Epistemix
The Flux by Epistemix
Welcome to The Flux - where we talk data, decisions, and stories of people asking the what-if questions to create an intentional impact on the future.
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Episodes
From Archaeology to Algorithms: Exploring Human Systems with Agent-Based Models with Stefani Crabtree 11.03.2026 25:53
At the Complex Systems Society of the Americas conference in Santa Fe, host John sits down with archaeologist and complexity scientist Stefani Crabtree to explore the unexpected paths that lead to agent-based modeling. From studying theater and music to traveling the world on a fellowship and working in contract archaeology, Stefani’s journey into computational modeling was anything but linear. In...
Big Data, Little Brain: Making Structural Components Known and Emergent Outcomes Clear with Paolo Gaudiano 13.10.2025 35:40
In this episode of The Flux, host John Cordier, CEO of Epistemix, sits down with Paolo Gaudiano, a complexity scientist turned DEI innovator, whose journey spans neuroscience, agent-based modeling, and the business of inclusion. Together, they explore what happens when we stop treating diversity as a box to check and start understanding it as an emergent property of complex systems. Paolo shares h...
Strategic Innovation in Public Health with Les Craig 08.07.2025 27:43
Les Craig joins us to discuss how simulation and synthetic data are changing the way organizations prepare for infectious disease outbreaks. From helping public health leaders visualize complex scenarios to enabling pharmaceutical companies to explore new R&D pathways, Les explains how advanced modeling technology empowers faster, smarter decisions. This episode unpacks how simulation can move...
Designing for Uncertainty with Mickey McManus 23.06.2025 51:43
In this episode of The Flux, host John Cordier sits down with innovation pioneer Mickey McManus to explore what it means to design for uncertainty in a world where complexity is the norm. Mickey draws on decades of experience from leading Maya Design and shaping decision-support tools for DARPA, to helping build the Future of Learning team at Autodesk to share insights on how human-centered design...
The Role of Sentiment and Social Dynamics in Public Health Models with Philippe Giabbanelli 09.06.2025 42:28
In this episode of The Flux, we explore how modeling trust, belief, and social sentiment can unlock deeper insights in public health. Our guest, Philippe Giabbanelli, shares how agent-based models are evolving to capture not just behaviors, but the opinions and social dynamics that drive them like vaccine hesitancy or trust in institutions. We discuss the challenges of representing complex human p...
Glory Days of Modeling: Dan Eichelsdoerfer on Building Macrocosm 19.05.2025 41:25
In a world full of linear thinking, Dan Eichelsdoerfer is building a company grounded in complexity. In this episode, Dan joins The Flux to discuss why agent-based models are finally ready for prime time and how Macrocosm is creating tools to simulate economic and energy systems with more nuance, flexibility, and realism than ever before. Dan talks about the interdisciplinary “glory days” of model...
From Chaos to Clarity with Doyne Farmer: Why Agent-Based Models Matter Now 05.05.2025 47:20
On this episode of The Flux, agent-based models (ABMs) have long lived on the fringes of mainstream economics but that’s changing. Doyne Farmer breaks down how advances in computing and data are fueling a new era of bottom-up modeling. He explains where ABMs outperform traditional models, why certain fields (like epidemiology and traffic systems) adopted them earlier, and how economics is finally...
Mining Meaning: Laura Sheppard on Gender, Academia, and the Power of Public Data 22.04.2025 39:40
In this episode of The Flux, we talk with Laura Sheppard, a research fellow at University College London’s Centre for Longitudinal Studies, about how data mining can uncover powerful insights from unexpected sources. Laura shares her work using the British Library’s Ethos dataset, a comprehensive record of UK doctoral theses - to explore gender inequality in higher education. We discuss the proces...
From Micro-Behaviors to Macro-Patterns: Exploring Agent-Based Models with Andrew Crooks 09.04.2025 30:12
In this episode of The Flux , host John Cordier sits down with Andrew Crooks at the Complex Social Systems Society Conference in Santa Fe. They dive into the world of agent-based modeling (ABM) - what it is, why it matters, and how it helps us simulate and better understand human behavior in complex systems. From simulating traffic jams to modeling social influence on vaccine uptake, Andrew shares...
From Neural Networks to Synthetic Populations: Hamdi Kavak’s Journey 17.03.2025 25:59
What if we could predict the impact of a pandemic, a policy change, or even a war before it happens? Hamdi Kavak joins The Flux to discuss how agent-based modeling enables researchers to explore "what if" scenarios and simulate real-world behaviors at both small and massive scales. We dive into the applications of ABM in government-funded projects, the difficulties of modeling millions o...
From Curiosity to Complexity: Paul Amoruso’s Journey into Agent-Based Modeling 04.03.2025 18:39
In this episode of The Flux, host John Cordier, CEO of Epistemix, sits down with Paul Amoruso to explore his unexpected journey into the world of agent-based modeling (ABM). What started as a course recommendation turned into a passion for understanding complex systems and using data to drive better decisions. Paul shares insights from his academic path, the value of interdisciplinary collaboratio...
Complexity in Government Contracting: Jim Malone's Journey into Computational Social Science 19.02.2025 18:21
In this episode of The Flux, host John Cordier interviews Jim Malone at the Complex Social Systems Conference in Santa Fe. Jim, an experienced government acquisition professional, shares his fascinating journey from contracting to pursuing a PhD in Computational Social Science. He discusses the importance of understanding complexity in systems, particularly in government contracting and policy-mak...
Decision-Making in Complex Systems: Insights from Agent-Based Modeling with Aaron Frank 28.01.2025 38:48
Welcome to The Flux! In this episode, host John Cordier, CEO at Epistemix, explores the intricacies of agent-based modeling and its impact on decision-making with Aaron Frank. Recorded live at the Complex Social System Society of America's conference in Santa Fe, New Mexico, Aaron shares his journey from traditional national security research to computational models and agent-based simulation...
Democracy 3.0: Bridging Policy and Technology with Tom Pike 14.01.2025 24:04
In this episode of The Flux, hosted by John Cordier, CEO at Epistemix, we delve into the fascinating world of agent-based modeling (ABM) with Tom Pike, co-lead for MESA. Recorded live at the Complex Systems Society conference in Santa Fe, New Mexico, Tom shares insights on democratizing ABM through Python, its significance in decision-making, and innovative applications such as COVID-19 policy mod...
Randy Burgh: Insights from Economic Development and Complexity Economics 13.01.2025 37:40
This episode explores the economic development potential of technology developed in New Mexico, focusing on industry-based research and the collaboration between companies, universities, and government labs. It delves into the evolution of technology, highlighting key insights from Dr. Brown of the Santa Fe Institute, whose work integrates the concepts of evolutionary technology and complexity eco...
Navigating Complexity: Timothy Clancy on Modeling and Policy-Making 16.12.2024 32:58
In this episode of The Flux, hosted by John Cordier, CEO of Epistemix, we hear from Timothy Clancy, a researcher from the University of Maryland's START program. Recorded at the Complex Social Systems Society of the Americas Conference in Santa Fe, New Mexico, Clancy shares insights from his career, which spans government work and applied studies on national security. They discuss the evoluti...
Exploring Agent-Based Modeling for Complex Policy Challenges with Sherwin Brown 02.12.2024 10:36
In this episode of The Flux, host John Cordier, CEO at Epistemix, interviews Sherwin Brown from MITRE. Sherwin shares his journey into agent-based modeling, starting from his background in health management and policy. He discusses the role of data science and analytics in solving complex problems, such as monitoring the impact of the Affordable Care Act and tackling issues like homelessness and o...
Exploring Data-Driven Decision Making with Bill Rand 18.11.2024 40:22
In this episode of 'The Flux,' we dive deep into data-driven decision making with Bill Rand from NC State University. Join us as Bill discusses his work in agent-based modeling, social media misinformation, and various innovative projects. Discover how agent-based modeling can provide insights into human behavior, business analytics, and even intergenerational trauma. Learn how different...
Revolutionizing Engineering: The Power of AI and Simulation with Dave Freed 04.11.2024 39:32
In this episode of The Flux, join Dave Freed, Senior Director at Ansys, as he delves into the transformative world of computer simulations. With a rich history from Exa Corporation to OnScale and Ansys, Dave explores the evolution and future of simulations, highlighting their pivotal role in automotive, aerospace, and nuclear engineering. Discover how simulations have advanced to replace costly ph...
Transforming Data into Decisions: Insights from Matt Madden at BYU 21.10.2024 44:47
In this episode of The Flux, host John Cordier interviews Matt Madden, Director of the BYU Marketing Lab, about his work in making complex statistics and marketing analytics accessible. Madden discusses the lab's unique approach, which allows students to apply their skills in real-world consulting projects. They delve into key topics like market research techniques such as conjoint analysis,...
Navigating Complex Systems with Don Burke: Epidemiology, AI, and Modeling 07.10.2024 44:31
In this episode of The Flux , host John Cordier sits down with Don Burke, co-founder of Epistemix and a trailblazing epidemiologist, to explore the fascinating intersection of infectious disease research, artificial intelligence, and agent-based modeling (ABM). Burke shares his journey from a traditional career in infectious disease research to becoming a passionate advocate for modeling and simul...
The Tipping Point for Agent-Based Modeling with Rob Axtell 30.09.2024 40:00
In this episode of The Flux, John Cordier interviews Rob Axtell from George Mason University, where he leads the largest graduate program in agent-based modeling (ABM) globally. Axtell shares his journey into complex systems modeling and how the field has evolved since the 1990s. He explains how George Mason’s Ph. D. program in Computational Social Science is shaping the next generation of experts...
The Intersection of Science Fiction and Reality: A Conversation with Sam Arbesman 17.09.2024 37:10
In The Intersection of Science Fiction and Reality episode of The Flux podcast, host John Cordier engages in a conversation with Sam Arbesman, Scientist-in-Residence at Lux Capital and Research Fellow at the Long Now Foundation. They explore how science fiction, video games, and computational social science intersect to influence real-world innovations. Harbisman shares how early experiences like...
The Growing Impact of Agent-Based Modeling with Matt Kohler 03.09.2024 32:21
In this episode of The Flux, John Cordier interviews Matt Kohler, Applied Complexity Scientist at MITRE and President of the Computational Social Science Society of the Americas, about the transformative power of agent-based modeling (ABM). Kohler explains how ABM simulates complex human systems and helps decision-makers understand the ripple effects of their choices. From anthropology to economic...
The Future of Agent-Based Modeling: Insights from Josh Epstein 14.08.2024 39:05
In the inaugural episode of The Flux, John Cordier, CEO of Epistemix, interviews Josh Epstein, Director of the Agent-Based Modeling Lab at NYU and a prominent figure at the Santa Fe Institute. The discussion revolves around the potential and progress of agent-based modeling (ABM), particularly in public health, economics, and beyond. Epstein shares insights into how ABM creates simulations of arti...
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