This Week in Virology

In his weekly clinical update Dr. Griffin discusses co-detections of other respiratory viruses among children hospitalized with COVID-19, preprint review should form part of PhD programs and postdoc training, early and increased Influenza activity among children, COVID-19 vaccines versus pediatric hospitalization, SARS-CoV-2 variant-related abnormalities detected by prenatal MRI, protective effect...

TWiV covers a study of SARS-CoV-2 persistence at multiple sites in the human body, and the role of endogenous retroviruses in ageing and senescence. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove ,  Brianne Barker , and  Angela Mingarelli Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode •Research assistant positio...

In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for sever...

Daniela joins TWiV to discuss her career and her research on T cells, their role in infection with SARS-CoV-2, T cell epitopes and why a variant that evades T cell immunity is not likely to emerge. Hosts:  Vincent Racaniello , Alan Dove , and Brianne Barker Guest: Daniela Weiskopf Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode...

In his weekly clinical update Dr. Griffin discusses poliovirus returns to New York wastewater, COVID-19 is more widespread in animals than we thought, increasing ventilation reduces SARS-CoV-2 airborne transmission in schools, the use of carbon dioxide monitoring to assess ventilation at a national infectious diseases conference, effectiveness of the bivalent mRNA vaccine in preventing severe COVI...

Felicia joins TWiV to discuss her career and her research on human cytomegalovirus, which infects most of us for our entire lives yet mainly causes disease in the immunosuppressed. Hosts:  Vincent Racaniello ,  Alan Dove , and  Brianne Barker Guest:  Felicia Goodrum Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode •Research assi...

In his weekly clinical update Dr. Griffin discusses the infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave, virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants, antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, comparative effectiveness of third doses of mRNA-based COVID-19...

In the first epitope of 2023, TWiV reviews our coverage of virology in 2022, including favorite story arcs, episodes, show titles, and much more. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Rich Condit ,  Kathy Spindler , and  Brianne Barker Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Our favorite 2022 virology stor...

In his weekly clinical update Dr. Griffin discusses modelling the adjustment of COVID-19 response and exit from dynamic zero-COVID in China, canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event, two masks can be worse than one: N95 respirator failure caused by an overlying face mask, airflow patterns in double-occupancy patient rooms may contribute to roomma...

Carl Zimmer visits the Incubator to record a wide-ranging conversation about COVID-19, including origins, vaccines, public health responses, and impact on society. Host:  Vincent Racaniello Guest:  Carl Zimmer Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Intro music is by  Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

TWiV reviews eukaryotic viruses recovered from ancient permafrost, a mistake made by scientists on Omicron origins, and close relatives of MERS-CoV from bats that bind ACE2 for entry into cells. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Alan Dove ,  Rich Condit , and  Brianne Barker Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for...

In his weekly clinical update Dr. Griffin discusses how immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection, prevalence of SARS-CoV-2 and influenza coinfection and clinical characteristics among children and adolescents aged

Vincent travels to the NIH campus to speak with Jeffery Taubenberger about his career, the 1918 influenza pandemic, deciphering the genome sequence of the virus from tissues of disease victims and using it to rescue infectious virus. Host:  Vincent Racaniello Guest:  Jeffery Taubenberger Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this...

Brazilian infectious diseases physician Esper Kallas returns to TWiV to discuss the state of viral diseases in his country, including those cause by Zika, dengue, and yellow fever viruses, MPOX, and SARS-CoV-2. Hosts:  Vincent Racaniello  and  Alan Dove Guest:  Esper Kallas Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Suppor...

In his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down t...

Vincent travels to Cornell University to speak with Gary Whittaker about regulation by proteolytic processing of the fusion activity of the spike protein of SARS-CoV-2, and feline coronavirus transmission, replication and disease. Hosts:  Vincent Racaniello Guest: Gary Whittaker Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode S...

Paul Offit returns to TWiV to discuss why the bivalent booster dosing story should be a cautionary tale of how not to move forward in this pandemic. Hosts:  Vincent Racaniello and Rich Condit Guest: Paul Offit Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Antibody responses to bivalent booster (bioRxiv) Immunogenicity of biva...

Astrophysicist Chiara Mingarelli joins TWiV to discuss her career and her work using pulse timing arrays to study the gravitational wave background, ripples in the fabric of spacetime that are caused by events such as the merging of black holes. Hosts:  Vincent Racaniello , Rich Condit , Kathy Spindler , and Angela Mingarelli Guest: Chirara Mingarelli Subscribe (free):  Apple Podcasts ,  Google Po...

In his weekly clinical update Dr. Griffin discusses Mpox (formerly monkeypox) in women: epidemiological features and clinical characteristics of mpox cases in Spain, April to November 2022, triage of patients with Ebola virus disease, SARS-CoV-2 serology and self-reported infection among adults, serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal...

Dan Wilson of Debunk the Funk joins TWiV to explain why he decided to take on science misinformation and how he critiques people who promulgate incorrect information. Hosts:  Vincent Racaniello , Dickson Despommier , Rich Condit , and Brianne Barker Guest: Dan Wilson Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support Micro...

In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell me...

The TWiV team reveals a variant SARS-CoV-2 that emerged in deer with deer-to-human transmission, and hybrid virus particles produced by co-infection with influenza virus and respiratory syncytial virus particles. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of ...

In his weekly clinical update Dr. Griffin discusses human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks, changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States, updates on COVID-19–related mortality, impact of community masking on COVID-19, effectiveness of the COVID-19 vaccines against hos...

Cedric and John join TWiV to discuss their research showing that a human protein derived from an ancient retrovirus infection can protect against infection by other retroviruses. Hosts:  Vincent Racaniello , Rich Condit , and Kathy Spindler Guest: Cedric Feschotte and John Anthony Frank Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this e...

In his weekly clinical update Dr. Griffin discusses the four things to know about RSV, the burden of respiratory syncytial virus in healthy term-born infants in Europe, the diagnostic accuracy of rapid diagnostic tests for Ebola virus disease, evaluating the accuracy of self-collected swabs for the diagnosis of monkeypox, tecovirimat is effective against human monkeypox virus in vitro at nanomolar...