Andy Wood, Matt Kirshen, Jesse Case

Probably Science

Comedy EN ↓ 623 episodes

Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.

Author

Andy Wood, Matt Kirshen, Jesse Case

Category

Comedy

Podcast website

probablyscience.com

Latest episode

Jul 6, 2026

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Episodes

Episode 362 - Chris Mancini 21.11.2019

Comedian/writer/podcaster Chris Mancini ( @chrisjmancini ) of Comedy Film Nerds joins Andy and Matt to talk about the good Kickstarter for his graphic novel Rise of the Kung Fu Dragon Master (and a less-good one for this dumb wine thing ), what the deal with Pez is , toilet stickiness , Ohio religion laws , L'Hopital's rule , supernova blobs , pigeon bones , antibiotics resistance and why you may...

Episode 361 - Noah Gardenswartz 17.11.2019

Comedian Noah Gardenswartz ( @noahgcomedy ) of The Marvelous Mrs. Maisel joins Andy and Matt to discuss left-handed women's smell , cannibal ants , cg mustaches , an ebola vaccine , anti-vax Facebook ads , mouse deer and Mars air . This episode is brought to you by  The Great Courses Plus , offering Probably Science listeners a free trial with unlimited access to thousands of lectures by visiting...

Episode 360 - Chris Duffy 04.11.2019

Comedian and host of the radio show/podcast You're the Expert Chris Duffy ( @youretheexpert ) joins Matt and Andy to talk about rats driving cars , why measles is bad , the book Antisocial , fake news in Argentina, beavers on the moon , eagles racking up roaming charges , a thermal camera that spotted cancer , Google's quantum supremacy and the guy who coined the term , brewing beer in your stomac...

Episode 359 - Dr. Stuart Russell 31.10.2019

Artificial intelligence researcher and UC Berkeley Professor of Computer Science Dr. Stuart Russell joins Andy to talk about his new book Human Compatible: Artificial Intelligence and the Problem of Control , which explores the concept of intelligence in humans and machines, what the benefits and drawbacks of creating superhuman intelligence are, and what AI researchers can do now to help usher in...

Episode 358 - Daniel Dominguez 23.10.2019

Comedian-turned-writer Daniel Dominguez joins Matt and Andy to talk about his new animated Netflix series Seis Manos , Nobel Prize announcements in physics , medicine and chemistry , Ursula K. Le Guin , people with Goodenough names  and implanting false memories in birds . This episode is brought to you by  The Great Courses Plus , offering Probably Science listeners a free month of unlimited acce...

Episode 357 - Troy Walker 16.10.2019

Comedian Troy Walker ( @troywalkeresq ) joins Matt and Andy to discuss erector sets , owl pellets, scientists growing tooth enamel , aspen sunscreen , a Milky Way explosion , Dr. Magma , too many wallabies , university ripoffs and antibiotic resistance . This episode is brought to you by  The Great Courses Plus , offering Probably Science listeners a free month of unlimited access to thousands of...

Episode 356 - Matt Monroe 09.10.2019

Comedian Matt Monroe ( @heymonroe ) joins Andy and Matt to discuss retirement community shows, Sandler on Netflix, the Salton Sea , the toilet water scale , Terence Howard science , lizard womb babies , lady rabbit orgasms , Sarah Morgan's web series , a tooth bird fossil , Matt Monro and Born Free .

Episode 355 - Nick Turner 24.09.2019

Comedian Nick Turner ( @NicksTurners ) returns to the show seven years after his last appearance to talk about his podcasts  Get Rich Nick  and Recently Added , walking dogs, very slow zombies , a herpes vaccine , fun math with 3s , a new blackest black , Instant Hotel, cooking with ostrich eggs , Instant Hotel, Fastest Car and Hyperdrive, spiders flying with electricity and a play with a very con...

Episode 354 - Dr. Ria Lina 19.09.2019

PhD-having comedian Ria Lina  ( @rialina_ ) joins Matt and Andy to talk about bioinformatics, her research in viruses, specifically the herpes family of viruses, predicting this year's flu, the definition of life, the other kind of beach bodies, pathology, terrorism hypotheticals, herd immunity, viral ontology and Ria's ukulele song for Alabama . This episode is brought to you by  The Great Course...

Episode 353 - Nick Vatterott 13.09.2019

Comedian Nick Vatterott ( @vatterott ) of the new podcast Get Rich Nick joins Andy and Matt to discuss trivia, trypophobia , obscenity trials , mouthwash vs. exercise , vape deaths , Stackenblocken , a skull discovery , Lucy and whether there is a gay gene .

Episode 352 - "How To" author and xkcd creator Randall Munroe 05.09.2019

Cartoonist/author/engineer Randall Munroe of the Hugo Award-winning webcomic xkcd joins Matt and Andy to talk about his new book  How To: Absurd Scientific Advice for Common Real-World Problems , in which he gives novel, ridiculous and technically correct tips on doing everything from digging a hole to winning an election. You can catch Randall in person on his book tour running through September...

Episode 351 - Chris Martin and Hanna Stanbridge 29.08.2019

Comedians Chris Martin ( @ChrisMcomedy ) and Hanna Stanbridge ( @HannaStanbridge ) join Andy and Matt to talk about our Wired video , soap on a rope, some scientist listeners' corrections, burp-free cows and seaweed , July being the hottest month ever , how tongue rolling isn't fully genetic , vaccine-delivering Congo drones , asparagus pee, boney boners , Will Smith's penis, water-powered space c...

Episode 350 - Pollyanna McIntosh 22.08.2019

Actor/director Pollyanna McIntosh ( @PollyAMcIntosh ) of The Walking Dead, Lodge 49 and her directorial debut Darlin' joins Matt and Andy to discuss Dennis dentists, human-sized penguins , gay penguins with an egg , an ebola cure , good environmental news , bad environmental news  and  tails for old people . This episode is brought to you by  The Great Courses Plus , offering Probably Science list...

Episode 349 - Joyelle Johnson 19.08.2019

Comedian Joyelle Johnson ( @joyellenicole ) joins Andy and Matt to talk about doctor rules, chlamydia vaccines ,  AI that can spot bad food , our surprisingly old moon and an excellent Fidel Castro conspiracy theory .

Episode 348 - Jordan Doll 12.08.2019

Comedian Jordan Doll ( @razorlou ) joins Andy and Matt to discuss old UK comedy, field archaeology, being a shovel bum, King Arthur's various swords, massive parrots , the periodic table of Jeopardy! , tardigrades on the moon , disinfecting Mars, water-filtering wood , toxic Paris , Maya Angelou ads , problematic pics and The Mechanical Turk . This episode is brought to you by  The Great Courses P...

Episode 347 - KT Tatara 02.08.2019

Comedian KT Tatara ( @kttatara ) joins Matt and Andy to talk about a CRISPR sickle cell cure , a mysterious radiation leak linked to Russia , Mr. Wizard , Bob Lazar and UFOs and bees' sense of the electric fields of flowers . This episode is brought to you by The Great Courses Plus , offering Probably Science listeners a free month of unlimited access to thousands of lectures by visiting TheGreatC...

Episode 346 - Francisco Ramos 28.07.2019

Comedian Francisco Ramos  ( @FranciscoRamos ) joins Andy and Matt to discuss thermos technology, socialism, whether canned laughter works , an asteroid close call , quantum teleportation and an HIV cure for mice .

Episode 345 - Caitlin Weierhauser and TJ Chambers 17.07.2019

Comedian and recent Portland transplant Caitlin Weierhauser ( @UncleCait ) joins returning guest TJ Chambers ( @tjchambersLA ) to talk about the surprisingly extensive history of McDonaldland characters , how dogs' eyes evolved to appeal to humans , a notably droopy dog breed , a recently scrapped Indian space mission , female jockeys being underestimated by the betting public  , a recent study cr...

Episode 344 - Earthquake Talk with Jacob Margolis 11.07.2019

Jacob Margolis ( @JacobMargolis ), KPCC science reporter and host of the podcast The Big One , talks with Andy about the two recent major California earthquakes, what they mean for those living on nearby faultlines, what to do to prepare yourself for future quakes , FEMA's earthquake safety checklist , Jacob's supply shopping list and and his podcast detailing the repercussions of a hypothetical c...

Episode 343 - Dr. Alex Platt 04.07.2019

Population geneticist Dr. Alex Platt joins Matt and Andy to discuss the complex world of genetics and its role in shaping humans the world over, also dealing with the many misconceptions and blind spots people have about genetic diversity and the history of the human species.

Episode 342 - Susy Kane 24.06.2019

Actress/writer Susy Kane ( @kusysane ) joins Matt and Andy to talk about Stan & Ollie , eating a credit card's mass in plastic , a dubious claim about plastic straws , Canada's plastic ban , ISS tourism , InSight news , ladybug swarms and pterodactyls flying from birth .

Episode 341 - Bri Pruett 12.06.2019

Comedian Bri Pruett ( @bripruett ) joins Andy and Matt to discuss the invisible world, witchy things, a mosquito-killing GM fungus , saving the wasps , anxiety and gut bacteria , making kombucha, real plastic recycling and the resilience of tardigrades . See Matt in NYC next week . This episode is brought to you by Green Chef. For $75 off your first three orders, visit  greenchef.us/psp75 .   Come...

Episode 340 - Ismo Leikola 05.06.2019

Comedian Ismo Leikola ( @ISMOcomedy ) joins Matt and Andy to talk about Finland, language family trees, university physics, snails, LIGO news , a giant Australian meteor , chimps cracking open tortoises , generating power on ships and the fact that Ismo is the first thing that comes up when you do a video search for "ass."

Episode 339 - Michelle Biloon 16.05.2019

Comedian Michelle Biloon ( @biloon ) joins Andy and Matt to talk about RFK's assassination, credit card rules, Michelle's coding past, more cocaine in British sealife , living with MS, how kidney donor chains work and drones delivering organs .

Episode 338 - Tommy Johnagin 08.05.2019

Comedian Tommy Johnagin ( @tommyjohnagin ) joins Matt and Andy to discuss Last Comic Standing, finding your passion , why farts are funny, Marsquakes , crazy expensive houses, soil damage fueling climate change and a few ships polluting more than millions of cars.  

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