The Startup Ideas Podcast

In this episode I bring Nick Vasilescu, co-founder of Orgo, back on the show to unpack the buzz around Grok 4.5. Nick makes the case for treating Grok 4.5 as a genuine AI co-founder inside harnesses like Hermes and OpenClaw, and he proves it live: spinning up cloud computers, wiring in tools, and building a full startup from idea to landing page to outreach. We race Grok 4.5 against GPT 5.6 Sol, t...

In this episode I sit down with Dan Shipper to see how he runs his work and personal life on OpenAI's Codex Desktop with the 5.6 model. He walks through his card-based email setup, daily feeds for his company and Slack, and the in-app browser that lets his agent collaborate with him inside tools like Proof. We build a small SaaS app live, called Turnaround, and use it to explore why maintenance is...

In this solo episode I lay out why I believe building agents is the new SaaS: software is shifting from helping you do the work to doing the work with you. I walk through a full playbook — find a niche, pick a workflow with a paycheck attached, shadow the human, spec the agent, build the minimum useful version, sell a pilot like labor, then productize the repeatable parts. I share live market exam...

In this solo episode, I lay out the six skills I believe stay valuable as AI grows more capable. I chose these six because each one is open to anyone, each one starts this weekend, and each one rises in value as AI improves. I walk through agents and local models, distribution, robotics, curation, the builder distributor, and IRL community building, with one concrete first rep for every skill. My...

In this episode I sit down with Amir to get tactical about running local AI models as part of a daily workflow. We center on GLM 5.2 from ZAI, how it stacks up against frontier models like Opus 4.8, and how a fusion approach lets you sequence a heavy thinking model with a lighter execution model for the best output at the lowest cost. Amir walks through setup in Cursor and Codex via OpenRouter, sh...

In this episode I sit down with George Lampropoulos, a 19-year-old founder who turns AI-built mobile apps into real revenue. George walks through his framework for reaching $10K a month—roughly $333 a day—starting with a simple, sellable idea you actually care about and ending with a distribution plan anyone can run. He shares the numbers behind WrestleAI (100K-plus downloads and close to $200K in...

In this solo episode, I walk through the implications of the ban of Claude Fable 5 — the most powerful model on the planet and the one I planned to build with — after the US government sent Anthropic a letter. I make the case for local AI by walking through the benefits: intelligence that lives on your own hardware, stays private, runs free after the hardware cost, and keeps working through bans,...

Get my Fable 5 prompt pack: https://startup-ideas-pod.link/fable5-prompt-pack In this episode I break down how to get the most out of Fable 5, the most powerful model I've ever used. I move past the benchmarks and go straight into tactical use cases, copy-and-paste prompts, and startup ideas you can build today. I walk through tournaments for copy and landing pages, an interview-before-build workf...

S/o Coderabbit for sponsoring today’s vid: https://startup-ideas-pod.link/code-rabbit On this episode I sit down with Professor Ras Mic to break down agentic loops. We define what a loop is, explain why well-known builders like Boris and Peter swear by them, and stay honest about who they truly serve. Mic argues that human-in-the-loop remains the strongest setup today, and he walks through the one...

Become an AI Native Organization: https://startup-ideas-pod.link/ai-native-org In this episode I sit down with Theo to unpack what becoming AI native truly means. We define an AI native org as people managing agents, agents reading and writing to the company, and the company growing smarter over time. Theo opens his actual workflows, walking through a working prototype, an auto-generated client pr...

In this episode, I sit down with Alex Finn for a full, screen-shared walkthrough of Hermes Desktop, the new desktop home for the Hermes AI agent. I open with a clear challenge: by the end, sell me on installing Hermes Desktop, show me real ways to make money and stay productive, and explain his move from OpenClaw. Alex tours every major surface — sessions, profiles, artifacts, skills, cron jobs, a...

In this solo episode I walk through Codex Sites end to end, building a real internal tool live so you can copy the exact workflow. I open by comparing Codex Sites with one-prompt tools like Replit and Lovable, then construct a Startup Ideas OS board in six prompts. Along the way I cover memory and persistent storage, safe actions, Codex skills, save-gates, and proving the loop so the app updates a...

In this solo episode, I break down the shift from a human-first internet to an agent-first one, where AI agents become the customers that discover, evaluate, pay, and recommend. I map the agent buying journey and the new infrastructure agents need: identity, tools, an inbox, memory, a wallet, and receipts. I ground it with concrete examples like AgentMail and Stripe's agent wallet, then show how t...

Live from Google I/O, I sit down with Logan Kilpatrick from the Google DeepMind team to unpack everything Google just announced and what it means for founders, developers, and anyone trying to build with AI right now. We dig into Gemini 3.5 Flash, the new Gemini Omni world model, the expanded Antigravity ecosystem, managed agents in the Gemini API, and the native Android app builder inside AI Stud...

I sit down with my friend Jonathan Courtney, a.k.a. Jicecream, to dig into the 9 biggest startup opportunities I see right now across B2C, AI, mobile, and IRL. We each pick ideas, trade reactions, and pressure-test them live. The conversation ranges from agent-first "action apps" to elder tech, third spaces, hobby retreats, pet health, AI-native media, and the case for selling AI "junior employees...

If you want more workflows and tactics to build a business with AI, check out this free workshop: https://www.ideabrowser.com/workshop I sit down with Andrew Wilkinson and we go deep on how he's restructured his work, his health, and his family office around AI agents. Andrew walks me through Deep Personality (an app he vibe-coded after running psychological screens on himself and his girlfriend),...

Nick agreed to personally set up your Orgo in a 15 min call: https://startup-ideas-pod.link/orgo_ai I sit down with Nick from Orgo to break down exactly how to run a one-person AI agent business that can realistically clear a few million dollars a year. Nick walks through the offer, the verticals worth chasing, the full software stack, and the live setup of an agent that manages other agents. We f...

Get started building your tiny AI Agent business with Genspark Claw: https://www.genspark.ai/?utm_source=po&utm_campaign=GregIsenberg In this solo episode, I share seven tiny, cash-flowing startup ideas you can build with AI in just a few prompts. I walk through how to use Genspark Claw, Genspark's new in-the-cloud agent product running Sonnet 4.6, and demonstrate two ideas I have already built (a...

I sit down with Meng To for his second appearance on the pod to dig into design md, Google's newly open-sourced format for capturing the soul of a design and porting it across every medium and tool. Meng walks me through a live demo of how he uses design md alongside skills, HTML references, and tools like Aura, New Form, Codex, and OpenClaw to ship landing pages, motion design, slides, and mobile...

I'm joined again by Imran Muthuvappa to walk through how to build your own AI Chief of Staff using a tool called Nebula. Imran shows me how to spin up specialized agents that handle the work a real chief of staff would do — surfacing team blockers, tracking project status, holding people accountable to offsite vision goals, running daily agenda briefings, and prospecting ICP leads. We also get int...

Limited BONUS: First 1,000 builders get $1,000. Claim yours while supplies lasts.: https://startup-ideas-pod.link/hyperagent I sit down with Howie Liu, co-founder and CEO of Airtable, to talk about the agent economy and the launch of HyperAgent. We walk through Sequoia's charts on AI agent deployment, the economics of token-based work versus human labor, and why frontier agents have crossed a thre...

I sit down with Riley Brown to get a hands-on tour of OpenAI's Codex, which he argues is the most powerful single interface for using AI agents today. Riley walks me through how Codex unifies vibe coding, knowledge work, browser use, computer use, and automations into one app, all running on GPT 5.5. I come in as a complete Codex skeptic who has spent most of my time in Claude Code, and Riley show...

In this solo episode, I walk through ChatGPT Images 2.0 and show exactly how to use it to build creative assets that move a business forward, from brand visual directions to UI mockups to apparel mockups and editorial illustrations. I share the AI tool that surprised me this week (Noscroll), hand over a startup idea I want someone to steal (a learn-to-draw app with AI feedback on every sketch), an...

I sit down with Imran Muthuvappa to get a hands-on walkthrough of Hermes Agent, a personal AI agent that ships with built-in memory, 40+ tools, and pre-installed skills out of the box. Imran walks me through why he migrated from OpenClaw, how to install Hermes on a Mac or even an Android phone via Termux, and how he cut his token spend by roughly 90% using OpenRouter. We get into agent design (one...

I go live and get my hands dirty with Claude Design, Anthropic's new design tool in research preview. Across roughly an hour, I run a real workflow end-to-end: pulling a product idea from Idea Browser, generating wireframes, iterating into visual designs, building a pitch deck, and attempting a 30-second video ad. I share my first reactions in real time and take feedback from the chat. By the end,...