The AI in Business Podcast

Enterprise AI initiatives treat design as a finishing step. Carsten Wierwille, Chief Product & Design Officer at HTEC, argues that this is a strategic mistake, and one that explains why so many AI investments produce tools that work technically but fail to change how people actually work. In this episode, Wierwille examines why enterprises keep building AI because they can rather than because they...

Computer vision implementations in manufacturing never advance beyond the pilot phase — not because the technology fails, but because deployment is treated as a software problem rather than an operational one. In this episode, Jeff Witt, Digital Transformation Leader at a Fortune 500 global leader in building materials and fiberglass composites, examines the architectural, organizational, and chan...

The growing use of AI‑driven modeling in clinical development is exposing how limited traditional, single‑study dose selection and patient assessment methods have been for complex oncology programs. In this episode, Shefali Kakar, Global Head of PK Sciences and Oncology at Novartis, examines how deeper data integration across phases enables more precise dose decisions, clearer safety interpretatio...

The pressure on financial services AI leaders to show board-level results has intensified — yet the pace of vendor pitches, shifting tooling stacks, and stalled pilots has made action feel riskier than waiting. In this episode, Art Shectman, CEO and Founder at Elephant Ventures, breaks down why the instinct to evaluate everything before building anything is the primary obstacle to production, and...

The reason enterprise AI programmes stall is not the technology — it is the sequence in which decisions are made before and after the pilot succeeds. In this episode, Ronny Fehling, Chief AI Transformation Officer at HTEC, examines why AI initiatives lose momentum at the production threshold and what organisational conditions determine whether they make it through. The discussion covers production...

Deepfake voice fraud is not bypassing enterprise security technology, it is beating the workflows agents rely on to make trust decisions in real time. In this episode, Jon-Rav Shende, Global CTO for Data and AI at Thales Group, outlines where enterprise voice channels are most exposed, why identity, urgency, and business action converging in a single call represents the highest risk point, and wha...

A growing share of pharmaceutical innovation is now constrained not by scientific imagination, but by the infrastructure required to support AI at scale. In this episode of the AI in Business podcast, Thomas Fuchs, Chief AI Officer at Eli Lilly & Company, joins Matthew DeMello to explore how Lilly's new AI supercomputing platform is reshaping scientific discovery and enterprise operations. The con...

Boards are pushing CIOs to commit to AI strategies built on contracts written for an entirely different era of enterprise software. In this episode, John Belden, Chief of Research and Strategy at UpperEdge, breaks down the six dimensions of uncertainty CIOs now face when weighing major AI and ERP commitments, and explains why the next five years are about flexibility, not productivity. The convers...

Context defines accurate, reliable AI decision‑making, forcing enterprises to confront the fragmentation that prevents systems from accessing the information those decisions depend on. In this episode, Ravi Marwaha, Chief Operating Officer & Chief Technology Product Officer at Arango, examines how AI breaks down when it is asked to reason across disconnected architectures that cannot supply a unif...

A significant share of manufacturing knowledge still lives in the heads of retiring workers, and the window to capture it is closing as operations push toward AI-enabled ways of working. In this episode, Anand Gnanamoorthy, Director of Corporate Strategy and AI at Ingersoll Rand, examines how manufacturers can digitize tribal knowledge, structured operational data, and decades of unstructured arch...

Enterprise service leaders are realizing that deploying AI for simple productivity gains fails to resolve the underlying issues that cause repeat truck rolls and high costs. In this episode, Niken Patel, CEO and Co-Founder at Neuron7.ai, unpacks why moving beyond basic automation requires a deterministic intelligence layer to make fragmented data ready for complex resolution decision-making. The d...

Energy organizations have made progress in safety, but most still rely on backward‑looking investigations rather than systems that anticipate when risk is rising. In this episode, Patricio Rivera, Former Vice President of HSE International at Oxy, joins host Matthew DeMello and examines how learning from good days and leveraging existing observation data can strengthen an organization's ability to...

AI enthusiasm has outpaced enterprise readiness, leaving many organizations stuck with pilots that work in the lab but fail to deliver meaningful value in production. In this episode, Lawrence Whittle, Chief Strategy Officer at HTEC Group, joins Emerj's Marilie Fouché to examine how the gap between individual users, isolated use cases, and true end‑to‑end sequences prevents companies from moving b...

Agentic AI is running into a hard limit: most enterprise systems, security layers, and operational backends aren't yet built to support automated execution at scale.  Alex Tyrrel, SVP and CTO of Health at Wolters Kluwer, joins Emerj's Matthe DeMello to unpack how agentic systems adapt models to domain‑specific tasks and act directly inside regulated environments. He outlines the practical requirem...

A widening gap between retiring experts, manual craftsmanship, and limited process visibility is making it increasingly difficult for manufacturers to maintain consistency, prevent errors early, and onboard new operators effectively. In this episode, Sebastian Dykas, Director of Manufacturing, Engineering, and Maintenance at Smith+Nephew, joins Emerj's Marilie Fouche to examine how capturing best...

Volatility is exposing the limits of traditional scenario planning, where siloed KPIs and thin operational margins prevent enterprises from seeing how disruptions cascade across forecasting, procurement, and operations. In this episode, Dr. Gopalendu Pal, Director of Operations at Target, joins us to examine how running hundreds of interconnected simulations enables leaders to understand enterpris...

Voice-based fraud has moved from a fringe security concern to a primary operational risk for financial institutions and enterprise contact centers, and the authentication methods most organizations rely on are no longer adequate. In this episode, Ken Morino, Director of Market and Behavioral Research at Modulate, examines how enterprise leaders can deploy real-time voice intelligence to detect fra...

The consistency gap in enterprise AI represents a critical failure point where unpredictable system behavior outside of controlled demos threatens to derail executive sponsorship and regulatory compliance. In this episode, Amar Akshat, SVP & Chief Architect at Paysafe, examines how leaders can move beyond experimental shadow AI by embedding determinism and high-threshold guardrails directly into t...

Legacy financial systems often trap organizations in "data swamps" where AI is mistakenly treated as a magic fix for fundamentally broken manual architectures. In this episode, Juan Orlandini, CTO of North America at Insight, outlines why senior executives must distinguish between statistical AI outputs and the mathematical precision required for financial compliance to avoid significant reporting...

R&D teams are starting to advance AI capabilities faster than they can translate them into measurable business value, creating mounting friction between scientific progress and operational reality. In this episode, Aziz Nazha, Global Head of AI Innovations Institute at Incyte Pharmaceuticals, examines how culture, talent, infrastructure, and expectation‑setting determine whether AI meaningfully im...

A recurring challenge for leaders is that the use cases they expect to automate rarely match what customers actually struggle with once large‑scale conversation data is analyzed. In this episode, Shezan Kazi, Head of AI Transformation and AI Products at Dialpad, examines how autonomous agents should take the first pass on high‑volume deterministic requests, when they must hand off to humans, and w...

A major shift is underway as enterprises move from lab‑ready computer vision to the far more complex reality of deploying visual intelligence across messy, variable, high‑stakes physical environments. In this episode, Joseph Nelson, Co‑founder and CEO at Roboflow, examines how dependable visual data, models tuned to real operating conditions, and integration with existing production and safety sys...

Today's guest is Aaron Demory, Senior Partner at Fearlus and Chief of Information Technology and Security at the FDIC. Fearlus is a strategic governance and risk innovation firm headquartered in Washington, D.C., founded in 2024. They offer the Fearlus Risk Operating Model, a structured approach designed to help organizations align strategy, execution, and governance through cognitive infrastructu...

Operational complexity in modern distribution centers is accelerating faster than most organizations can adapt, leaving leaders with fragmented data, static facility designs, and inefficiencies that compound across planning and fulfillment. In this episode, Jerod Hamilton, Director of 3PL Warehouse Strategy at Tyson Foods, joins Emerj's Marilie Fouche to examine how disconnected forecasting and wa...

Today's guest is Emma Vitalini, Head of Global Digital Health Technology Innovation at Amgen. Amgen is a global biotechnology company focused on discovering, developing, and delivering medicines for serious illnesses. Emma joins Emerj Editorial Director Matthew DeMello to examine how data and AI are reshaping patient recruitment, decentralized clinical trials, and compliance workflows in highly re...