The Open Loop

In this episode of The Open Loop, Chay Carter is joined by Daniel Powell, Founder of Spark Biomedical .   Daniel shares his journey from consulting into more than two decades in neuromodulation, with experience across spinal cord stimulation, DBS, vagus nerve stimulation, and non-invasive auricular neurostimulation.   This is a practical conversation about building clinically validated neurotechno...

In this episode of The Open Loop, Chay Carter is joined by Ken Mariash, CEO of Sinaptica Therapeutics . Ken shares how Sinaptica is developing a non-invasive, personalised neuromodulation therapy designed to slow the progression of Alzheimer’s disease by targeting the brain networks involved in memory. This is a practical conversation about moving beyond amyloid-only thinking and looking at Alzhei...

In this episode of The Open Loop, Chay Carter is joined by Laura Avonius, Founder and CEO of Audicin . Laura is a Finnish entrepreneur, composer, and digital health leader building at the intersection of music, neuroscience, and nervous system regulation. She shares how her journey from behavioural science, tech, and music led to the creation of Audicin, a company developing neuroscience-based aud...

In this episode of The Open Loop, Chay Carter is joined by Dr Nandan Lad and Amaza Reitmeier, the executive leaders behind Pharaoh Neuro. Nandan is a neurosurgeon at Duke and the inventor behind Neurapheresis, while Amaza brings nearly 25 years of leadership experience from Medtronic, including deep experience in brain therapies and DBS. This is a practical conversation about Pharaoh Neuro’s missi...

In this episode of The Open Loop, Chay Carter is joined by Anoop Antony, Founder and CEO of NeuroX. Anoop shares his journey from psychology and cognitive neuroscience into EEG, brain health, neurofeedback, photobiomodulation, and wearable neurotechnology. This is a practical conversation about making brain health more accessible, understandable, and useful outside traditional clinical and researc...

In this episode of The Open Loop, Chay Carter is joined by Jordi Parramon, a neurotechnology operator, investor, and founder of Nexus NeuroTech Ventures.   Jordi brings more than 27 years of experience across medical devices, health tech, and venture, with leadership roles spanning Boston Scientific, Verily, and a portfolio of neurotech companies including Cala Health, INSIGHTEC, Rune Labs, Lotus...

In this episode of The Open Loop, Chay Carter is joined by Jennifer Ernst, founder and former CEO of Tivic Health (now Valion Bio).   Jennifer shares the story behind Tivic’s journey, from consumer bioelectronics and non-invasive stimulation to FDA clearance, retail launch, IPO, supply chain disruption, and a major pivot into biopharma.   This is a practical conversation about the rollercoaster jo...

In this episode of The Open Loop, Chay Carter is joined by Dr George Harston, Chief Medical and Innovation Officer at Brainomix.   George shares how Brainomix is building clinical AI software to support treatment decisions in stroke and fibrosing lung disease, helping clinicians extract meaningful information from medical scans and use it in time-critical patient pathways.   This is a practical co...

In this episode of The Open Loop, Chay Carter is joined by Dan Rizzuto, President and CTO at Nia Therapeutics.   Dan shares how Nia is developing a closed-loop neurostimulation system designed to help patients with memory loss, combining implantable sensing, machine learning, wearable components, and personalised stimulation.   This is a practical conversation about the future of cognitive BCIs, w...

In the first episode of The Open Loop, Chay Carter, Founder of Carter Sciences and Reccy Neuro is joined by Dr. Owen Scott Muir, Interventional Psychiatrist, Co-founder & Chief Medical Officer at Radial.   Owen shares his personal journey through bipolar disorder, his experience as a clinical trial participant, and how those experiences shaped his mission to build the future of “brain medicine...