Andy Wood, Matt Kirshen, Jesse Case
Probably Science
Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.
Author
Andy Wood, Matt Kirshen, Jesse Case
Category
Podcast website
Latest episode
Jul 6, 2026
Where to listen?
Podcasts in the app Replaio Radio Coming soonPodcasts are coming to the app soon. Install now and be the first to see a whole new take on podcasts
Episodes
Episode 412 - Marcus Brigstocke 23.01.2021 1:09:44
Comedian and actor Marcus Brigstocke ( @marcusbrig ) joins Andy and Matt to discuss blowing things up in school, puckle guns, coordinated electric eel attacks , solving the mystery of butterfly flight , separating dire wolf fact from fiction and giving shrooms to pigs .
Episode 411 - Frank Wilczek 15.01.2021 1:17:37
Nobel laureate Frank Wilczek ( @FrankWilczek ), author of the new book Fundamentals: Ten Keys to Reality , joins Matt and Andy to talk about the work that earned him a Nobel Prize, as well as his book, which delves into the essential concepts that form our understanding of how the universe works, digging into fundamental ideas like time, space, matter, energy, complexity and complementarity. This...
Episode 410 - Ed Byrne 07.01.2021 1:26:17
Comedian Ed Byrne ( @MrEdByrne ) joins Matt and Andy to discuss spiteful octopuses punching fish , using AI to solve protein structures , why recycling doesn't happen as much anymore (and Taiwan's amazing waste turnaround ), and Europe's plan for a space claw to capture orbiting junk . This episode is brought to you by The Great Courses Plus , offering Probably Science listeners a free 14-day tri...
Episode 409 - Dr. Peter McGraw 18.12.2020 1:27:20
Author, podcaster and behavioral economist Dr. Peter McGraw ( @PeterMcGraw ) returns to the show to talk with Matt and Andy about behavioral economics, cognitive biases, hellish comedy gigs, the science of humor, The Philadelphia Incident , Peter's new book Schtick to Business , stigmas surrounding unmarried life, flaws in happiness studies, how to support an aging populace that isn't being replac...
Episode 408 - Alex Schmidt 10.12.2020 1:12:43
Returning guest Alex Schmidt ( @AlexSchmidty ) of the podcast Secretly Incredibly Fascinating joins Andy and Matt to swap Jeopardy stories and discuss Doug the cat ruining equipment, grapefruit facts, The Ray Cat Solution to use glowing cats to warn future humans about radioactive waste , the monolith in Utah , Europa's mysterious glow and a beetle you can run over with a car . This episode is br...
Episode 407 - Megan Gailey 05.12.2020 1:10:28
Comedian Megan Gailey ( @megangailey ) joins Matt and Andy to talk about honeybees flying sideways , acoustic camouflage on earless moths , new moon rocks , meatless diets and brittle bones , the coolest dinosaur skeletons ever , fossil-hunting laws and Megan's podcast The Greatest .
Episode 406 - Charlie Fonville 21.11.2020 1:15:28
Producer and current Jeopardy champion Charlie Fonville ( @charliefonville ) joins Matt and Andy , whose four-day Jeopardy streak Charlie put an end to just yesterday, to talk about sharing the stage with the legendary Alex Trebek, the game theory of Jeopardy, including Daily Double and Final Jeopardy betting strategies , the Two-Thirds Rule , and Andy's odd-seeming bet when facing Stratton's Dile...
Episode 405 - Alex Falcone 11.11.2020 1:18:57
Comedian Alex Falcone ( @alex_falcone ) of the podcast Read It and Weep ( and a great NASA rejection letter ) joins Andy and Matt to talk about why Benford's Law doesn't apply to election data , Hamburglar voting irregularities , Andy's upcoming Jeopardy appearance (this Monday, November 16th), whether or not Alex Falcone was named after Alex Trebek, some good news on using psilocybin to treat dep...
Episode 404 - James Austin Johnson 29.10.2020 1:03:15
Comedian James Austin Johnson ( @shrimpJAJ ) returns to the podcast after a seven-year hiatus to talk about dinosaur butts , water on the moon , cell phone networks on the moon , shocking your tongue to cure tinnitus ... and for some reason President Donald J. Trump happens to call in to give his take on Sega Genesis reboots and lame duck hunts.
Episode 403 - Michael Marshall 24.10.2020 1:14:42
Author Michael Marshall ( @m_c_marshall ) joins Matt and Andy to talk about his new book The Genesis Quest , which explores the century-long effort to understand how life began on Earth and the many interesting characters who dedicated themselves to solving this massive scientific puzzle. This episode is brought to you by The Great Courses Plus , offering Probably Science listeners a free trial w...
Episode 402 - John Hastings 17.10.2020 1:25:49
Comedian John Hastings ( @thejohnhastings ) joins Andy and Matt to talk about the questionable comedy of Roy Chubby Brown , neanderthal genes and covid-19 , water bodies under the surface of Mars , and using balanced rocks to increase nuclear safety . This episode is brought to you by The Great Courses Plus , offering Probably Science listeners a free trial with unlimited access by visiting TheG...
Episode 401 - Gene Pompa 10.10.2020 1:12:10
Comedian Gene Pompa ( @genepompa ) joins Matt and Andy to discuss methanol-fueled robot beetles , super long words , methylated alcohol , why the moon is rusting , smartphones knowing when you're drunk-walking and corn that makes its own mucus .
Episode 400 - Brooks Wheelan and Jesse Case 26.09.2020 1:09:41
The gang's back together to celebrate 400 episodes of Probably Science! Erstwhile hosts Jesse Case ( @jessecase ) and Brooks Wheelan ( @brookswheelan ) join Matt and Andy to discuss counting magicians, Jesse's proximity to train tracks, Ig Nobel prizes for alligators on helium and narcissist eyebrows , detecting phosphine in the clouds of Venus , finding super old sperm in amber , an earthquake ha...
Episode 399 - Kat Arney 17.09.2020 1:07:10
Jesse Case rejoins the show for a cancer special with science writer Dr. Kat Arney ( @Kat_Arney ), author of Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal . This episode is brought to you by The Great Courses Plus , offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably
Episode 398 - Jen Burton 01.09.2020 1:03:53
Comedian Jen Burton ( @jensburpin ) joins Matt and Andy to discuss Africa getting rid of wild polio , painting turbine blades to save birds , a Jeopardy furry champ, an uncuttable material and Idyllwild's very good boy Mayor Max .
Episode 397 - Mia Jackson 29.08.2020 1:00:06
Mia Jackson ( @miacomedy ) join Matt and Andy to talk about old-time casino heists, asteroids that are the greatest basketball player of all time , ancient Americans , songbirds warming up and 100-million-year-old microbes that are still alive . Check out Mia's performances on Unprotected Sets on Epix, and her Comedy Central half hour . This episode is brought to you by The Great Courses Plus ,...
Episode 396 - Adam Cayton-Holland 22.08.2020 1:01:06
Despite a technical glitch, the excellent Adam Cayton-Holland ( @CaytonHolland ), star of Those Who Can't, the new podcast The Grawlix Saves The World , and his new album Semblance of Normalcy , talks with Andy and Matt about the word stentorian , Earth's magnetic anomaly , scientific collaborations and X shapes in the galaxy , finding out there's more than one foot , the threat of swooping magpie...
Episode 395 - Lynn Ferguson 15.08.2020 1:16:34
Writer, actress and story coach Lynn Ferguson ( @lynnfergy ) joins Matt and Andy to talk about house snooping and fountain misuse, chickens, wasps in figs , coyote melons, spying on penguin poop , Andy's hiking discovery , painting eyes on cow butts and whether hot water freezes faster than cold . Check out Michelle Biloon's album Permanent Hat and Sara Schaefer's book Grand !
Episode 394 - Jon Reep 06.08.2020 58:07
Matt's Last Comic Standing buddy (and Season 5 winner) Jon Reep @jonreep joins Matt and Andy to talk about getting COVID, meteors and moons , Shazam for spiders , anus-escaping water beetles , unusual places to grow a penis , medieval antibiotics , Jon's new podcast Country-ish and this totally independent, unbiased ranking of podcasts that we hope to break. This episode is brought to you by The...
Episode 393 - Mike McShane 26.07.2020 59:38
Improv and comedy acting legend Mike McShane ( @thismikemcshane ) joins Matt and Andy to talk about the funniest kind of nudity, cognitive impairment tests, the limits of human eating , the star that's hurtling across the universe , a sperm robot story we've done before , and mathematicians boycotting the police . This episode is brought to you by The Great Courses Plus , offering Probably Scienc...
Episode 392 - Jonah Ray 16.07.2020 1:15:32
Comedian Jonah Ray ( @jonahray ), host of Jonah Raydio and co-guest with Matt on TONIGHT'S episode of The Great Debate on Syfy, talks about his great Seeso show Hidden America , taking over MST3K (and his favorite episode ), how flying snakes fly , hungry hungry black holes , Twitter hacks and Bitcoin scams , talking to prairie dogs and the coming population crash . This episode is brought to you...
Episode 391 - Steph Tolev 10.07.2020 1:11:33
Comedian Steph Tolev ( @StephTolev ) joins Andy and Matt from Toronto to discuss quarantining and TikTok-ing with her family , the history of sled dogs , a black neutron star discovery , putting sheep in K-holes and a $23 million space toilet .
Episode 390 - Chris Garcia 04.07.2020 55:47
Comedian and host of the outstanding podcast Scattered Chris Garcia ( @_chrisgarcia ) joins Matt and Andy to discuss getting a little too much parental help with science fair projects, dolphins using tools , 3D printing inside the body and how burning coal 250 million years ago led to climate change . This episode is brought to you by The Great Courses Plus , offering Probably Science listeners...
Episode 389 - Matthew Broussard 26.06.2020 1:16:14
Comedian, swimmer and math major Matthew Broussard ( @mondaypunday ) joins Andy and Matt to talk about linear algebra, swimming , neanderthal DNA , DNA degradation , Alex Falcone's NASA career , ancient Irish one-percenters , twins marrying twins and twin paternity tests . This episode is brought to you by The Great Courses Plus , offering Probably Science listeners a free trial with unlimited acc...
Episode 388 - Jake Johannsen 16.06.2020 1:09:26
Comedian Jake Johannsen ( @Jakethis ) of the podcast Jake This joins Andy and Matt to discuss an herbal would-be COVID-19 remedy out of Madagascar , why men and women experience alcohol differently , alcohol's lack of protection against COVID-19 and appearing on Dr. Katz .
Similar podcasts
Replaio is not a podcast publisher; show names, artwork and audio belong to their authors and are distributed through public RSS feeds.