Research To Practice | Oncology Videos

Featuring an interview with Dr Charles Powell, including the following topics: Role of the pulmonologist in the cancer care team; frequency of fatal and Grade 4 interstitial lung disease (ILD) with antibody-drug conjugates (0:00) Pathophysiology of pneumonitis associated with checkpoint inhibitors versus antibody-drug conjugates; differences in presentation of ILD based on the cause of disease (8:...

Featuring perspectives from Dr Jacob Sands, including the following topics: Introduction: Journal Club (0:00) Case: A woman in her mid 50s with extensive-stage small cell lung cancer (ES-SCLC) who had an excellent response to chemotherapy with immunotherapy (IO) and has been on maintenance IO for 2 years — Adam R Miller, MD (22:05) Case: A woman in her mid 60s with ES-SCLC who presented with super...

Featuring a slide presentation and related discussion from Dr Mansoor Raza Mirza, including the following topics: Molecular classification of endometrial cancer and immunotherapy options for patients with microsatellite instabiliity-high/DNA mismatch repair deficient endometrial cancer (0:00) Immunotherapy for mismatch repair-proficient endometrial cancer (9:18) Ongoing Phase III trials evaluating...

Featuring an interview with Dr Mansoor Raza Mirza, including the following topics: Delivery of care models for endometrial cancer (0:00) Molecular profiling and treatment for endometrial cancer (1:57) Current use of immunotherapy for the management of endometrial cancer (8:56) Mitigating and managing immunotherapy-associated adverse events for patients with endometrial cancer (13:40) Immune checkp...

Featuring perspectives from Dr John Strickler, including the following topics: Introduction (0:00) Case: A man in his early 60s with gastroesophageal junction (GEJ) adenocarcinoma who responds to neoadjuvant chemoradiation therapy but declines surgery and develops progressive disease (HER2 1+, PD-L1 2%) — Minesh Dinubhai Patel, MD (13:54) Case: A frail woman in her late 80s with unresectable gastr...

Featuring a slide presentation and related discussion from Dr Asim Farooq, including the following topics: Molecular classification of endometrial cancer and immunotherapy options for patients with microsatellite instabiliity-high/DNA mismatch repair deficient endometrial cancer (0:00) Immunotherapy for mismatch repair-proficient endometrial cancer (9:18) Ongoing Phase III trials evaluating immuno...

Featuring an interview with Dr Asim Farooq, including the following topics: Educating patients about ocular toxicities associated with anticancer therapies (0:00) Differentiating therapy-related ocular toxicities from symptoms not associated with anticancer drugs (3:44) Optimal prevention of ocular toxicities from antibody-drug conjugates; symptoms and management of central serous retinopathy (9:3...

Featuring perspectives from Dr Stephen Liu, including the following topics: Introduction: Journal Club with Stephen V Liu, MD (0:00) Case: A woman in her mid 40s with metastatic lung adenocarcinoma with a ROS1 fusion — Minesh Dinubhai Patel, MD (10:54) Case: A woman in her late 70s with metastatic lung adenocarcinoma with a HER2 mutation — Adam R Miller, MD (17:40) Case: A woman in her early 60s w...

Featuring perspectives from Drs Ajai Chari, Ian Flinn, Nikhil Munshi and Laurie Sehn, including the following topics: Part 1: Case Presentations and Clinical Decision-Making (0:00) Case: A man in his early 70s with diffuse large B-cell lymphoma (DLBCL) arising from follicular lymphoma — Ian W Flinn, MD, PhD (3:46) Case: A man in his late 50s with nongerminal center B-cell-like subtype DLBCL — Laur...

Featuring perspectives from Prof Jonathan Ledermann, including the following topics: Introduction (0:00) Case: An Asian woman in her early 80s with ovarian cancer and a gBRCA mutation receiving maintenance olaparib after surgery and adjuvant chemotherapy — Rao Mushtaq, MD (2:05) Journal Club with Prof Ledermann (7:58) Case: A woman in her mid 80s with gBRCA wild-type high-grade serous ovarian canc...

Proceedings from a daylong multitumor educational symposium in partnership with the American Oncology Network, featuring perspectives from Drs Ibiayi Dagogo-Jack and Suresh Ramalingam on recent advances and real-world implications in lung cancer. CME information and select publications

Proceedings from a daylong multitumor educational symposium in partnership with the American Oncology Network, featuring perspectives from Drs Brad S Kahl and Craig Moskowitz on recent advances and real-world implications in chronic lymphocytic leukemia and lymphomas. CME information and select publications

Proceedings from a daylong multitumor educational symposium in partnership with the American Oncology Network, featuring perspectives from Drs Rafael Fonseca and Krina Patel on recent advances and real-world implications in multiple myeloma. CME information and select publications

Proceedings from a daylong multitumor educational symposium in partnership with the American Oncology Network, featuring perspectives from Drs Neeraj Agarwal and Sandy Srinivas on recent advances and real-world implications in genitourinary cancers. CME information and select publications

Proceedings from a daylong multitumor educational symposium in partnership with the American Oncology Network, featuring perspectives from Drs Harold Burstein and Joyce O'Shaughnessy on recent advances and real-world implications in breast cancer. CME information and select publications

Featuring a slide presentation and related discussion from Dr Joshua Sabari, including the following topics: Recent updates from ASCO 2022 in the use of EGFR- and MET-targeted therapies (0:00) Targeting HER3 in patients with advanced non-small cell lung cancer (NSCLC) with and without EGFR mutations (16:04) Recent updates in therapy for patients with EGFR exon 20 insertion mutations (21:47) DESTIN...

Featuring an interview with Dr Joshua Sabari, including the following topics: Updates in the use of adjuvant targeted therapy for localized and metastatic non-small cell lung cancer (NSCLC); impact of the ADAURA trial (0:00) Factors in the selection of second-line therapy for patients with and without driver mutations (10:30) Role of immunotherapy for patients with driver mutations (14:26) Recent...

Proceedings from a daylong multitumor educational symposium in partnership with the American Oncology Network, featuring perspectives from Drs Rutika Mehta and Philip Philip on recent advances and real-world implications in gastrointestinal cancers. CME information and select publications

Featuring a slide presentation and related discussion from Dr Alexander Spira, including the following topics: Incidence and spectrum of KRAS mutations in non-small cell lung cancer (NSCLC) (0:00) Sotorasib for the treatment of NSCLC with a KRAS G12C mutation (2:06) Clinical data evaluating adagrasib for the treatment of NSCLC with a KRAS G12C mutation (9:44) Future directions in the care of patie...

Featuring perspectives from Dr Alexander Spira, including the following topics: KRAS mutations in patients with non-small cell lung cancer (NSCLC) (0:00) KRAS small-molecule inhibitors combined with targeted therapy or immunotherapy for patients with NSCLC (3:49) KRAS small-molecule inhibitors in patients with NSCLC and brain metastases (10:52) Future role of KRAS small-molecule inhibitors as adju...

Featuring perspectives from Dr Robin "Katie" Kelley, including the following topics: Introduction (0:00) Case: A man in his mid 80s with newly diagnosed hepatocellular carcinoma (HCC) who has a partial response with atezolizumab/bevacizumab — Minesh Dinubhai Patel, MD (15:01) Case: A man in his mid 60s with HCC and lung metastases (AFP = 30,000) who receives front-line atezolizumab/bevacizumab — W...

Featuring a slide presentation and related discussion from Dr Brian Slomovitz, including the following topics: Recent data with PARP inhibitors alone and in combination with other agents as maintenance therapy for advanced ovarian cancer; recent data with novel agents (0:00) Efficacy data with pembrolizumab/chemotherapy from the KEYNOTE-826 trial; biologic rationale for targeting tissue factor and...

Featuring an interview with Dr Brian Slomovitz, including the following topics: Comparative efficacy and safety of commercially available PARP inhibitors for ovarian cancer (OC) (0:00) Patient- and disease-specific considerations in the selection and sequencing of treatment for OC with BRCA mutations (11:39) Mechanism of action of mirvetuximab soravtansine; recent efficacy and safety data with mir...

Featuring perspectives from Dr Samuel Klempner, including the following topics: Introduction (0:00) Case: A man in his mid 70s with gastric adenocarcinoma and oligometastatic disease to the liver (PD-L1 10%, HER2-positive) — Ranju Gupta, MD (2:47) Case: A man in his early 70s with locally advanced HER2-positive gastroesophageal junction (GEJ) adenocarcinoma who undergoes chemoradiation therapy and...

Featuring an interview with Dr Ezra Cohen, including the following topics: Spectrum of targetable mutations in thyroid cancer and impact on treatment selection (0:00) Comparative efficacy of TRK inhibitors in patients with thyroid cancer, including those with CNS disease (6:06) Current and emerging roles of immunotherapy alone and in combination with tyrosine kinase inhibitors for patients with he...