Brain
The Brain Podcast
A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals. The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists
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Episodes
Distinct brain atrophy patterns in anti-IgLON5 disease 24.06.2026 22:35
Welcome to the 36th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with senior author Dr Carsten Finke of the Brain article entitled: Brain atrophy patterns in anti-IgLON5 disease We discuss a fascinating article which examines clinical and imaging data related to anti-Iglon5 disease. This valuable contri...
Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity 22.04.2026 29:52
Welcome to the 35th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Laetitia Marcadet and senior author Chantelle F Sephton of the Brain article entitled: Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity. We discuss th...
Brain connectivity as a new target for Alzheimer's disease therapy? 18.02.2026 25:20
Welcome to the 34th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Lorenzo Pini of the Brain article entitled: Brain connectivity as a new target for Alzheimer's disease therapy? We discuss a fascinating review into the literature examing brain connectivity in Alzheimer's disease as a...
Models matter: human-specific roles of POU3F2 and Wnt Signalling in neurodevelopment 14.01.2026 27:58
Welcome to the 33rd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Courtney R Benoit and senior author Associate Professor Tracy L Young-Pearse of the Brain article entitled: POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor population We...
Neurotransmitter-informed connectivity maps and predicting stroke functional outcome 26.11.2025 22:11
Welcome to the 32th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Philipp J Koch of the Brain article entitled: Neurotransmitter-informed connectivity maps and their application for outcome inference after stroke We discuss a fascinating method to map neurotransmitter-informed brain...
Do seizures drive the neuropathology of dementia? Insights from a post-mortem study 22.10.2025 22:18
Welcome to the 31th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Ifrah Zawar of the Brain article entitled: The association of seizure control with neuropathology in dementia We discuss an impressive post-mortem investigation of the link between seizures and the associated neuropath...
Investigating autoimmune mechanisms underlying progressive supranuclear palsy 25.09.2025 25:36
Welcome to the 30th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with senior author Professor Gabor G Kovacs of the Brain article entitled: Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy Listen to the fascinating insights exploring the autoimmune sid...
Can transcriptional analysis detect efficient remyelination in multiple sclerosis? 20.08.2025 20:34
Welcome to the 29th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author of the Brain article entitled: Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis We are joined by Alida Chen for an interesting discussion into detecting transcriptional c...
Nephrology Meets Neurology: how kidney health links to neurodegeneration 25.06.2025 36:36
Welcome to the 28th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with three authors of the Brain article entitled: The relationship between kidney health and neurodegenerative diseases Ms Melody Zuo , Dr Le Chang and Professor Sarah A Gagliano Taliun grace the Brain podcast with an insightful discussion...
Understanding traumatic brain injury with high dimensional proteomic analysis 14.05.2025 24:48
Welcome to the 27th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Lucia M Li of the Brain article entitled: High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury Listen to the fascinating insights into classifying traumatic brain injury...
Glymphatic homeostasis in heart failure- more in but not out? 16.04.2025 32:51
Welcome to the 26th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author Dr Marios Kritsilis and senior author Associate Professor Iben Lundgaard of the Brain article entitled: Loss of glymphatic homeostasis in heart failure This academic duo from Lund University discuss their fascinating fin...
Adult congenital myasthenic syndromes - discussing the diagnostic dilemma and other findings from a longitudinal cohort 27.02.2025 21:37
Welcome to the 25th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with senior author Dr Tanya Stojkovic of the Brain article entitled: Congenital myasthenic syndromes in adults: clinical features, diagnosis and long-term prognosis Dr Stojkovic discusses findings from an impressive longitudinal adult cohor...
Nociceptors are functionally male or female: from mouse to monkey to man? 22.01.2025 38:00
Welcome to the first episode of 2025 for The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with senior author Dr Frank Porreca of the Brain article entitled: Nociceptors are functionally male or female: from mouse to monkey to man? Dr Porreca discusses important findings into the sexual dimorphic nature of nociception...
Academic neurology in the UK: a plea to turn away from the precipice 11.12.2024 28:59
Welcome to the 23nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . In this episode, we bring on authors Dr Helen Devine and Professor Simon Mead to discuss their opinion article entitled: Academic neurology in the UK: a plea to turn away from the precipice. The discussions covers the growing concerns regarding the future of academic neurolog...
Can Epilepsy surgery improve or even reverse cognitive deficits in children with epilepsy? 16.10.2024 27:52
Welcome to the 22nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with senior author Dr Torsten Baldeweg of the Brain article entitled: Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline? Dr Baldeweg discusses fascinating insight into the long term cognitive outc...
Anti-IgLon5 disease risk is mediated by HLA-DQB1*05 subtypes: when neuroimmunology meets neurodegeneration 14.08.2024 34:26
Welcome to the 21th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with the first author Dr Selina Yogeshwar of the Brain article entitled: HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease Dr Yogeshwar offers exciting insight into the genetic mechanisms of a relatively recently...
The essential Role of PAK2 in Myelinating the Peripheral Nervous System 20.06.2024 25:44
Welcome to the 20th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with the final author Dr Jun Li of the Brain article entitled: PAK2 is necessary for myelination in the peripheral nervous system How are peripheral nerve cells myelinated and what proteins are invoved? Is there a difference between PAK1 and...
How is the gut microbiota related to cognition and hippocampal neurogenesis in Alzheimer's disease? 15.05.2024 29:18
Welcome to the 18th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with first author author Dr Stefanie Grabrucker of the Brain article entitled: Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis How does lifestyle and the environment affect cognition in Alzheime...
Do noradrenergic alterations in Parkinson's disease indicate a therapeutic target? A combined PET & neuromelanin MRI study 03.04.2024 22:38
Welcome to the 17th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . This episode features a discussion with senior author Dr Bénédicte Ballanger of the Brain article entitled: Noradrenergic alterations in Parkinson's disease: a combined 11 C-yohimbine PET/neuromelanin MRI study Can this multi-modal study examining the role of Noradrenaline i...
Altered brain glucose metabolism as a mechanism for delirium? 14.02.2024 16:08
Welcome to the 16th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . We are very excited to feature a January issue Brain article, where we speak with senior author Dr Lasse M Giil entitled: Impaired glucose utilization in the brain of patients with delirium following hip fracture Delirium is a common condition with significant impact on pat...
Are there differences in the immune response among individuals of Black ethnicity with multiple sclerosis? 15.11.2023 19:35
Welcome to the 15th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . We are very excited to feature our first article from Brain Communications, where we speak with first author Dr Kiel Telesford of the article entitled: Neuron-binding antibody responses are associated with Black ethnicity in multiple sclerosis during natalizumab treatment Thi...
Exploring a genetic basis for disordered speech and language: FOXP2 mutations and striatal neurons 11.10.2023 20:12
Welcome to the 14th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . In this episode we speak with Fu-Chin Liu, senior author of the article entitled: Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons. This article explores a potential genetic basis for disordered speech by a mutation in the transcription...
Multisite thalamic recordings to characterize seizure propagation in the human brain 13.09.2023 28:29
Welcome to the 13th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . In this episode we speak with Josef Parvizi, senior author of the article entitled: Multisite thalamic recordings to characterize seizure propagation in the human brain This article explores the role of the thalamus in seizure propagation and how multi-site intracranial elect...
A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies 14.08.2023 16:25
Welcome to the 12th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . In this episode we speak with Nico Melzer, senior author of the article entitled: A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies This article explores expanding entity of GAD-65 associated neurological syndromes, the excit...
RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain 05.07.2023 26:42
Welcome to the 11th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications . In this episode we speak with Ted Price, senior author of the article entitled: RNA profiling of human dorsal root ganglia (DRG) reveals sex differences in mechanisms promoting neuropathic pain This article explores exciting findings around differences in the DRG transcriptom...
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