS-CoV-2 which has put a spotlight on the integral role of nurses not only in day-to-day patient care and running of healthcare facilities but also in public education and awareness campaigns, pu...

In this podcast, we hear from genitourinary (GU) cancer experts Tian Zhang, MD, Duke Cancer Center, Durham, NC, and Scott Tagawa, MD, MS, FACP, Weill Cornell Medicine, New York City, NY, as they discuss some of their highlights in prostate and kidney cancer research presented at the 2022 ASCO GU Cancers Symposium, held in San Francisco, CA. Listen to learn about the latest clinical research and pr...

Lung cancer is one of the most common cancers in the world, and has a very low survival rate, partly due to many patients being diagnosed only once their disease has reached an advanced stage. Screening programmes for high-risk populations are a possible solution to this problem, as it would help to identify more lung cancer cases when they are in early stages, and are therefore more treatable. In...

Resistance to endocrine therapy in patients with hormone-receptor-positive (HR+), HER2-negative breast cancer inevitably results in relapse and metastasis, leading to death. Understanding mechanisms of intrinsic and acquired resistance have been the focus of many clinical studies. Recent advances including the use of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors and phosphoinositide 3-kinase (PI...

Clinical trials presented at the the American Society of Clinical Oncology (ASCO) Genitourinary Cancers (GU) Symposium 2022 have been investigating treatment options for patients with advanced or metastatic UC who are ineligible for or have progressed on platinum-based chemotherapy, in hopes of improving patient prognosis. The LEAP-011 trial explored the addition of the VEGFR inhibitor, lenvatinib...

The San Antonio Breast Cancer Symposium (SABCS) 2021 saw ground-breaking data and developments in breast cancer being presented and in this special podcast, leading breast cancer experts Hope Rugo (UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA) and Dave Cescon (Princess Margaret Cancer Center, Toronto, Canada), dissect the latest advances in the field and offer their uniq...

In this episode of the VJOncology podcast, a panel of leading gastrointestinal (GI) cancer experts offer their perspectives on the key GI cancer data presented at the 2022 ASCO GI Cancers Symposium, held in San Francisco, CA, in January 2022. In this podcast, Nataliya Uboha, MD, PhD, University of Wisconsin, Madison, WI, is joined by Ghassan Abou-Alfa, MD, MBA, Memorial Sloan Kettering Cancer Cent...

The ASCO Genitourinary (GU) Cancers Symposium took place on the 17-19th February 2022, in San Francisco, CA. Leading experts gave updates on trials in prostate cancer, urothelial carcinoma, renal cell carcinoma, and rare GU cancers, as well as discussing hot topics in the field. In this podcast, we hear from several experts in the field of prostate cancer, as they update us on some of the biggest...