Andy Wood, Matt Kirshen, Jesse Case
Probably Science
Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.
Author
Andy Wood, Matt Kirshen, Jesse Case
Category
Podcast website
Latest episode
Jul 6, 2026
Where to listen?
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Episodes
Episode 262 - Casey Ley 15.09.2017 1:10:20
Comedian Casey Ley ( @caseywley ) joins Andy and Matt to talk about Andy's car, gay genes , gay face and AI , the first openly gay guy ever , snow leopards becoming less endangered , the end of Cassini , whether or not Saturn would float in water , the first live 4K video from space , the life of Sam Blackman , and Casey's podcast . This episode is brought to you by Hello Fresh. Visit hellofresh.c...
Episode 261 - Sara Benincasa 08.09.2017 54:25
Comedian and author of Real Artists Have Day Jobs (and three other books) Sara Benincasa ( @SaraJBenincasa ) invited Matt and Andy into her kitchen to talk about Burning Man, Woodstock '99, talking people down from drugs, creating cryptocurrencies , Space Camp vs. Space Academy, whiskey dilution , faces trained on Skype , Zika for brain tumors , and the secret messages contained in dogs' sneezes...
Episode 260 - Dipak Srinivasan 21.08.2017 1:19:26
Applied Physics Laboratory engineer (and Andy's old college roommate) Dipak Srinivasan returns to the podcast to talk about his work on the Mercury MESSENGER mission , the Pluto New Horizons flyby (that'll also soon be visiting Kuiper belt object 2014 MU69 ), and most importantly, the upcoming Parker Solar Probe and a mission to Jupiter's moon Europa , the most likely place in our solar system to...
Episode 259 - Kara Klenk 12.08.2017 1:06:09
Comedy's Kara Klenk ( @karaklenk ) joins Matt and Andy to talk about why Trump isn't good for comedy , bad forensics , hungry thinky worms , penis biting, bleach enemas to cure autism , slugs , Canaanites who just won't die and The Goldwater Rule .
Episode 258 - Heather Thomson 02.08.2017 1:14:23
Comedian Heather Thomson ( @CasualVelvet ) joins Andy and Matt to discuss early email addresses, Woodboys, laws of mathematics that don't apply in Australia , why chimps are pussies , how humans can out-jog horses , antibiotic lies , reversing brain damage with oxygen , Moon water , and the avocado hand epidemic .
Episode 257 - Jim Hegarty 20.07.2017 50:39
Comedian Jim Hegarty ( @jimhegarty ) joins Matt and Andy to talk about good and bad TV, the Up Series , fireworks contamination , dog domestication , junk DNA , the crazy fly book price , Brewster's Millions rules, egg shapes and egg refrigeration .
Episode 256 - Jason Reich 12.07.2017 1:14:04
Jason Reich ( @jasonmreich ), the head writer of The Jim Jefferies Show , joins Matt and Andy to discuss eating street apples and syringes, Vegas strategy, an HIV cure , why job interviews are bullshit , old dads with geeky sons follow-up, gonorrhea vaccines , vaquitas , fireworks technology , Alex Jones before and (redder) after and what Goop has in common with Infowars .
Episode 255 - Dr. Jane Gregory 04.07.2017 1:18:52
Cognitive behavior therapist Dr. Jane Gregory joins Matt and Andy to talk about her work and how she helps people suffering from anxiety, post-traumatic stress disorder, obsessive-compulsive disorder and more, along with her fantastic blog Cognitive Behave Yourself in which she puts her money where her mouth is and subjects herself to some of the techniques that she asks her patients to use.
Episode 254 - Maggie Maye 26.06.2017 1:08:24
Comedy's Maggie Maye ( @Maggiemayehaha ) joins Matt and Andy to discuss first TV bed-sharers , rival Amarillo songs, coconut oil , why it's too hot to fly , heat-based reptile sex swapping , older dads and geeky sons , neutron decay , lying chatbots and wobbling suitcases .
Episode 253 - Lucas Kavner 16.06.2017 1:21:45
Writer and comedic actor Lucas Kavner ( @lucaskavner ) joins Andy and Matt to talk about rebooted shows, reporting on robots, dog and wolf sharing , how breakfast affects benevolence , Einstein's impossible experiment finally performed , gut bacteria and dinosaur sex .
Episode 252 - Curtis Cook 08.06.2017 1:08:27
Comedian Curtis Cook ( @Curtis_Cook ) writes with Matt on The Jim Jefferies Show , and he sits down to discuss fancy premiere parties and imposter syndrome, catapult-making, how depressing the first Peanuts comic strip is , how AI will beat humans at everything by 2060 , Moravec's paradox , dino feathers and scales , getting re-upped on your vaccines , rust getting unfairly blamed for tetanus an...
Episode 251 - Renee Colvert 02.06.2017 1:15:53
Renee Colvert ( @ReneeColvert ) of the hit podcast Can I Pet Your Dog? joins Matt and Andy to discuss Paris disagreements, dog podcasting, universal healthcare , Savage/Soundgarden, Australian healthcare, another LIGO victory , Janna Levin's book , the Parker Solar Probe , the monkey mafia who steal your stuff and sell it back to you for a cracker , measuring sheep pain , and hand-washing rules .
Episode 250 - Subhah Agarwal 25.05.2017 1:01:10
Comedian and Jim Jefferies Show writer Subhah Agarwal ( @Subhah ) joins co-writer Matt and Andy to talk about actuarial tables and suicide, copying comics, asteroid timing , river meandering , a perfect dino , stable flamingos , Italian vaccines , mussel gloop for scarring , pretty pics of Saturn's rings and a puffy styrofoam planet .
Episode 249 - Neil deGrasse Tyson 17.05.2017 1:06:08
Neil deGrasse Tyson ( @neiltyson ), astrophysicist, science communicator and author of the fantastic new book Astrophysics for People in a Hurry , joins Matt and Andy for a Definitely Science episode, discussing, well, the entire universe: Its origins, the forces that govern it, general relativity, the multiverse, dark matter, dark energy, the fact that the universe is under no obligation to make...
Episode 248 - Live from Bridgetown Comedy Festival with Dr. Betsey Brada, Dr. Bryan Horne and Hampton Yount 12.05.2017 1:22:37
Live from the 10th annual Bridgetown Comedy Festival in Portland, Oregon, Matt and Andy welcome Reed College professor and cultural anthropologist specializing in health and medicine in southern Africa Dr. Betsey Brada , anthropologist specializing in bardic song in contemporary Russia Dr. Brian Horne , and the voice of Crow on Mystery Science Theater 3000: The Return Hampton Yount ( @hamptonyount...
Episode 247 - Russell Howard 05.05.2017 1:01:37
Comedy powerhouse Russell Howard ( @russellhoward ) joins Matt and Andy to chat about unintentional rudeness, new spider species , birds of paradise dances, Catalina and gerbil smuggling, more spiders, scaring off mice, artificial wombs and throwing things .
Bonus Episode from the March for Science 28.04.2017 41:54
Matt and Andy traveled to downtown LA's Pershing Square and City Hall to take part in the March for Science , along the way speaking with various groups who had set up booths for the event, and even a neuroscientist listener who took the time to chat about her work giving cocaine to mice. Don't forget that Probably Science (and Andy and Matt individually) will be performing live at Portland's Brid...
Episode 246 - Mary Mack and Tim Harmston 19.04.2017 1:07:52
Married comedians Mary Mack ( @marymackcomedy ) and Tim Harmston ( @timharmston ) sit down with Andy and Matt to talk about Frog rockets, orchestral doubling, Army band status, Guy Fawkes, accidentally melting science , dinobirds , kids with beaks, triple yolks, yogurt toppings economics, the book-stacking problem and why shoelaces come untied .
Episode 245 - Bryan Vokey, Carmen Morales and TJ Chambers 14.04.2017 1:09:17
Comedians Bryan Vokey ( @BryanVokey ), Carmen Morales ( @thefunnycarmen ) and TJ Chambers ( @tjchambersLA ) join Andy and Matt to discuss Georgia creationism, sperm-delivered drugs , erogenous T-Rex noses , geological Brexit , Segways on boats, Andy's mathematics puzzle, hamsters on Viagra and how memories are made .
Episode 244 - Henry Phillips 05.04.2017 1:19:05
Returning guest Henry Phillips ( @henlips ) of Punching Henry fame sits down with Matt and Andy to discuss graphene water filtration , a real-life (sort-of) Iron Man , funny foreign names, CT scan risks , CTs vs. MRIs, biologics, dumb/smart interview questions and the probability of rude names happening randomly.
Episode 243 - MK Paulsen 28.03.2017 1:26:01
Comedian MK Paulsen ( @mkpaulsen ) joins Matt and Andy to talk about Crazy Frog , public policy, October Sky, RIP radioactive boy scout , a heart of spinach , German fake suns , beating cancer and stopping aging , corrections corner, Andy's new swim teammate, strep, the Ten Commandments, tits on Nazis and chimp death rituals .
Episode 242 - Phoebe Bottoms and TJ Chambers 18.03.2017 1:10:13
Comedian Phoebe Bottoms ( @phoebebottoms ) and returning guest TJ Chambers ( @tjchambersLA ) join Andy and Matt to discuss the Boaty McBoatface submarine , sirens and pigs , breaking up with your physics teacher, naughty snooping dildos , microphones in your pocket, why avoiding gluten might hurt you , unvaccinated Australians , OCD , which animals you can't keep as pets , why plastic is still ba...
Episode 241 - Candice Thompson 10.03.2017 58:31
Hot on the heels of her recent Tonight Show appearance , comedian Candice Thompson ( @jokesbyCandice ) joins Matt and Andy to talk about Punching Henry, the movie Matt is in with Henry Phillips , ASMR, Richard Simmons , anti-Brit racism, what zoo animals taste like , Neanderthals' medication , mini-pigs and films about them, iCondoms , 3D printing medical supplies and pizzas , swimming pool pee ...
Episode 240 - Johnny Pemberton 03.03.2017 1:04:54
Comedian and actor Johnny Pemberton ( @johnnypemberton ) of Son of Zorn joins Matt and Andy to discuss water shortage solutions and Indiegogo lies , pipe bombs, ulcerative colitis, money you can piss on, a better way to crowdsource , training bees to play with balls , chiropractic, more opinions on cats and toxo, saving polar ice and eating da poo-poo .
Episode 239 - Kate Willett 22.02.2017 50:13
Comedian Kate Willett ( @katewillett ) joins Andy and Matt to talk about NASA's big exoplanet announcement and Episode 70 of our show discussing exoplanet research , the twin paradox , twin astronauts , fake Twitter accounts, a study showing that cats may not make you crazy , and a chiropractor's creative menstrual invention .
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