Unseen Upside: Investments Beyond Their Returns

What does it take to build something that lasts for generations? In this special crossover episode from Cambridge Conversations , we explore how bold vision, patient capital, and a deep commitment to community helped transform San Antonio’s Pearl district from a shuttered brewery into a thriving destination. Host Willis Wilson hands the mic to Unseen Upside host Hillary Ribaudo, who travels to San...

Step into a conversation about the power of investing in women—and the ripple effects that follow. This International Women’s Day, discover how closing the gender gap in leadership and capital unlocks new opportunities, fuels economic growth, and strengthens communities. This discussion goes beyond the numbers; it highlights the stories, challenges, and progress that emerge from supporting women a...

Step into the world of advanced robotics, where AI is transforming how we work, move, and live.  Discover how surgical robots, autonomous vehicles, and AI-driven exoskeletons are advancing healthcare, streamlining operations, and restoring independence for individuals. Hear from innovators at Xeno Dynamics, leading investors, and a family whose journey with multiple sclerosis (MS) inspired a found...

Travel to a Vermont dairy farm to see how AI is reshaping agriculture. Learn how data-driven tools are making farming more sustainable and productive, and how companies like Inari Seeds are engineering crops for a changing climate. This episode uncovers the future of food—where technology, tradition, and environmental stewardship meet. Guests include: Lucas Mann , Co-Founder and Managing Partner o...

Venture into the world of AI-driven drug discovery, where new models are making the process faster, safer, and more ethical. Discover how Axiom’s pioneering technology is helping to eliminate the need for animal model testing, paving the way for more humane and effective drug development. Hear from leaders at Cleveland Clinic and Amplify about how AI is transforming healthcare for patients and pro...

What happens when AI meets the earth’s natural heat? Join us as we explore how Fervo and global partners are harnessing AI to unlock geothermal energy’s potential—delivering clean, flexible power around the clock. From Houston to the Middle East, we examine the science, policy, and investment trends driving the energy transition, and how geothermal could help power the AI revolution itself. Guests...

Discover how AI is breaking down barriers to education and tailoring learning experiences for students everywhere. From Duolingo’s global reach to the innovative use of AI in real classrooms at Miss Porter’s School in Connecticut, this episode explores how technology is expanding access, enhancing engagement, and equipping the next generation with essential skills—while ensuring integrity and safe...

Get ready—Season 6 of Unseen Upside launches October 21. This season, we’re taking you behind the scenes to explore how AI is transforming our world. From labs and classrooms to clinics and fields, we’ll follow the capital and uncover how AI is driving the next chapter of human progress. Tune in for episode one on your favorite podcast platform, Tuesday, October 21.

Once numbering in the tens of millions, the American bison was nearly driven to extinction by the early 1900s. But a coalition of conservationists, Native American communities, and private partners were determined to save the species. Join us for this mini episode of Unseen Upside: Investments Beyond Their Returns , as we share the remarkable story of the bison’s restoration alongside John Calvell...

Summer isn't over just yet-- Unseen Upside is bringing you Part 2 of our summer reading list! Tune in as we share more book recommendations from investors and entrepreneurs on the leading edge of healthcare. Check the show notes for links to all the recommendations, and catch up on past episodes in our podcast feed. Stay tuned for Season 6—launching soon. Featured Recommendations: The Frozen River...

As summer heats up, Unseen Upside brings you a special two-part mini-episode packed with inspiration for your reading and listening list. From thought-provoking explorations of social justice and capitalism to the latest in women’s sports and business innovation, this short episode is your guide to what’s fueling the minds and spirits of those driving change in healthcare, housing, and beyond. Whe...

There’s a maternal health crisis in the United States, with high rates of maternal mortality, especially among marginalized communities. But what is being done to improve it?  Through conversations with those on the front lines, we uncover the stark health inequities that exist in maternal healthcare and the developments created to tackle them. We also hear from mothers who have firsthand experien...

How will evolving digital technologies impact healthcare delivery, patient experience, and access to care? According to new venture-backed companies, they can advance health equity, democratize access, and empower individuals to take control of their health journey. Alongside industry pioneers and investors, we explore digital health advancements such as telemedicine, remote monitoring, and data-d...

Join us in Kotzebue, Alaska to explore the issue of rural healthcare and the inequities faced by these communities. We shine a light on innovative solutions aimed at improving rural healthcare delivery, like a program called Siamit that’s connecting cutting-edge medicine from Massachusetts General Hospital (MGH) and Harvard Medical School to the tribal regions of Alaska. We also look at the role o...

Prescription drug prices in the United States are 2.78 times higher than in other developed countries, but why? We untangle the barriers surrounding drug affordability and find out why accessing life-saving medications is costly to so many. Joined by experts, advocates, and one Cystic Fibrosis patient relying on expensive medication to live, we examine the complex factors contributing to the high...

Join us as we head to the Bronx to examine the critical intersection of housing and health and the innovative solutions that are aiming to address the affordable housing crisis in major cities like New York and LA. Through conversations with non-profit leaders and impact investors, we dive into how affordable housing impacts public health and health equity, highlighting the investment strategies a...

How does venture capital contribute to advancing health equity and public health? Find out on season five of Unseen Upside , premiering Tuesday, October 8. This season, we dive into how today's investment decisions are shaping tomorrow's innovations in critical areas such as affordable housing, maternal health, drug pricing, and more. Join us for engaging conversations with investors and entrepren...

While we’re busy pulling together stories for the fifth season of Unseen Upside , we thought you might be curious about what it is that Cambridge Associates actually does. In a nutshell, we have the privilege of partnering with some of the world’s top institutional investors—like nonprofits, universities, hospitals, pension plans, and even private families—and we try to help them reach their inves...

Artificial intelligence is transforming healthcare, unleashing new investment opportunities. From cancer screening to drug discovery, AI promises to augment clinical decision-making and improve care.  We’ll explore the surging ecosystem of medical AI innovations, from the emerging tech landscape to practical deployment. But what are the challenges facing real-world implementation? Which applicatio...

Autoimmune diseases like lupus impact over 5 million patients globally, but treatment options remain limited. Now, decoding the once mysterious "dark genome" could bring new therapies. Over 90% of our DNA was once considered "junk"—but we’ve learned this dark matter regulates gene expression and human disease. This episode takes you to the pioneers who are unlocking the dark genome's potential to...

Obesity is a global health crisis, with over 650 million adults affected worldwide. This drives massive economic and disease burdens. Yet new treatment options like GLP-1 drugs offer hope. This episode analyzes the investment landscape and future of obesity therapeutics, focusing on transformational GLP-1 drugs like Ozempic that curb appetite. Join us as we investigate the promise and challenges o...

Precision oncology represents an exciting shift in cancer treatment from a one-size-fits-all approach to personalized care based on each patient's unique cancer and molecular makeup. In this episode, we'll explore how precision oncology is transforming the landscape of cancer care and improving outcomes at leading hospitals like St. Jude Children’s Research Hospital. We'll discuss the latest preci...

Thanks to medical advances, we're living longer lives but with that comes rising rates of Alzheimer's disease. Currently 6 million Americans have Alzheimer's, and that could triple by 2050. This episode explores emerging innovations offering hope against neurodegenerative diseases. We'll discuss promising new drugs that could slow cognitive decline and the strides scientists are making towards und...

The mental health crisis is growing, especially among Gen Z (91% report anxiety or depression). This episode explores innovations in mental healthcare access, new therapeutic approaches for young people and families, and how hospitals are striking creative partnerships to tackle this emergency. Tune in to learn what’s working and showing promise in mental healthcare, glimpses of what the future co...

The future of healthcare is here. Get an an inside look at the innovations transforming lives on season four of Unseen Upside , premiering Tuesday, February 6. This season, we pull back the curtain on cutting-edge advancements at the intersection of technology and medicine, learn how AI is revolutionizing diagnostics and treatment, discover the potential of GLP-1s to combat obesity, and how breakt...