The Human Upgrade: Biohacking for Longevity & Performance

Today, we’re digging into specifics about food that you haven’t heard on the show before. This one may very well influence you to rethink your “healthy” diet and change how you feel about food completely. To get there, I’m excited to welcome back Teri Cochrane, an integrative practitioner and pioneer in personalized healthcare.  Teri is the founder of the Global Sustainable Health Institute®...

Meet the man who’s making leaps forward in functional movement training.  Ben Patrick (aka the Knees Over Toes Guy) went from chronic knee issues to becoming a dunking sensation with his remarkable 42-inch vertical leap. His journey led him to discover the unconventional “knees over toes” method. He now trains to reverse joint pain and defy aging. In this episode, Ben shares his three game-ch...

Today, we're learning how to Biohack like a Woman. And trust me, it's not about counting calories or giving up your favorite foods; it's a whole new paradigm. I'm thrilled to introduce you to our incredible guest today, someone I've had the privilege of working with for several years—Aggie Lal aka Biohacking Bestie.  Aggie is not your average biohacker; she's a public figure, bestselling auth...

Today’s very special episode comes from inside Kimbal Musk’s kitchen, where I get a hands-on look at his passion for cooking, community, and regenerative farming. Kimbal Musk is a South African restaurateur, chef, entrepreneur and a board member at Tesla Inc. and SpaceX, companies led by his brother, Elon Musk.  Outside of the tech space, Kimbal is the force behind The Kitchen Restaurant Grou...

Today’s guest is not a scientist but a true visionary. Gary Vaynerchuk (aka Gary Vee), is a self-made entrepreneur and digital marketing pioneer. He started his business journey with a lemonade stand at age seven. Now, he’s a prolific content creator, best-selling author, and the co-founder of the massive digital agency VaynerMedia.  What I love about Gary is that he leads with integrity, opt...

I'm excited to welcome back Dr. Steven Gundry to The Human Upgrade for his sixth appearance, a tribute to his remarkable insights and ongoing research. Dr. Gundry, a true pioneer, is renowned for his books like "The Plant Paradox" and his groundbreaking work on lectins, changing how we understand our body's reaction to food. He's also a top cardiothoracic surgeon and a leader in robotic cardiac su...

On today’s Upgrade Spotlight episode, we’re talking all about NAD+. In the biohacking world, everyone and their mother has heard of NMN and NAD+, but there’s more to it than meets the eye.  To get into the nitty gritty of NAD+, we’re joined by Dr. Gregory Kelly, a naturopathic physician and the lead product formulator at Neurohacker Collective, also known as Qualia. I’m an advisor to the comp...

Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered.  Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marqui...

Dr. Anthony Youn, aka “America’s Holistic Plastic Surgeon,” is an expert in your face. He joins us to answer some burning questions… Can plastic surgery actually be holistic? Can you turn back the clock without going under the knife? And… What work should I get done to my face? Today, we’re talking all about how to hack your face and save your skin.  Dr. Youn is a nationally-recognized, board...

Get ready for this important download on a fascinating biohacking compound you haven’t heard me talk about before: Urolithin A. It’s a postbiotic that supports the mitochondria, and it’s backed by impressive studies on longevity, anti-cancer effects, cognitive function, and muscle strength. In fact, this compound has earned a place in my permanent stack—which you know isn’t easy to pull off. Today...

In this special end-of-year "best of" episode, you'll learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity. Mark Hyman, M.D., joins Dave in Austin to talk all things longevity. Driven by his desire for a healthier, longer life for himself and others, Dr. Mark immersed himself in the lat...

In this episode of The Human Upgrade you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people  thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what real...

This episode is a deep dive into the heart of modern fitness, led by one of its most influential figures. Joining me today is Lavinia Errico, the visionary co-founder of Equinox Fitness Clubs. Lavinia isn't just a pioneer in the fitness industry, she's a passionate advocate for a life that's healthier, more fulfilled, balanced, and brimming with joy.  She's dedicated to helping others achieve...

Today is a long-awaited show with none other than Bryan Johnson, an entrepreneur, venture capitalist, author, and professional rejuvenation athlete on a mission to discover the next evolution of humankind. While Bryan is well known in the longevity space, I’ve been a fan of his work for years because of his neuroscience background.  Bryan started a company called Kernel, which makes devices t...

Coming to you live from Austin, Texas, I can’t wait for you to meet Dan Freed—a man who’s journeyed from the hot kitchen of high-end cooking to the frontier of brain improvement. Dan’s the founder and CEO of Thesis, a company that's revolutionizing the way we think about our brain's potential, and his journey is one of resilience and innovation.  Picture this… A kid struggling with focus thro...

Cynthia Thurlow  joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause. Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Maste...

Dive into a captivating exploration of human biology and connection—erotic blueprints. Discover four primal drivers: fear, food, friends, and fertility, with a unique focus on fertility in this episode. Miss Jaiya, a leader in somatic sexology, sheds light on the intimate realm of human relationships and pleasure. As an award-winning somatic sexologist and creator of The Erotic Blueprints® Framewo...

I am excited to chat with a longtime friend who is a fellow expert in how to make your brain work better. Jim Kwik is an absolute wizard when it comes to maximizing your brain's potential. We go way back, over a decade, and I can vouch for his incredible expertise in the realm of cognitive enhancement. He also has just released an expanded addition to his best-selling book, Limitless, where he del...

Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wa...

I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus.  But what's especially exciting is how John has evolved his insights to address the changing dynamics betw...

Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention. The discussion unravels the significance of the number 8, explores the mechanics behind Lynne's intention exp...

How about we have a conversation with one of the most spiritually influential living people on earth? Yes, you heard that right!  Today's guest was bestowed with this honor by Watkins MindBodySpirit, and if that's not impressive enough, AgeNation awarded him a Life Achievement Award. Today, we have the incredible privilege of sitting down with a true luminary in the world of spirituality, hea...

Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg. In this episode, we explore the incredible journey of Kevin Warwick, who became a cyborg ove...

Today, we talk about one of my favorite biohacking topics: hormones. Starting way back before I first had kids, I’ve studied hormones as they relate to fertility – leading to the first of just a few books over the years, The Better Baby Book. And it's been an area of passion ever since because hormones also control your mood and your energy levels and your happiness. So I wanted to invite Dr. Fran...

Today, let's delve into a topic often overlooked but crucial for our overall health: our skin. Over the past decade, I've started seeing our skin as more than just a protective layer; it's a major organ, just like our liver or heart. Its health goes beyond appearances – it profoundly influences our biology and well-being. Today, I welcome Carolina Reis Oliveira, the founder of OneSkin, a skin heal...