Andreessen Horowitz

The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Author

Andreessen Horowitz

Category

Technology

Podcast website

a16z.simplecast.com

Latest episode

Jul 10, 2026

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Episodes

16 Minutes on the News #7: Apple Card, BEC Scams Federal Indictment 25.08.2019

with @illscience and @smc90 This is episode #7 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends. This week we cover, with the following a16z experts: Apple releasing a credit card, and what it means beyond the card features itself...

a16z Podcast: Software has eaten the world...and healthcare is next 15.08.2019

Back in 2011, a16z cofounder Marc Andreessen first made the bold claim that software would eat the world. In this episode (originally recorded as part of an event at a16z), Andreesseen and a16z general partner on the bio fund Jorge Conde (@JorgeCondeBio) take a look back at that thesis, and think about where we are now, nearly a decade later—how software has delivered on that promise… and most of...

16 Minutes on the News #6: Health Claims, Corporate Breaches 12.08.2019

with @julesyoo @smc90 This is episode #6 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we cover, with the following a16z experts: health claims, insurance & big tech, and healthcare data liquidity -- with...

16 Minutes on the News #5: Fed Real-time Payments, Death of Retail 11.08.2019

with @astrange @jeff_jordan and @smc90 This is episode #5 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we cover, with the following a16z experts: Federal Reserve real-time payment and settlement service FedNo...

16 Minutes on the News: The Opioid Crisis 04.08.2019

with @jorgecondebio @vijaypande and @smc90 This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we do a short but deep dive on the opioid crisis, given recent data around where and who was behind t...

16 Minutes on the News: Fortnite, Esports, Gaming, and Entertainment 04.08.2019

with @andrewchen @dcoolican and @smc90 This is episode #3 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we do a short but deep dive on esports, given recent news of the inaugural Fortnite World Cup champion, a...

16 Minutes on the News: Mobile Malware, Drug Pricing 28.07.2019

with @martin_casado @jorgeconde @jayrughani and @smc90 This is episode #2 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we cover, with the following a16z experts: . mobile malware and a recent report of a new...

a16z Podcast: The Search for the Secret Metal that Powers All Our Devices 23.07.2019

with Kurt House (@kurtzhouse), John Thompson, Connie Chan (@conniechan) and Hanne Tidnam (@omnivorousread) The exploration for and mining of certain metals has driven huge epochs of human civilization, from copper and iron to gold and diamonds. In this conversation, Kurt House, CEO and co-founder of KoBold Metals; John Thompson, professor of earth and geosciences at Cornell and longtime advisor to...

16 Minutes on the News: Neuralink & Brain Interfaces, TikTok, FaceApp, iHeartRadio 21.07.2019

with @vijaypande @conniechan @jpm25 and @smc90 Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? This is the first episode of the show, and this week we cover the below topics with...

a16z Podcast: How To Get The Most From Your Board 19.07.2019

In this final of a 3-part series (which originally aired as YouTube videos) on working with venture investors, a16z Managing Partner Scott Kupor shares best practices for working with your board as it grows from just you, your co-founders and first investor all the way through the time when you are recruiting independent board members in preparation for going public. Want to learn more? Read Scott...

a16z Podcast: How To Raise Money From A Venture Investor 18.07.2019

So you've decided raising venture capital is the best fundraising strategy for your startup. Now what? In this second of a 3-part series, a16z Managing Partner Scott Kupor shares actionable fundraising advice based on his experience of seeing thousands of startup pitches and working on all of a16z's investments. Want to learn more? Read Scott's book "Secrets of Sand Hill Road: Venture Capital...

a16z Podcast: How To Understand And Choose A Venture Investor 17.07.2019

Incentives matter. So understanding the incentives of venture capitalists will help you decide if raising money from a venture investor makes sense for your business. In this first of a 3-part series, which originally aired as YouTube videos, a16z Managing Partner Scott Kupor talks with Frank Chen about how venture capital works: how the money flows, what Limited Partners (the organizations that i...

a16z Podcast: Beyond Software, to Talent and Culture 04.07.2019

with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen) Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2018 at our annual innovation Summit, and fe...

a16z Podcast: Beyond Zero Sum, Again 04.07.2019

with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson) Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2017 at our annual innovation Summit,...

a16z Podcast: Beyond Software Eating the World 04.07.2019

with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2016 -- on the 5-year an...

a16z Podcast: Beyond Disruption Theory 04.07.2019

with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Michael Copeland Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2014, on the 5-year anniversary of the firm, and feat...

a16z Podcast: Entrepreneurs, Then and Now 28.06.2019

with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Stewart Butterfield (@stewart) A lot in technology -- and venture -- happens in decades. New cycles of technology come and go, including some secular shifts; a new generation of founders matures; and so much more changes. So when Andreessen Horowitz (dubbed with the numeronym "a16z") was founded a decade ago as of this month,...

a16z Podcast: Damage-free Genome Editing -- Next in CRISPR 26.06.2019

Two recent scientific journal papers show what's possible when CRISPR moves from cutting DNA tool to a full-fledged platform -- expanding its toolkit for medicine across R&D, therapeutics, and diagnostics: "Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration" in Nature -- by Sanne Klompe, Phuc Vo, Tyler Halpin-Healy, and Samuel Sternberg (of Columbia University) &...

a16z Podcast: Stories from the Frontlines of Synthetic Fraud 25.06.2019

Synthetic fraud—yes, it's a thing: a new evolution of consumer fraud that’s been emerging in financial services, to the tune of $1-$2B a year. In this episode of the a16z Podcast, Naftali Harris, co-founder and CEO of Sentilink, which builds technology to detect and stop synthetic fraud, talks with a16z's Hanne Tidnam and operating partner for information security Joel de la Garza all about what t...

a16z Podcast: The History and Future of Machine Learning 19.06.2019

How have we gotten to where were are with machine learning? Where are we going? a16z Operating Partner Frank Chen and Carnegie Mellon professor Tom Mitchell first stroll down memory lane, visiting the major landmarks: the symbolic approach of the 1970s, the "principled probabalistic methods" of the 1980s, and today's deep learning phase. Then they go on to explore the frontiers of resear...

a16z Podcast: The Politics of Technology 15.06.2019

with Tony Blair (@InstituteGC), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) If the current pace of tech change is the 21st-century equivalent of the 19th-century Industrial Revolution — with its tremendous economic growth and lifestyle change — it means that even though it’s fundamentally empowering and enabling, there’s also lots of fears and misconceptions as well. That’s why, argues forme...

a16z Podcast: AI and Your Doctor, Today and Tomorrow 13.06.2019

with Eric Topol (@EricTopol) and Vijay Pande (@vijaypande) Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol, cardiologist and chair of innovative medicine at Scripps Research, and a16z’s general partner on the Bio Fund Vijay Pande, have a conversation around Topol’s new book, Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. What i...

a16z Podcast: 10+1 Lessons from Serial Entrepreneur Justin Kan 10.06.2019

Want actionable advice from a founder who has built multiple tech companies and has invested the time to be open, introspective, and transparent about lessons learned? In this episode (which originally aired as a YouTube video), a16z General Partner Andrew Chen (@@andrewchen) talks with Justin Kan (@justinkan). Justin is a repeat entrepreneur who co-founded Kiko Software (a Web 2.0 calendar that p...

a16z Podcast: Deep Learning for the Life Sciences 06.06.2019

with Vijay Pande (@vijaypande) and Bharath Ramsundar Deep learning has arrived in the life sciences: every week, it seems, a new published study comes out... with code on top. In this episode, a16z General Partner Vijay Pande and Bharath Ramsundar talk about how AI/ML is unlocking the field in a new way, in a conversation around their book, Deep Learning for the Life Sciences: Applying Deep Learni...

a16z Podcast: The Power of Restorative Justice 03.06.2019

with Van Jones (@VanJones68), Shaka Senghor (@ShakaSeghnor), and Chris Lyons (@clyons) True redemption can be hard to come by in our justice system today. And yet, we need it more than ever before. In this episode (based on an event hosted by Andreessen Horowitz's Cultural Leadership Fund), CNN news commentator and author Van Jones and Shaka Senghor, author of the New York Times bestseller Writing...

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