Greg Isenberg
The Startup Ideas Podcast
Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out. For more startup ideas, we created a database of 30+ startup ideas you can take at https://gregisenberg.com/30startupideas
Be sure to visit the podcast's website and support the creator: www.gregisenberg.com
Author
Greg Isenberg
Category
Podcast website
Latest episode
Oct 26, 2026
Where to listen?
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Episodes
How to sell AI to Main Street (Full Playbook) 26.10.2026 44:20
Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP I sit down with James Dickerson, the Boring Marketer, who owns Diesel Dudes, a mobile diesel repair business in Charlotte, North Carolina, and spent years running agencies for local businesses. James shows how to sell AI-built funnels to Main Street trades businesses doing $2 million to $20 million a year, starting with a Bo...
Amazon & Delta Are Blocking AI Agents. How to Win Anyway. 21.10.2026 31:13
In this solo episode, I break down the war on AI agents, from Amazon blocking Meta's Muse to Delta treating outside booking agents as unauthorized automated activity to Yelp charging agents for access. I share how I think about an agent, as a customer with a credit card who reads your site instead of looking at it, and the ladder of trust that runs from research to prepare to pay. Then I walk thro...
Making $$$ with Meta Muse AI 19.10.2026 24:34
Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP In this solo episode, I break down how to make money with Meta Muse by mining Facebook groups, Marketplace, and Instagram to match buyers with sellers. The idea came after my wife and I had a baby and the agency we hired for a night nurse admitted it found candidates in Facebook groups. I demo Muse finding night nurses at $3...
Gemini 4 Argon: AI Marketing, 3D Printing and SaaS 15.10.2026 30:50
Gemini 4 Argon is LIVE, Google's most advanced AI model, try it for yourself: https://startup-ideas-pod.link/gemini4-argon In this solo episode, I share what I learned after a week with Gemini 4 Argon, Google's new frontier model. I show three places it shines: marketing with AI, physical AI, and complex engineering, with a real build for each. You'll see Argon rebuild my holding company's website...
8 GitHub Repos To Go Viral and Make Money 08.10.2026 24:29
In this solo episode, I walk through eight GitHub repos and AI skills that I test at night and on weekends. The list covers launch videos, social research, local voice and dubbing, editable decks, agent teams, lead-magnet tools, idea stress-testing, and design guidance. For each one, I explain what it does, how I'd set it up, and one concrete way to use it to make money or run a business more easi...
How Will People Make Money in the AI Age? 06.10.2026 25:17
In this solo episode, I walk through the 13 businesses I think are left to build in the agentic era. I believe that in a world of agents and abundance, owning the right assets puts you in a better position. For each business, I explain what it is, why it holds up in a world of agents, and one or two examples, from Othership's sauna clubs to Osmo's window-cleaning robots. This episode gives you a m...
Become a $1M/yr FDE (Full Course) 01.10.2026 53:59
Google's most advanced audio models are LIVE, try them for yourself: Gemini 3.8 Live: https://startup-ideas-pod.link/gemini-3.8-live Gemini 3.5 Transcribe https://startup-ideas-pod.link/gemini-3.5-transcribe Gemini 3.5 Live Translate: https://startup-ideas-pod.link/gemini-3.5-live-translate In this episode, I talk with Vas from Varick about what it takes to put AI to work inside a real company. Va...
OpenAI DevDay: Dots, Agents & $100B Opportunities 29.09.2026 18:56
I watched almost 60 minutes of Sam Altman on stage at OpenAI Dev Day 2026. Out of 20-plus launches, I pick the three or four that I think can make people billions of dollars in aggregate. I break down Dots, OpenAI's personal agent platform, plus the Decisions API, the Agents API with computer use, and Sign in with ChatGPT. I also share my four-step framework for building in this world and two busi...
$5T opportunity: AI Roll Ups 28.09.2026 29:49
In this solo episode, I break down the $5 trillion wave of small businesses set to change hands as their owners retire, and why AI agents make this wave a real opening for solo founders. I walk through how Thrive Holdings and General Catalyst buy accounting firms, property managers, and support centers, then run AI agents inside them to lift margins. Then I show how I'd run a one-person holding co...
Muse AI Connectors: The Next App Store Moment? 24.09.2026 26:15
In this solo episode, I break down the huge business opportunity because Meta has opened Muse, its personal AI agent, to developers. You can now submit a connector, which lets Muse use your service when someone asks it for help, and I think this could be the app store moment for AI. I explain how a connector works, share four startup ideas you can build on one, and cover how to get customers beyon...
The Right Way To Write With AI 21.09.2026 1:09:34
Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP In this episode I speak with Nicholas Cole about the real value of everything you write on the internet. Cole has 15 years of experience as a nonfiction writer and ghostwriter, and he runs the SaaS platform Typeshare. He gives me a simple model with three tiers of content: commodity, personality, and original. He also explai...
Jev is HERE. How to use it 18.09.2026 28:24
In this episode, I talk with Ryan Vogel about Jev, a new type of AI built for classification. Ryan shows how Jev takes an input plus an output schema and returns a probability for each choice in about 200 milliseconds. He demos Jev sorting 1,700 emails for 18 cents total, then covers lead scoring, support routing, video clipping, and browser control. I push him on the startup angle: find a busines...
Instinct AI: The AI Assistant for normal people 15.09.2026 27:30
I sit down with Remy to go through Instinct, the new invite-only personal agent that runs inside iMessage. Remy shares his raw chat history on screen: a haircut booking in Copenhagen, a restaurant reservation, a Bali visa on arrival, and an Emirates Skywards sign-up. We cover the parts that impress us, the points where the agent hits a wall, and the privacy questions that stay open. By the end of...
Building a Software Factory that actually works (Full Course) 14.09.2026 31:29
Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP I welcome Ras Mic back to the pod to explain the phrase "software factory." Mic shares his screen and walks through the exact system that he runs today. His factory has four steps: isolate, build, prove, and ship. He keeps the whole system in five or six markdown files, so it works with any model and any harness. By the end...
You're using GPT-6 Astra WRONG 10.09.2026 22:52
I talk with Ras Mic about GPT-6 Astra. We skip the game demos and the 3D toys, and we focus on use cases to earn money or improve products. I share 9 Astra prompts that I posted publicly, and Greg Brockman reposted. Ras then shows his hardware project: he moved from a speaker idea to a parts list, a Blender layout, and merged code in about 30 minutes. The takeaway is simple: use this model for the...
Local AI Clearly Explained 08.09.2026 38:46
I run this episode solo. I explain local AI in plain terms: the model runs on hardware I control, and a cloud model runs somewhere else. I map the four pieces of the local AI landscape — the model, the warehouse, the software, and the workflow — and I define the words that beginners meet first: parameters, tokens, context window, quantization, and GGUF. I walk through the Google open model stack (...
These 5 Github Repos are a goldmine 02.09.2026 24:43
On this solo episode, I review five free, open source GitHub repos that help you build products, make money, or save time: Peter Yang's No AI Slop Skill, the CRM by TryComp AI, Video Use by browser use, SkillSpector by NVIDIA, and Phone Harness. For each repo I explain what it does, why it matters, how to install it, and the first small workflow to try. I close with a simple three-step method: ins...
Making $$$ as a Marketing Engineer 31.08.2026 35:18
In this solo episode I explain a role that I call the marketing engineer. I believe this person becomes one of the most valuable hires in tech in the next 18 to 24 months. I define the job, I show the four eras of marketing that lead to it, and I give the tool stack that makes it work. I use a commercial HVAC software company as a worked example, and I list six systems that a marketing engineer bu...
WebMCP clearly explained (and how to make $$) 26.08.2026 28:58
Vinny is back on the pod, and he explains WebMCP. WebMCP puts MCP tools inside the browser UI, so any agent that you bring can read a page and act on it. Vinny demos an espresso gear store where his agent compares two machines, checks the counter width, matches accessories, adds an item to the cart, and applies a coupon. Together we map the agent-native options, from headless APIs to in-app agents...
Screensharing top takes in AI/startups 25.08.2026 41:17
On this week’s SIP Live we dive deep on the X timeline to give each post a sip or a skip, and we answer questions from the chat. This episode covers AI-native operations, a baby food app that earns a million dollars a month, iMessage agents, human customer support as a brand advantage, small teams, reading habits, and sales advice for builders. Listeners get concrete first steps, business ideas th...
Grok Bot: make a 1 person company with agents 21.08.2026 44:21
I sit down with Billy Howell for an inside look at a real business that runs on Grok Bot agent teams. Billy tests hundreds of tools for The Rundown, and he uses Grok Bot to run his local newsletter, The Arlington Bagel, which goes to 6,000 readers every Thursday. He walks me through his chief of staff bot, his research and sales agents, and the routines that move work forward while he sleeps. We c...
You need to be skillsmaxxing (10x your Claude/Codex) 19.08.2026 32:27
Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP I talk with Remy, known online as AI with Remy, about agent skills and how to share them across a whole team. Remy explains that a skill is an SOP for AI: a markdown file that teaches Claude your exact way to do a task. He then shows his system. He keeps his team skills in one GitHub repository, and he installs that reposito...
How to use Claude Code better than 99% of People 17.08.2026 48:10
Get Claude Code: https://startup-ideas-pod.link/claude-greg In this solo episode I lay out the exact system I use to turn Claude Code into what I call an AI employee. My premise is simple: give Claude the same things you would give a person joining your company (a workspace, memory, a brief, a clear ticket, eyes, review, a schedule, and permissions). I build the whole setup live around a real idea...
How to Build an AI-Native Company in 2026 12.08.2026 48:28
I sit down with Allie K. Miller to talk about the shift from managing AI agents to enabling them. Allie runs a workforce of 34 AI agents led by an AI chief of staff named Simon, plus six directors named after Friends characters. She shares her three-word prompt, her daily AI diary, her AI watchdogs, and her rule to build the factory before the product. We then debate the future of software: why en...
Making $$$ selling to AI Agents 10.08.2026 34:10
In this solo episode I break down Cloudflare's AI agent announcement in plain English and explain why I see it as the new business model for the internet. I walk through AI crawl control, pay per crawl, the monetization gateway, and the x402 payment rail, and I show how a single request turns into a transaction. From there I give three startup ideas built directly on top of this shift: a niche dat...
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