This Week in Virology

Hosts:  Vincent Racaniello , Dickson Despommier ,  Alan Dove , and  Rich Condit The latest Zika virus news from the ConTWiVstadors, including a case of female to male transmission, risk of infection at the 2016 summer Olympics, a DNA vaccine, antibody-dependent enhancement by dengue antibodies, and sites of replication in the placenta. Links for this episode Zika virus disease in the US (CDC) Fema...

Host:  Vincent Racaniello Guest:  Sandy Weller Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation and cleavage and packaging of viral DNA genomes.   Become a  patron  of TWiV! Links for this episode Cell killing by  avian leukosis virus  (Sandy's first paper, J Virol) ND10 protein  and herpes simplex virus replication (J Virol) Recombination  ...

Host:  Vincent Racaniello Guest:  David Tuller Vincent speaks with David Tuller about flaws in the U.K's $8 million PACE trial for chronic fatigue syndrome, and efforts to have the trial data released.   Become a  patron  of TWiV! Links for this episode Science and journalism ( TWiV 111 ) Chronic fatigue syndrome and the CDC (virology blog) PACE trial (Lancet) Trial by error part one , two , three...

Host:  Vincent Racaniello Guest: Peter Palese Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines.   Become a  patron  of TWiV! Links for this episode Palese Laboratory Pig kidney neuraminidase (Hoppe Seylers Z Physiol Chem) DNAse in cytoplasmic DNA virus (Virology) Inhibitor of influenza virus neuramini...

Hosts:  Vincent Racaniello,   Rich Condit , and Kathy Spindler Guest:  Stephen J. Russell From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy - using viruses to treat cancers.   Become a  patron  of TWiV! Links for this episode Hokies go viral ( TWiV 285 ) MV NIS de Myelo ( TWiV 298 ) Remission of disseminated my...

Hosts:  Vincent Racaniello  and  Alan Dove Guest:  Erica Ollmann Saphire Vincent and Alan speak with Erica about her career and her work on understanding the functions of proteins of Ebolaviruses, Marburg virus, and other hemorrhagic fever viruses, at ASM Microbe 2016 in Boston, MA.   Become a  patron  of TWiV! Links for this episode Structure of antibodies  bound to Ebola virus glycoprotein  (PNA...

Hosts:  Vincent Racaniello , Alan Dove , Rich Condit , and Kathy Spindler The TWiVerati revisit possible sexual transmission of Zika virus, and reveal how a cell protein that allows hepatitis C virus replication in cell culture enhances vitamin E mediated protection against lipid peroxidation.   Become a patron of TWiV! Links for this episode Late sexual transmission of Zika virus (Lancet) Zika vi...

Host:  Vincent Racaniello Guests:  Michael Diamond , Michaela Gack , Laura Kramer , and Charles Rice Four virologists discuss our current understanding of Zika virus biology, pathogenesis, transmission, and prevention, in this special live episode recorded at the American Society for Microbiology in Washington, DC. [powerpress url="http://traffic.libsyn.com/twiv/TWiV392.mp3"] Click arrow to play D...

Hosts:  Vincent Racaniello ,  Alan Dove , and  Rich Condit Guests:  David Pride  and  Forest Rohwer If you have always wanted to know what coral reefs and the human oral cavity have in common, listen as guests David Pride and Forest Rohwer talk about their work on the microbiomes and viromes of these two environments, and you'll also understand why mucus is cool.   Links for this episode Lytic to...

Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , and Kathy Spindler Guests: Ethan Jackson and Jonathan Carlson Project Premonition, a Microsoft Research project that uses drones to capture mosquitoes and analyze them for pathogens, preprint servers, and three mouse models for Zika virus induced birth defects are the topics of this episode hosted by the TWiumvirate and th...

Host:  Vincent Racaniello Guest: Stan Lemon Vincent speaks with Stan Lemon about his career in virology, from early work on Epstein Barr virus, through making essential discoveries about hepatitis A virus, hepatitis C virus, and rhinoviruses. Links for this episode Live in Edmonton, Eh? ( TWiV 235 ) Replication of EBV in epithelial cells (Nature) Returning to Carolina after 14 years Evolutionary o...

Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , and Kathy Spindler Preprint servers, the structure of an antibody bound to Zika virus, blocking Zika virus replication in mosquitoes with Wolbachia , and killing carp in Australia with a herpesvirus are topics of this episode hosted by Vincent, Dickson, Alan, and Kathy. Links for this episode biorXiv preprint server Please review Vaccin...

Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , and Kathy Spindler Guest:  Nina Martin Nina Martin joins the TWiV team to talk about the movie Vaxxed, her bout with dengue fever, and the latest research on Zika virus.   Links for this episode Public Health United Fifty Shades of Science (TEDx) Parents convicted in death of toddler (Science Based Medicine) CDC: Zika virus causes micro...

Hosts:  Vincent Racaniello ,  Rich Condit , and  Kathy Spindler Guests:  Ted Diehl  and  Welkin Johnson Ted and Welkin inform the TWiV team how the evolution of ancient retroviruses can be inferred by studying their sequences in the genomes of modern mammals, and join in a discussion of virus dispersal during different methods for drying hands.   Links for this episode More fun than a monkey full...

Hosts:  Vincent Racaniello  and  Dickson Despommier Guest:  Stuart Firestein Stuart joins Vincent and Dickson to talk about his sequel to  Ignorance , a book called  Failure , which seeks to make science more appealing by revealing its faults.   Links for this episode Stuart Firestein's site Ignorance  with Stuart Firestein (TWiV Special) The pursuit of  ignorance  (TED) Ignorance  by Stuart Fires...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove  and  Rich Condit Guests:  Nischay Mishra and Ian Lipkin Nischay and Ian join the TWiVions to discuss mass die-offs of tilapia by a novel orthomyxo-like virus, Ian's editorial on the movie Vaxxed , and new vaccines to prevent dengue virus infections, including a human challenge model.    Links for this episode Novel orthomyxo-like virus...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove  and  Kathy Spindler Guest:  Esper Kallas Esper and the Merry TWiXters analyze the latest data on Zika virus and microcephaly in Brazil, and discuss publications on a mouse model for disease, infection of a fetus, mosquito vector competence, and the cryo-EM structure of the virus particle.   Links for this episode Zika virus in the Amer...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove  and  Kathy Spindler Guests: Nels Elde and Edward Chuong Nels and Ed join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses.   Links for this episode Endogenous retroviruses and regulation of...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove , Rich Condit , and  Kathy Spindler Guest: Carl Zimmer Carl Zimmer joins the TWiV team to talk about his career in science writing, the real meaning of copy-paste, science publishing, the value of Twitter, preprint servers, his thoughts on science outreach, and much more. Links for this episode Carlzimmer.com All Carl's articles at NYTi...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove , Rich Condit , and  Kathy Spindler The TWiVeroos deliver the weekly Zika Report, then talk about a cryoEM structure of a plant virus that reveals how the RNA genome is packaged in the capsid, and MIMIVIRE, a CRISPR-like defense system in giant eukaryotic viruses.   Links for this episode First worms, then viruses, now dormant cyber pat...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove ,  Rich Condit , and  Kathy Spindler Guest:  Scott Tibbetts Scott Tibbetts joins the TWiVists to describe his work on the role of a herpesviral nocoding RNA in establishment of peripheral latency, and then we visit two last minute additions to the Zika virus literature. Links for this episode Noncoding RNA required for  establishment of...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove , and  Kathy Spindler Guests: Greg Smith and Mark Fuccio Greg Smith joins the TWiVirate to reveal how his lab discovered a switch that controls herpesvirus neuroinvasion, and then we visit the week's news about Zika virus.   Links for this episode Dynamic ubiquitination drives herpesvirus neuroinvasion (PNAS) Releasing Zika virus data i...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove ,  Rich Condit , and  Kathy Spindler The TWiVniks review the past week's findings on Zika virus and microcephaly, and reveal a chicken protein that provides insight on the restriction of transmission of avian influenza viruses to humans.   Links for this episode Larvicide  not involved in microcephaly (CBS News) Obama seeks  $1.8b for Z...

Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove ,  Rich Condit , and  Kathy Spindler Guest:  Jeremy Luban The TWiV team discusses the latest data on Zika virus, including ocular defects in infants with microcephaly, and isolation of the entire viral genome from fetal brain tissue.   Links for this episode Ocular findings in infants with microcephaly ( JAMA  and  Arq Bras Oft ) Eviden...

Hosts:  Vincent Racaniello ,  Alan Dove ,  Rich Condit , and  Kathy Spindler Guests: Carolyn Coyne ,  Helen Lazear , and  Jeremy Luban The TWiVziks present everything you want to know about Zika virus, including association of infection with microcephaly and Guillain-Barré syndrome, transmission, epidemiology, and much more.   Links for this episode Zika outbreak in  Brazil  (EID) 13:40 Zika  summ...