Retina Synthesis

Retina Synthesis

Retina Synthesis is a data-focused resource exploring therapies in development for retinal diseases.

Author

Retina Synthesis

Category

Education

Podcast website

retinasynthesis.com

Latest episode

Jul 7, 2026

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Episodes

Optogenetics for Treating Inherited Retinal Degenerations 11.12.2025

We discuss promising Phase 2 results from Nanoscope regarding the use of optogenetics for treatment of retinal degenerations with Allen Ho, MD, Professor of Ophthalmology, Wills Eye Hospital.

Untitled EpisodeArtificial Intelligence in the Management of Macular Disease 03.12.2025

We discuss the early results of the use of artificial intelligence in the management of macular disorders with Dr. Pearse Keane, the world's first Professor of Artificial Medical Intelligence, University College London, Moorfields Eye Hospital.

Stem Cell Therapy for Geographic Atrophy 19.11.2025

We discuss with Dr. Rajesh C. Rao, Leonard Miller Professor of Ophthalmology, Kellogg Eye Center, University of Michigan, the results of a Phase I trial exploring the use of stem cells injected subretinally in eyes with geographic atrophy. The results are promising.

Intravitreal Gene Therapy for Neovascular AMD 13.11.2025

We discuss  the early results of gene therapy of neovascular AMD by intravitreal administration of the vector with Dr. Glenn Yiu, Professor of Ophthalmology, University of California, Davis.

The TRUCKEE Study of Faricimab for Neovascular AMD 05.11.2025

We discuss the long term results of the Truckee Study, a stage 4 clinical trial in the treatment of neovascular AMD with faricimab with Dr. Arshad Khanani from Sierra Eye Associates, Reno, Nevada.

The VERONA Trial of a TKI for the Treatment of DME 29.10.2025

We discuss the use of a tyrosinase kinase inhibitor, EY-1901, for the treatment of diabetic macular edema with Dr. Yasha Modi, New York University, and Manhattan Eye Ear and Throat Hospital, New York.

Photobiomodulation for the Treatment of Dry AMD 24.10.2025

We discuss early results from the study of photobiomodulation for the treatment of dry AMD with Dr. David Boyer, Adjunct Professor of Clinical Ophthalmology,  Keck School of Medicine of USC, Roski Eye Institute.

8 mg Aflibercept in Diabetic Macular Edema 08.10.2025

We review long term results from the PHOTON Study with Eric Schneider, MD, Tennessee Retina, Nashville, TM.

Subretinal Gene Therapy for Neovascular AMD 03.10.2025

We review the latest results from the Regenexbio sub retinal gene therapy program with Robert Avery MD, California Retina Consultants, Santa Barbara, CA

Does Pegcetacoplan Treatment Affect Dry Macular Degeneration? 25.09.2025

We discuss whether pegcetacoplan therapy of geography atrophy affects the progression of dry AMD with Paul Hahn MD PhD of PH Retina, Nanuet, New York.

Rapid Fluid Resolution with Aflibercept 8mg may be Associated with Extended Dosing Intervals in nAMD 08.09.2025

We discuss the observation that resolution of retinal fluid at one month in eyes with nAMD treated with aflibercept 8mg may herald longer duration treatment intervals at week 96 with Michael Stewart,, MD, Knights Templar Professor of Ophthalmology, Mayo Clinic, Jacksonville, Florida.

The Good Days Dilemma - Support for Patient Co-Payments in Retinal Pharmacotherapy 28.08.2025

We discuss the current state of the Good Days charitable foundation with Dr. Michael Lai, MD. PhD, Retina Group of Washington, Assistant Clinical Professor, Georgetown University School of Medicine

Immediate vs Delayed Treatment of GA with Pegcetacoplan 19.08.2025

We discuss the long term results of the Oaks, Derby, and GALE studies looking at the benefit of early treatment of geographic atrophy in AMD with Dr. Roger Goldberg of Walnut Creek, California.

Eyes with both Geographic Atrophy and Neovascular AMD: An IRIS Study 12.07.2024

We discuss management of eyes with both geographic atrophy and neovascular AMD with Dr. Ted Leng of the Byers Eye Institute, Stanford University School of Medicine

The Davio 2 Trial for Neovascular AMD 31.05.2024

We review the 6 month results of the Davio 2 trial of  the Durayvu TKI delivery system for maintenance therapy of neovascular AMD with Dr. Carl Regillo of Wills Eye Hospital.

The GALE Extension Study 17.05.2024

We discuss the latest promising results from the GALE extension study of pegcetacoplan with Dr. Ashkan Abbey of Texas Retina Associates

AXPAXLI for Diabetic Retinopathy 09.05.2024

We discuss the promising phase I results of the Helios trial studying AXPAXLI  TKI inhibitor implant for diabetic retinopathy with Dr. Dilsher Dhoot of California Retina Consultants.

NSAIDS in the treatment of Central Serous Chorioretinopathy 18.04.2024

We discuss the use of non steroidal inflammatory agents in the management of central serous chorioretinopathy  with Dr. Michael Singer of San Antonio, Texas

EY-103 a novel Wnt Pathway Agonist for Treatment of DME and neovascular AMD 04.04.2024

We discuss remarkable preliminary results from the the use of intravitreal EYE-103, a novel Wnt pathway agonist in the treatment of DME and neovascular AMD with Dr. Charles Wykoff of Houston Texas.

Intravitreal Gene Therapy for neovascular AMD with 4D-150 28.03.2024

We discuss the first interim results of a novel intravitreal gene therapy agent, 4D-150, with Dr. Arshad Khanani of Sierra Eye Associates and the University of Nevada Reno School of Medicine.

KSI 501 Bispecific Anti-VEGF Biopolymer Treatment of DME 21.03.2024

We discuss the use of a novel bispecific anti-VEGF Anti IL-6 Antibody Biopolymar Conjugate for the treatment of DME with Dr. Mark R. Barakat of Phoenix, AZ.

Retinal Vasculitis Following Pegcetcoplan Therapy of Geographic Atrophy 14.03.2024

We discuss the occurrence of retinal vasculitis following pegcetcoplan therapy of geographic atrophy with Dr. Andrew Witkin of the New England Eye Center, Tufts University School of Medicine

High Dose Aflibercept in Severe Diabetic Macular Edema 07.03.2024

We discuss the treatment results of high dose aflibercept in the eyes in the most severe quartile of diabetic macular edema with Dr. Roger Goldberg of Walnut Creek, California.

IL-6 Inhibition in the Treatment of Uveitis Macular Edema 29.02.2024

We discuss the use of an IL-6 inhibitor in the treatment of uveitis macular edema with Dr. Sumit Sharma of the Cole Eye Institute, Cleveland Clinic.

The High Dose Aflibercept DME Trial 22.02.2024

We discuss the baseline characteristics of eyes in the HD Aflibercept Phase III clinical trial and examine their ability for extended dosing with Dr. Eric Schneider of Tennessee Retina, Nashville, TN.

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