This Week in Pediatric Oncology

In this episode Dr. Timothy Cripe and Dr. Brenda Weigel are joined by FDA's Dr. Nicole Drezner, pediatric oncologist and the Deputy Division Director of the Division of Oncology 2 who led the FDA review and publication on the approval of DFMO. Listen in on the discussion surrounding the historic approval of DFMO, the first ever oncology drug approved in the setting to prevent relapse using an exte...

Dr. Luca Szalontay,  Assistant Professor of Pediatrics at Columbia University Medical Center, discusses the work of Columbia's Initiative for Drug Delivery Innovation which is exploring new treatments for pediatric brain tumors utilizing Convection Enhanced Delivery and Focused Ultrasound. This initiative has launched a new clinical trial using Focused Ultrasound for patients with  progressive dif...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/ACFprGG10M0 In this episode, our host, Dr. Timothy Cripe from Nationwide Children’s Hospital, is joined by Dr. Seth Rotz - pediatric hematologist/oncologist and the Director of the Fertility Preservation Program at the Cleveland Clinic in Cleveland, Ohio. Listen in as they discuss Dr. Rotz’s career & specialty in fertility preservation for cancer pati...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/jj3wJU0G7GI Listen in as our hosts, Dr. Tim Cripe & Dr. Brenda Weigel, are joined by Al Gustafson, from The Swifty Foundation, and Dr. Angela Waanders, from Lurie Children's Hospital of Chicago, to discuss the "Gift from a Child" program. This program is led by The Swifty Foundation & helps advocate and educate about post mortem pediatric brain tissue...

Listen in & join the TWiPO team in this special live recorded episode. Our host, Dr. Tim Cripe, along with his Nationwide Children’s Hospital colleagues, Dr. Ryan Roberts, Dr. Elaine Mardis & Dr. Katherine Miller, are joined by Dr. Trevor Pugh, who is a clinical laboratory geneticist from the University of Toronto in Canada. Tune in as they all discuss Dr. Pugh’s specialty in genomics & his recent...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/yyQ08ny_hDU Join our host, Dr. Timothy Cripe from Nationwide Children's Hospital, as he’s joined with Dr. Jim Geller from Cincinnati Children’s Hospital to discuss his expertise in pediatric liver cancer - hepatoblastoma. In this episode, we are also specially joined by Kelly & Jessica Woolwine as they tell their story of how they navigated the hepato...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/Z1D-7i4oy1s   Our host, Dr. Timothy Cripe from Nationwide Children's Hospital, is joined by Dr. Martin McCabe from the University of Manchester to discuss the results of the rEECur trial. The rEECur trial is an international randomized trial conducted on recurrent and primary refractory Ewing sarcoma patients. Dr. McCabe leads a discussion on the gene...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/oR0KN5VFDVc Tune in as our host, Dr. Brenda Weigel from the University of Minnesota, is joined by Dr. Garrett Brodeur to discuss his expertise in genetic predispositions in childhood cancer. Dr. Brodeur is the Director of the Pediatric Cancer Predisposition Program at the Children’s Hospital of Philadelphia (CHOP) - and listen in as he discusses his j...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/SvTprrL8wnY This Week in Pediatric Oncology #105 - January 3, 2023 Happy New Year from the TWiPO team! We are opening up this new year with an episode on building a pediatric cancer disease community. Our host, Dr. Timothy Cripe from Nationwide Children's Hospital, with special co-host, Donna Ludwinski from Solving Kids' Cancer, is joined by Ann Graha...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/41kwZNhrBBc This Week in Pediatric Oncology #104 - December 13, 2022 In this episode, Dr. Timothy Cripe & Dr. Brenda Weigel, are joined by Dr. Joshua Schiffman - CEO & Co-Founder of PEEL Therapeutics, Inc. Dr. Schiffman’s own personal childhood cancer journey paved his way into the pediatric cancer field. Listen in as he discusses the formation of PEE...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/SkyYLIZxQWA This Week in Pediatric Oncology #103 - November 30, 2022 Join us as our hosts, Dr. Timothy Cripe & Dr. Brenda Weigel, are joined by Dr. Roger Packer from Children’s National Hospital in Washington DC. Dr. Packer is the Senior Vice President of the Center for Neurosciences and Behavioral Medicine at Children’s National, which is introducing...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/inNQc6x9Jy8 This Week in Pediatric Oncology #102 - November 10, 2022 Tune in as our hosts, Dr. Timothy Cripe & Dr. Brenda Weigel, are joined again by Dr. Douglas Hawkins - who is the current Chair of the Children’s Oncology Group (COG). They discuss in depth the findings of a presented published paper regarding the inequities of childhood cancer outco...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/qVMiwnfVQZY Tune in as our hosts, Dr. Tim Cripe & Dr. Brenda Weigel, are joined by Dr. Will Parsons who is the Co-Director of the Brain Tumor Program at Texas Children's Hospital in Houston, TX. In this episode, Dr. Parsons discusses the background & purpose behind the NCI Pediatric MATCH Trial, the current status of the trial itself, and how the data...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/8Lj3uFHWo60 Happy 100th Episode to the This Week in Pediatric Oncology Podcast! In this special milestone episode, our hosts, Dr. Timothy Cripe & Dr. Brenda Weigel, are joined by Scott Kennedy & Donna Ludwinski from Solving Kids' Cancer to reminisce on the history & creation of TWiPO and talk about their favorite podcast episodes from over the years....

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/bDbtses4w2E Tune in as our hosts, Dr. Timothy Cripe & Dr. Brenda Weigel, are joined by Dr. Samuel Volchenboum who is an Associate Professor of Pediatrics from the University of Chicago. Dr. Volchenboum spearheaded an international effort through two data platforms called the Pediatric Cancer Data Commons (PCDC) & GEARBOx (Genomic Eligibility Algorithm...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/FBgbCA6TZK4 Listen in as our host, Dr. Timothy Cripe, is joined by Dr. Jonathan Finlay to discuss his acclaimed & reputable career within the pediatric cancer landscape. Dr. Finlay reflects on his distinguished journey including how he got into pediatric immunology, how the field has evolved throughout his medical career, his views on exciting technol...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/5TYFsjh91Tw Listen in as our host, Dr. Brenda Weigel from the University of Minnesota, is joined by Dr. Robbie Majzner - an Assistant Professor of Pediatrics in the Division of Hematology and Oncology at Stanford University's School of Medicine. Dr. Majzner goes into great detail about his recent clinical trial on GD2-CAR T cell therapy for H3K27M-mut...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/CEvlSC8dHeQ Listen in as our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined by Dr. Kristopher Bosse: an attending physician in the Division of Oncology at Children's Hospital of Philadelphia (CHOP). Dr. Bosse discusses his latest project that focuses on GPC2 Directed Immunotherapy, including what makes it a better target, the benefits & ch...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/rFd4Fwa_XVg Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined Solving Kids’ Cancer’s patient advocates, Nick Bird & Donna Ludwinski. Nick & Donna, along with other patient advocates, recently published a groundbreaking report, “When Innovation and Commercialization Collide: A Patient Advocate View in Neuroblastoma“. Listen in as they discuss...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/Uf9UOGW3y-Q In this episode, our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined by Dr. Wayne Furman. Dr. Furman recently retired from the Department of Oncology at St. Jude Children’s Research Hospital in Memphis, TN. Prior to his retirement, Dr. Furman had a paper published in the Journal of Clinical Oncology on his Phase II trial using h...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/AFmMxBeZOa4 Tune in as our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, meet with Dr. Rimas Orentas - the Scientific Director of Caring Cross & a Professor from Seattle Children's Hospital. In this episode, Dr. Orentas discusses his expertise in cellular gene therapy - the accessibility, production, testing, and the importance of diversity and incl...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/uk1dxJe3VoY Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, meet with Dr. Elias Sayour from the University of Florida. While many are familiar with mRNA due to its COVID-19 vaccine application, Dr. Sayour discusses mRNA within the pediatric brain tumor landscape - including preclinical work, its delivery & distribution, as well as promising future opp...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/7NAibEpTA0w Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined by Dr. Mariella Filbin from Dana-Farber Cancer Institute/Boston Children's Hospital. Dr. Filbin discusses her expertise within DIPG including transcriptomics and epigenomics, as well as what is on the horizon for research - both challenging and exciting advances. Have any thoughts?...

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/Fd1flMgbfLw Listen in as our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined in this episode by Dr. Lisa Diller from Dana-Farber/Boston Children's Cancer and Blood Disorders Center. Dr. Diller discusses the possibilities of genetic testing for pediatric cancer predisposition syndromes in newborn screening programs, but with uncertain benefi...

WATCH THE VIDEO WEBCAST HERE: https://www.youtube.com/watch?v=nJZYz1XrsyY Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined in this episode by Dr. Andras Heczey from Texas Children's Hospital/Baylor College of Medicine. Listen in as they discuss Dr. Heczey's expertise & research in utilizing Natural Killer (NK) T-cells for pediatric immunotherapy treatment and the process of doing so. Hav...