The Human Upgrade: Biohacking for Longevity & Performance

Biohacking isn’t just food + exercise, it’s about fixing the invisible disruptors wrecking your biology. EMFs, mold, toxins, mitochondrial stress, these are the real reasons you still feel tired, foggy, or inflamed even on a perfect diet. I’ve been there. I lost 100 lbs, built Bulletproof Coffee, and discovered why food alone isn’t enough. In this video, I’ll show you what’s actually holding back...

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. T This episode covers: •  Longevity Scores Are Going Mainstream Elegant Hoopoe’s new clinics are using 56 biomarkers to track biological aging — and early users are reporting up to six years reversed in under two months. Could scoring systems replace reactive healthcare? Source: Morningstar via PR Newswire — https:/...

Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You’ll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain an...

Nicotine isn’t just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you’ll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from f...

These "toxic foods" are one of the biggest hidden threats to your health and most people are eating them every single day without realizing it. These cheap industrial foods are marketed as “healthy,” but the truth is they damage your cells, drive inflammation, and speed up aging. In this video, I’m exposing the dark history behind how they ended up in our food system, why regulators don’t protect...

What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water?  This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better.  Watch this episode on YouTube for the full video experience:  https://www.youtube.com/@DaveAspreyBPR &...

AI is transforming medicine at a speed never seen before. In this episode, you’ll discover how digital twins and artificial intelligence will revolutionize drug discovery, eliminate human trials, and personalize your biology for longevity and high performance. Host Dave Asprey breaks down how AI can now simulate virtual cells and tissues, running clinical experiments in minutes instead of years to...

Most people think about heart disease and metabolism when they talk about longevity, but too few talk about joint health. In this episode, you’ll discover how to biohack your joints to prevent pain, reverse damage, and move like you’re decades younger. Host Dave Asprey reveals how functional movement, core stability, and recovery can transform joint health, helping you maintain pain-free performan...

Remote work might feel like freedom, but your biology disagrees. In this video, I break down how your work-from-home setup is hijacking your hormones: crushing testosterone, spiking cortisol, and wrecking insulin sensitivity. I’ll show you exactly how posture, light, movement, and meal timing secretly control fat gain, energy crashes, and libido drops... and how to take back control without quitti...

Upgrade your week in just 10 minutes with D(AI)ve Asprey’s essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom.  This episode covers:   •  Apple Cider Vinegar Myth Busted   A weight-loss study just got retracted. ACV will not melt fat, but it may blunt glucose spikes or ease digestion when diluted in water before carb-heavy meals...

Gravity may be the most ignored signal in human biology, and it could be the missing key to unlocking fat loss, brain optimization, and true longevity. In this episode, you’ll learn how Earth’s pull shapes your metabolism, mood, and resilience, and discover practical hacks to fight “gravity intolerance” so you can perform better, live longer, and upgrade every system in your body.  Watch this...

Most people chase fat loss, focus, and energy with caffeine or stimulants, but the real key to brain optimization and human performance is a pharmaceutical nootropic that activates your wakefulness circuits without jitters or a crash. In this episode, you’ll learn how Modafinil upgrades mitochondria, sharpens neuroplasticity, improves metabolism, and extends longevity with evidence-based tools use...

Most people are struggling with fat loss, low energy, and hormone chaos—and they don’t even realize the real problem isn’t their diet or workout plan... it’s their liver. In this episode, I break down how your liver controls fat-burning, energy, and hormone regulation—and why things like poor bile flow and mineral deficiencies are sabotaging your results. I’ll show you how to fix your metabolism b...

Upgrade your week in just 10 minutes with D(AI)ve Asprey’s essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. Each story includes trusted source links—so you can check the facts.  This episode covers:  - Rapamycin’s Reality Check:   A sweeping new review (September 24) finds that the promise of rapamycin for longevity in healthy adu...

Your mitochondria are the power plants of your cells, and when they break down, you lose energy, brain sharpness, and resilience against aging. In this episode, you’ll learn how to hack your mitochondria to supercharge human performance, prevent decline, and extend longevity with tools that are natural, effective, and backed by decades of research.  Watch the condensed video highlight version...

Your brain isn’t as rational as you think, and that blind spot can wreck your decision-making, relationships, and even your health. In this episode, you’ll learn how to spot the hidden cognitive traps that even the smartest people fall for, and how to upgrade your thinking so you can perform better, live longer, and make choices that actually serve you.  Watch the condensed video highlight ve...

If you feel like your brain's stuck in first gear, losing focus, forgetting simple things, feeling mentally sluggish—you’re not alone. I lived with brain fog for 15 years while building companies in Silicon Valley, and no productivity hack or double espresso fixed it. In this episode, I’ll show you how to clear brain fog at the cellular level by restoring mitochondrial energy, ditching brain-damag...

Confidence is biology you can hack. In this episode, you’ll see how confidence builds inside your brain, rewires through neuroplasticity, and connects directly to mitochondria, metabolism, and human performance. You’ll get tools that reprogram fear, regulate your nervous system, and turn stress into fuel so you build radical confidence that lasts.  Listen to this classic with host Dave Asprey...

If you’ve ever cringed at the sound of your own voice or struggled to hold attention in a room, this episode will change the way you speak and how others respond to you. You’ll discover how vocal tone, breath, and emotion act as biological levers you can train to improve your health, extend your longevity, and build magnetic charisma.  Watch the condensed video highlight version of this episo...

If you’ve ever felt crushed by stress or trapped by fear, this episode gives you the science and strategies to break free. You’ll learn how Olympic-level coaching can rewire your brain for resilience, unlock peak human performance, and extend your longevity through proven biohacking tools.  Watch the video highlight version of this episode (and much more!) on YouTube:  https://www.youtub...

Most men think declining testosterone is just “part of aging”, but that’s a lie Big Pharma sold you. In this video, I break down exactly how I raised my testosterone in my 50s without injections, drugs, or TRT. These are the same biohacks I used to turn my energy, drive, and strength around, naturally. I’ll walk you through how your diet, your sleep, and even the light in your bedroom could be sab...

Want to biohack your biology with nature’s most powerful anti-aging compounds? In this episode, you’ll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet’s pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and lo...

Want to improve memory, unlock neuroplasticity, and achieve sharper brain optimization? This episode reveals how Transcendental Meditation (TM) functions as one of the most powerful nootropics for human performance, longevity, and resilience.  Watch this episode on YouTube for the full video experience:  https://www.youtube.com/@DaveAspreyBPR   Host Dave Asprey sits down with neuros...

Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization.  Watch this episode on YouTube for the full video experience:  https://www.youtube.com/@DaveAspreyBPR   Host Dave Aspr...

What if the foods you think are healthy are actually disrupting your biology? From sugar marketed as a performance tool to “whole grains” that drive cravings, this episode uncovers how hidden traps in modern nutrition can hijack your brain, wreck your metabolism, and accelerate aging. You’ll learn how to rethink daily eating so it fuels energy, resilience, and long-term health instead of quietly s...