Paul Wicks

Prove It

Technology EN ↓ 6 episodes

The show where digital health leaders stop hand-waving, start evidence-building, and reveal how extraordinary claims become extraordinary results. Each episode I’ll be joined by someone who’s had their ideas tested in the fire of peer review, regulators, and the real world.

Author

Paul Wicks

Episodes

Regulation Is Not the Enemy of Speed Tauseef Mehrali on Building Safety Culture at 400 million Users 07.05.2026 51:49

Paul Wicks sits down with Dr. Tauseef Mehrali , GP, former VP of Medical Safety at Ada Health, and now VP of Regulatory Science at Flo Health, the world's largest femtech platform, for a deeply practical conversation about what it actually takes to build safety and regulatory rigour into digital health products at scale. Flo has over 400 million downloads and nearly 80 million monthly active users...

Hugh Harvey on Radiology AI Startups, Regulation, Evidence & the Only Way to Win in Health Tech 15.04.2026 49:43

In 2015 Geoffrey Hinton said radiologists would lose their jobs to AI within five years. It's 2026 and we're still short of radiologists. Dr. Hugh Harvey has a few thoughts on that. Paul Wicks sits down with Hugh, radiologist, ex-Babylon Health, Europe's first CE-marked deep learning mammography device, and now regulatory consultant to over 150 medical device companies, for a masterclass on why mo...

Can a Chatbot Really Care? Woebot's Founder on Therapeutic Bonds, CBT, and What LLMs Still Can't Do 31.03.2026 46:03

Before mental health chatbots were a trend, Dr. Ali Darcy was already running randomised controlled trials on one. In 2016, she and her collaborators at Stanford conducted what is widely regarded as the first ever formal RCT of a conversational AI for mental health. The paper has since been cited over 2,000 times. Her creation, Woebot, became one of the most studied and recognised digital mental h...

15 Years of Medical Rigour Over Hype: ADA Health's Daniel Nathrath, Building AI That Actually Works 19.03.2026 43:10

Digital health is littered with extraordinary claims that never collide with evidence. ADA Health is one of the rare exceptions. In this episode of Prove It, host Paul Wicks sits down with Daniel Nathrath, founder and CEO of ADA Health, to unpack what it actually takes to build medical-grade AI over 15 years without cutting corners on safety, rigour, or evidence. Daniel opens up about why he, a la...

The Secret Editor: The Brutal Truth About Peer Review, Profit, and “Bonkers” Publishing 26.02.2026 46:11

Medical publishing looks objective from the outside, but behind the curtain it’s a high-pressure, incentive-driven system where great science can get buried and mediocre work can slip through. In this special Prove It episode, Paul Wicks interviews a senior journal editor who remains anonymous (“The Secret Editor”) and explains how papers really move through the sausage factory: desk decisions, ed...

Placebo-Proof Digital Health: Why FDA-Grade Evidence (Still) Matters with Dr Acacia Parks 17.02.2026 53:26

Digital health is drowning in bold claims, so what actually counts as evidence? In this episode of Prove It! , Paul Wicks sits down with Dr. Acacia Parks (former Chief Science Officer at Happify, now VP of Regulatory Compliance & Engineering at Avania) to unpack the toughest questions in digital therapeutics: sham comparators, placebo effects, missing data, and what the FDA really expects. The...