Research To Practice | Oncology Videos

Featuring a slide presentation and related discussion from Dr Ezra Cohen, including the following topics: Current standard therapy for head and neck cancer (0:00) Emerging data from clinical trials in head and neck cancer (3:41) Current standard therapy and recent research data in thyroid cancer (15:35) CME information and select publications

Featuring perspectives from Dr Daniel DeAngelo, including the following topics: Introduction: Perspectives on chronic myeloid leukemia (CML) (0:00) Asciminib — ASC4FIRST study (8:33) Case: A woman in her early 60s with a PMH of Stage IA hormone receptor-positive breast cancer on adjuvant tamoxifen with newly diagnosed CML — Michael R Grunwald, MD (22:38) Case: A man in his mid 40s with low-risk CM...

Featuring perspectives from Dr Ursula Matulonis, including the following topics: Introduction: Journal Club with Ursula Matulonis, MD — Part 1 (0:00) Case: A woman in her late 60s with primary peritoneal carcinoma with a germline BRCA mutation who underwent naturopathic therapy — Dana M Chase, MD (31:08) Case: A woman in her late 70s with Stage IIIC fallopian tube cancer (homologous recombination...

Efficacy data with T-DXd from the DESTINY-Breast04 trial for patients with HER2-low breast cancer; incidence and biologic relevance of HER2 mutations in breast cancer (0:00) Current and potential clinical roles for liquid biopsy in breast cancer; cardiac toxicity with T-DXd in the DESTINY-Breast04 trial (6:10) Safety profile of T-DXd from the DESTINY-Breast04 trial (11:09) Incidence and management...

Featuring a slide presentation and related discussion from Dr Shanu Modi, incluing the following topics: Biology and incidence of HER2-low breast cancer (0:00) Emerging clinical trial data with targeted therapies for HER2-low breast cancer (4:53) Future directions in the treatment of HER2-low breast cancer (16:58) CME information and select publications

Featuring an interview with Drs Jeffrey Bradley and David Spigel, including the following topics: Clinical Investigator Perspectives on the Management of Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC) (0:00) Multimodality Management Options for Patients with Unresectable Stage III NSCLC — Jeffrey Bradley, MD (35:46) Integration of Immune Checkpoint Inhibition into the Management of Unre...

Featuring perspectives from Prof Ghassan Abou-Alfa, including the following topics: Introduction (0:00) Case: A woman in her early 50s with metastatic hepatoid carcinoma of the ovary with an FGFR fusion — Syed M Ahmed, MD, PhD (2:56) Key recent data sets (5:59) Case: A man in his mid 60s with a history of Child-Pugh B cirrhosis and Grade 1 esophageal varices who is receiving atezolizumab/bevacizum...

Featuring a slide presentation and related discussion from Dr Sandy Srinivas, including the following topics: Results from the Phase II SALV-ENZA trial evaluating salvage radiation therapy with enzalutamide or placebo for high-risk PSA-recurrent prostate cancer after radical prostatectomy (0:00) Updated overall survival outcomes from the ENZAMET trial of enzalutamide for metastatic hormone-sensiti...

Featuring an interview with Dr Sandy Srinivas, including the following topics: Rationale for and efficacy data from the Phase II SALV-ENZA trial of salvage radiation therapy with enzalutamide or placebo for high-risk recurrent hormone-sensitive prostate cancer (0:00) Results from clinical trials evaluating abiraterone, docetaxel or apalutamide for patients with hormone-sensitive prostate cancer (3...

Featuring perspectives from Dr Richard Stone, including the following topics: Introduction: RATIFY trial in perspective (0:00) Treatment with FLT3 inhibitors (7:00) Anti-CD47 antibody: Magrolimab (23:04) Anti-TIM-3 antibody: Sabatolimab (31:23) CAR T-cell therapy for acute myeloid leukemia (34:53) Targeted therapy with IDH inhibitors (37:31) New myelodysplastic syndromes classification system (41:...

Featuring perspectives from Dr Christopher Flowers and Ms Robin Klebig, including the following topics: Management of Diffuse Large B-Cell Lymphoma (0:00) Caring for Patients with Hodgkin Lymphoma (32:59) Treatment for Follicular Lymphoma (44:17) Managing Mantle Cell Lymphoma (58:12) NCPD information and select publications

Featuring an interview with Professor Juan Valle, including the following topics: Immunotherapy for patients with biliary tract cancers (BTCs) (0:00) Etiology and presentation of and recent advances in the management of cholangiocarcinoma (4:18) Targeting FGFR alterations in cholangiocarcinoma and other BTCs (12:47) Spectrum and management of toxicities associated with FGFR inhibitors (19:33) Targ...

Featuring a slide presentation and related discussion from Professor Juan Valle, including the following topics: Management of biliary tract cancers (BTCs) with targetable mutations (0:00) Management of BTCs without targetable mutations (13:59) Novel targets and treatments for cholangiocarcinoma and other BTCs (20:19) CME information and select publications

Featuring perspectives from Dr Jorge Cortes, including the following topics: Introduction: Journal Club with Dr Cortes (0:00) Case: A man in his early 40s with chronic myeloid leukemia (CML) and osteopenia after long-term imatinib therapy — Rajalaxmi McKenna, MD (15:00) Case: A man in his early 60s with chronic phase CML (CP-CML) and continued detectable BCR-ABL transcript on bosutinib — Bruce Ban...

Featuring perspectives from Dr Joel Neal, including the following topics: Introduction: Journal Club with Joel W Neal, MD, PhD (0:00) Case: A woman in her mid 60s with Stage I NSCLC with an EGFR mutation and emphysema — Joanna Metzner-Sadurski, MD (18:00) Case: A woman in her late 60s with localized papillary NSCLC with an EGFR L864Q mutation — William R Mitchell, MD (20:42) Case: A woman in her e...

Featuring a slide presentation and related discussion from Dr Angela DeMichele, including the following topics: HER2 and HER3-directed therapies for locally advanced and metastatic breast cancer (0:00) Immunotherapies and antibody-drug conjugates for triple-negative breast cancer and genetic alterations associated with response (13:14) Targeted therapies for estrogen receptor-positive, HER2-negati...

Featuring an interview with Dr Angela DeMichele, including the following topics: Staining for HER2 expression and clinical relevance of HER2-0 breast cancer (0:00) Biology of HER2-mutated breast cancer; sequencing of sacituzumab govitecan and trastuzumab deruxtecan for estrogen receptor (ER)-negative breast cancer (4:21) Role of trastuzumab deruxtecan in HER2-low, ER-positive breast cancer; biolog...

Featuring perspectives from Dr Jeff Sharman, including the following topics: Introduction (0:00) Case: A man in his late 50s with progressive small lymphocytic lymphoma who developed acalabrutinib-associated rash — Shams Bufalino, MD (22:14) Case: A man in his late 60s with recurrent deep-vein thrombosis who is receiving warfarin and is diagnosed with chronic lymphocytic leukemia (CLL) requiring t...

PARP Inhibition in the Management of Prostate Cancer — Where We Are and Where We're Headed — Faculty Presentation 2: Available Data with, Ongoing Investigation of and Potential Future Role of PARP Inhibitor-Based Combination Strategies — Dr Fred Saad CME information and select publications

PARP Inhibition in the Management of Prostate Cancer — Where We Are and Where We're Headed — Faculty Presentation 1: Optimal Integration of PARP Inhibitor Monotherapy into the Management of Metastatic Castration-Resistant Prostate Cancer — Prof Johann de Bono CME information and select publications

Featuring perspectives from Dr Shannon Westin, including the following topics: Introduction (0:00) Case: A woman in her late 50s with Stage IIIC high-grade serous carcinoma with a gBRCA2 mutation — Gigi Chen, MD (19:58) Case: A woman in her mid 60s with Stage IIA BRCA1/2 wild-type, high-grade serous ovarian adenocarcinoma — Syed M Ahmed, MD, PhD (23:16) Case: A woman in her early 60s with metastat...

Featuring perspectives from Dr Melissa Johnson, including the following topics: Introduction: KRAS in Lung Cancer (0:00) Case: A woman in her early 60s with adenocarcinoma of the lung and a ROS1 fusion, with bone, brain and leptomeningeal metastases — Gigi Chen, MD (15:52) Case: A man in his late 50s with Stage IVa lung cancer and malignant pleural effusion and a BRAF V600E mutation (PD-L1 60%) —...

Featuring perspectives from Drs Ajai Chari, Elizabeth O'Donnell and Robert Orlowski, including the following topics: Introduction (0:00) Front-Line and Maintenance Treatment Options for Patients with Multiple Myeloma (MM) (2:03) Selection and Sequencing of Therapy for Patients with Relapsed/Refractory MM (28:22) Future Directions in the Management of MM (36:31) CME information and select publicati...

Featuring perspectives from Prof Eric Van Cutsem, including the following topics: Introduction: Journal Club with Prof Van Cutsem (0:00) Case: A woman in her mid 70s with HER2-negative metastatic gastric cancer (MSI high, PD-L1 >20%) — Nemrata I Peswani, MD (16:51) Case: A man in his mid 70s with multiple comorbidities and HER2-negative metastatic gastroesophageal junction (GEJ) adenocarcinoma (MS...