The Pituitary World News Podcast

In today’s LIVE-TALK podcast, we chat about our recently published series of books.  We highlight Dr. Blevins’ prolific writing output in the PWN self-published book series, with five titles on pituitary adenomas, diabetes insipidus, Cushing’s, hypopituitarism, and pituitary disorders; a TSH-producing tumor book (in editing); a prolactinoma volume heading to the publisher; and an acromegaly book p...

Our live talk sessions of the pituitary and adrenal podcasts continue with this extremely informational conversation on hypothalamic obesity.  If you are interested in learning more about his devastating disorder, please listen to Dr. Blevins as he shares his insights and extensive expertise on its causes, new treatments, and latest developments.   He explains the underlying biology: fat cells pro...

In today's podcast, Dr. Blevins and I discuss the health insurance landscape as it relates to medication, tests, and procedure approvals and denials. Dr. Blevins gives us an unfiltered look at what it is like to deal with these challenges and their effects on the practice of medicine and medical decision-making. Don't miss this segment and stay tuned for more of these insightful, genuine, and ungu...

In today’s podcast, we’ll dive into the personal journeys of two very interesting and accomplished people who have dealt with this disease and will share their experiences, and importantly, their opinions, shedding light on symptoms, diagnosis, the struggles and frustrations, and the importance of awareness to affect early diagnosis and to manage the condition effectively.   I’m delighted to welco...

In today's podcast, we talk to Anne Vaslin Chessex,  Global Program Leader at   Debiopharm Internationa l. In this dynamic chat, we explore Debiopharm's innovative three-month formulation of Octreotide for acromegaly, highlighting the science, clinical trials, and patient benefits. Gain insights into drug development, patient-centered approaches, future treatment options, and learn how to particip...

Today we welcome to our podcasts Dr. Francesca Galbiati who recently joined the California Center for Pituitary Disorders at UCSF, where she cares for patients with pituitary tumors, acromegaly, Cushing's disease, and related hypothalamic conditions. She is originally from northern Italy and the first in her family to attend college, her path into medicine was driven by a love of science, a desire...

In today's podcast, Crinetics co-founders Dr. Scott Struthers and Dr. Steve Betz share their views and experiences in drug discovery and development, revealing what it really takes to bring a new medication from concept to patients. We discuss their recently approved drug for acromegaly, Paltusotine (Palsonify™), along with their pipeline plans for Cushing's disease and congenital adrenal hyperpla...

In the latest episode of the Pituitary World News podcast, Jorge D. Faccinetti sits down with Dr. Markus Johnsson, Senior VP of R&D at Camurus , to explore the fascinating world of FluidCrystal® technology. This innovative approach promises to revolutionize the way we think about drug delivery, providing long-lasting solutions for chronic diseases particularly for people with acromegaly. Marku...

En el podcast de hoy hablamos con el Dr. Manel Puig Domingo sobre un estudio innovador que él encabezó y que se describe en un artículo reciente publicado en la revista PITUITARY. El artículo plantea la posibilidad de que los algoritmos de IA y el aprendizaje automático podrían proporcionar un enfoque revolucionario para el diagnóstico temprano de esta enfermedad compleja, cuyo diagnóstico actualm...

In today's podcast we talk with Dr. Manel Puig Domingo about an innovative study he spearheaded and outlined in a recent paper published in the journal PITUITARY.  The paper raises the possibility that AI algorithms and machine learning could provide a game-changing approach to the early diagnosis of this complex disease, which now takes an average of 6 to 10 years to diagnose. The paper outlines...

In today's podcast, Dr. Kevin Yuen, a world-renowned neuroendocrinologist, frequent PWN contributor, and medical director of the Barrow Neurological Institute , discusses Crinetics' new acromegaly drug Paltusotine (Palsonify™) . The drug was recently approved by the Food and Drug Administration. Dr. Yuen explains how this new medication works and provides an excellent clinical perspective on his v...

Can Artificial Intelligence make medical research easier to understand?  This AI-generated content (we hesitate to call it a traditional "podcast") was brought to our attention by one of Dr. Blevins' patients, who discovered it in a Facebook patient group. The creator used a well-known AI platform to analyze one of Dr. Blevins' recently published papers on PWN, translating the complex medical lang...

In today's podcast, Dr. Lewis Blevins dives into the fascinating findings from a study by Corcept Therapeutics on the prevalence of hypercortisolism in people with type 2 diabetes. Results from this study, called CATALYST , were recently published by Corcept and presented at various scientific and medical conferences. Dr. Blevins explains the findings and offers his expert insight.  

In today's podcast, Dr. Lewis Blevins discusses relacorilant, a drug currently in development by Corcept Therapeutics for the treatment of hypercortisolism. Clinical trials to date have shown encouraging results, with improvements in blood pressure, glucose control, weight, and body composition. Corcept Therapeutics specializes in developing drugs that modulate the glucocorticoid receptor.   Stay...

This is a very informative discussion about the new indications of the  Cushing's Drug Isturisa® (osilodrostat) with Dr. Mario Maldonado, who heads global development for endocrinology at Recordati Rare Diseases.  The Food and Drug Administration recently approved the drug for endogenous hypercortisolism (excessive production of cortisol in the body).  If you want to learn more about this fascinat...

CAM2029 represents a significant advance replacing cumbersome deep muscle injections with a user-friendly pen device similar to modern insulin and GLP-1 delivery systems. The practical benefits are remarkable: monthly administration, storage at room temperature, and no more traveling with cooling equipment. These improvements may seem incremental to outsiders, but for patients managing acromegaly,...

We are delighted to welcome Dr. Leena Shahla to the Pituitary Podcast. She is the director of The Duke Pituitary Program. Today she joins PWN co-founder and medical director of the California Center for Pituitary Disorders at UCSF, Dr. Lewis Blevins, for an in-depth discussion about pseudo-Cushing's syndrome. In the Duke Health web portal, Dr. Shahla says endocrinology captured her heart because i...

In this podcast, Dr. Blevins reviews the side effects of dopamine agonist drugs. These are drugs that activate certain types of cells in the brain to regulate various functions, including hormone regulation, movement, and motivation. Dr. Blevins's discussion focuses on the drug cabergoline and its side effects, citing several research studies. This is a fascinating review of side effects you won't...

Sometimes conversations take interesting turns and often lead to surprising and unexpected discussions. If you're a regular listener of the Pituitary Podcast, you may have caught a few of our live broadcasts where these unscripted discussion are common. Today I'm joined by Risa August, a patient and advocate and a frequent guest sharing her work, adventures and advocacy efforts, for one of those e...

Today's podcast is about an important Chiesi Rare Diseases initiative to learn more about the psychological, social, and emotional health issues facing acromegaly patients.  We talked to Stuart Siedman, Chiesi's Vice President of advocacy.  Stuart has an extensive background in rare diseases and a personal connection as an advocate.  This is an important subject. We hope you will help by participa...

In today's podcast, we are excited to welcome Dr. Joanna Spencer-Segal, a research assistant professor at the Michigan Neuroscience Institute and an assistant professor in the Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes at the University of Michigan. She joins Dr. Lewis Blevins and me to discuss the promising new treatment options for acromegaly. Our conver...

I am pleased to welcome Dr. Scott Pescatore to the Pituitary Podcast.  In today's podcast, we discuss some of the work being done in the pituitary and adrenal space.  Dr. Pescatore's - and other industry leaders we've featured on the Pituitary Podcasts - opinions and points of view are essential to developing current and future therapies and potential new treatments affecting access to medications...

Today's podcast features my chat with Dr. Mario Maldonado, Head of Development and Global Endocrinology at Recordati Rare Diseases .  Dr. Maldonado brings a wealth of experience and a great perspective on drug development. He was involved in developing both pasireotide and osilodrostat, two essential compounds used in drugs to treat Cushing's.   Listen to this fascinating talk with one of the most...

Mental health is an ongoing challenge for people dealing with Pituitary conditions, from brain fog to anxiety to downright depression. These and other emotional issues are some of the most talked about and commonly related when people talk about what it's like to live with one of these devastating conditions.  Today's podcast brings together two leading experts in mental health and pituitary disea...

Today's podcast covers my conversation with Jill Sisco, president of the Acromegaly Community, about the recent meetings with the Food and Drug Administration (FDA), the US governmental entity responsible for approving new medications.  Our conversation focuses on the original meeting held in 2021 and a recent listening session where the AC provided additional feedback to the FDA.  These meetings...