Chris Masterjohn, PhD
Mastering Nutrition
Welcome to the Mastering Nutrition podcast. Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks. He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University...
Author
Chris Masterjohn, PhD
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Podcast website
Latest episode
Dec 15, 2025
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Episodes
COVID-19: Blood Clots May Be the Cause of Low Oxygen Levels 24.04.2020 9:06
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: My Response to Dr. Rhonda Patrick on Vitamin D and ACE2 24.04.2020 9:59
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
What to do about premenstrual water retention? | Masterjohn Q&A Files #113 24.04.2020 4:49
Question: What to do about premenstrual water retention? Chris: I looked at a really good paper that showed that in women who had water retention symptoms with PMS, the main difference in their hormones was that they weren't clearing progesterone as fast from their ovulation-related peak. I was discussing this with a different friend who had found that she would consistently get water retention in...
COVID-19: Could Elderberry Cause a Cytokine Storm? Extremely Unlikely. 23.04.2020 10:01
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: Two Easily Available Lab Markers to Identify Patients at Risk of Severe Cases 23.04.2020 8:30
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
Dietary nutritional advice for breast cancer prevention and thoughts on HRT? | Masterjohn Q&A Files #112 23.04.2020 9:27
Question: Dietary nutritional advice for breast cancer prevention and thoughts on HRT? Carrie: Well, that's probably better for you when it comes to like nutrient ratios and stuff. But I will say working for an estrogen lab, we're looking at phase one and phase two detoxification and what we're trying to assess with estrogen. Men and women, we make estrogen, and then we detox our estrogen. We go t...
COVID-19: If You Lose Your Sense of Smell or Taste, What Are the Chances You Have It? 22.04.2020 5:13
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: The Nose Gets Infected, and the Nerves Get Damaged 22.04.2020 9:46
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
What are causes for night sweats in men?| Masterjohn Q&A Files #111 22.04.2020 4:22
Question: What are causes for night sweats in men? Carrie: Oh. Well, it can be hormonal just like it can be for women. I test all the same hormones in men. I check their thyroid with night sweats. I definitely even check the same thing. I check cortisol and I do norepinephrine markers with night sweats. This is also assuming that I don't suspect cancer because night sweats can be a key note, espec...
COVID-19: Getting Zinc and Copper Into the Nose, Mouth, and Throat 21.04.2020 8:27
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: It Infects the Throat, Not Just the Lungs 21.04.2020 7:40
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
With an ovary removed, when should I think about increasing progesterone or estrogen? | Masterjohn Q&A Files #110 21.04.2020 3:32
Question: With an ovary removed, when should I think about increasing progesterone or estrogen? Carrie: You may actually need more progesterone. Like I was saying in the very beginning of this, that progesterone actually turns into that neurosteroid allopregnanolone, which can cross the blood-brain barrier and bind itself to GABA and affect sleep. It's very calming, obviously relaxing. It's GABA....
COVID-19: What's the Best Dose of Zinc for Prevention? 20.04.2020 9:46
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: Are Quercetin and EGCG Beneficial? 20.04.2020 9:16
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
Why do I wake up early every morning when I'm depressed? | Masterjohn Q&A Files #109 20.04.2020 8:09
Question: Why do I wake up early every morning when I'm depressed? Carrie: Now, with depression, it's heavily studied if you have an elevated or excessive cortisol awakening response, meaning you go higher, your spike is higher and more dramatic than the average bear, then your risk for morning depression is much higher. The reason for that as we've already touched upon with estrogen and the serot...
COVID-19: Are Chloroquine and Hydroxychloroquine Zinc Ionophores? 19.04.2020 10:02
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: New Data Suggesting the Open Air Is Safe 19.04.2020 7:53
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: Why New York City Is a Leading Indicator, Not an Outlier 19.04.2020 7:33
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
COVID-19: How Much Worse Will This Get Before It Gets Better? 19.04.2020 5:39
Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have...
How does the body make hormones and what nutrients and foods do they need to do this? | Masterjohn Q&A Files #108 17.04.2020 12:48
Question: How does the body make hormones and what nutrients and foods do they need to do this? Carrie: Now, as far as nutrients go, like I said, cholesterol is the backbone to all of your hormones. Much like the gentleman who said earlier his cholesterol was quite low, it can impact the way and the amount of hormones that you make. The lower your cholesterol is, the tougher time you can have to m...
Should someone with low testosterone go back on testosterone replacement therapy or wait it out? | Masterjohn Q&A Files #107 16.04.2020 8:38
Question: Should someone with low testosterone go back on testosterone replacement therapy or wait it out? Carrie: Men have luteinizing hormone just like women do. It comes from the brain. It's what stimulates the testes to make testosterone. If you have low LH, then I know it's a brain problem, not necessarily a testicular problem. If your LH is normal, it's not in the brain. Chris: If the questi...
What to do about low libido after a LEEP procedure? | Masterjohn Q&A Files #106 15.04.2020 5:11
Question: What to do about low libido after a LEEP procedure? Carrie: With the LEEP procedure, so like I was saying, basically it's kind of like a hot knife through butter. They cut away a portion of the cervix. And it depends. Sometimes it's a little portion and sometimes they do what they call like a full big slider right across the face of the cervix. If you remember, for those of you who maybe...
Would a seasonally low vitamin D intake and high calcium intake cause soft tissue calcification? | Masterjohn Q&A Files #105 14.04.2020 5:09
Question: Would a seasonally low vitamin D intake and high calcium intake cause soft tissue calcification? Chris: Yeah, okay. The end of this question is would the calcium simply be excreted due to the low vitamin D levels. Your vitamin D level being low, the first thing that's going to do and the major thing that's going to do is it's going to lower your calcium absorption. You would have more ca...
Question on Iodine, Fatigue, and Detox Reaction. | Masterjohn Q&A Files #104 13.04.2020 6:23
Question: Question on Iodine, Fatigue, and Detox Reaction. Carrie: Remember, iodine belongs to the halogen family and other halogens can bind onto your PT or tyrosine. I have had this before where patients would take iodine and the iodine will push off the fluoride and the chloride and the bromide off of the tyrosine, and so it binds on and now you have essentially a detox reaction. People will sa...
How to lower Sex Hormone-Binding Globulin (SHBG)? | Masterjohn Q&A Files #103 10.04.2020 8:09
Question: How to lower Sex Hormone-Binding Globulin (SHBG)? Carrie: SHBG is like bane of my existence. I have no idea how to get SBHG down once it's up. Boy, I actually talk to practitioners about this all the time to figure that out. I would agree that supplements that for SHBG, it's very hit or miss, Tongkat being one of them, DHEA being the other. There are two other ones, stinging nettles and...
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