Chris Masterjohn, PhD
Mastering Nutrition
Welcome to the Mastering Nutrition podcast. Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks. He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University...
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Chris Masterjohn, PhD
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Latest episode
Dec 15, 2025
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Episodes
How Diabetes, Like Sugar, May Fuel Viral Growth 25.08.2020 21:28
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
Is hydrogen sulfide produced in the gut a bad thing, and what to do about it? | Masterjohn Q&A Files #129 25.08.2020 6:22
Question: Is hydrogen sulfide produced in the gut a bad thing, and what to do about it? I agree that most people that have this problem have some kind of deranged sulfur metabolism, but I don't see why that makes it a physiological adaptation rather than a pathological condition. The correlation is probably a direct result of the predominance of sulfur-metabolizing bacteria in the gut, which is a...
What if low-carb makes me wake up to pee? | Masterjohn Q&A Files #128 24.08.2020 4:42
Question: What if low-carb makes me wake up to pee? I would start by looking at your blood sugar. So I do think it's possible that if your blood sugar. Second of all, it's stimulated by salt. So salt at night might help. Third of all, in order to make it you need copper, vitamin C, and zinc. And then, fourth of all, you need, going past that, I also suggest trying to get deeper sleep. You might w...
Could Sugar Intake Play a Role in COVID-19? 24.08.2020 1:13:19
Watch the YouTube video to see the slides: https://youtu.be/Az0f6VPaEAA Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a cop...
How does someone get arachidonic acid and choline without eggs and liver? | Masterjohn Q&A Files #127 21.08.2020 3:04
Question: How does someone get arachidonic acid and choline without eggs and liver? So apart from liver and egg yolks, I think that it is very difficult to get enough arachidonic acid from food. Yes, GLA might help, but there's actually arachiodonic acid supplements. And for the vegans out there, I don't know if the production process is strictly vegan, but they are derived from a specific mushroo...
Whey Protein, Breast Milk, and COVID-19 21.08.2020 47:58
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
Nutritional suggestions for SI joint pain and sulfur sensitivity? | Masterjohn Q&A Files #126 20.08.2020 2:43
Question: Nutritional suggestions for SI joint pain and sulfur sensitivity? So certainly if it's autoimmunity, I'm thinking you might have problems with folate, where you might want to lower folate intake. You might benefit from having more A and D. You might benefit from removing hypothetically pro-inflammatory foods. Magnesium is important. Acid-base balance is important. Citrate is probably hel...
If it's easier to store fat than to convert carbs to fat, why is it easier to lose weight on low-carb? | Masterjohn Q&A Files #125 19.08.2020 5:55
Question: If it's easier to store fat than to convert carbs to fat, why is it easier to lose weight on low-carb? It's easier to store dietary fat as fat than it is to store dietary carbs. Why is it easier to lose weight on the keto diet than a higher carb diet assuming isocaloric? Well, I think there's an assumption that's not necessarily true there, but the ease with which you store something as...
Long-term shortness of breath after COVID-19: do I need iron? | Masterjohn Q&A Files #124 18.08.2020 9:30
Question: Long-term shortness of breath after COVID-19: do I need iron? I don't think there's any evidence that iron fuels COVID-19. And it's pretty clear that the systemic inflammation is driving dysregulation of iron in a way that hurts oxygen delivery. So it's very clear that low oxygen delivery is a major feature of COVID. And I think probably the bulk of that is due to clotting, but also infl...
Are liposomal supplements really superior? | Masterjohn Q&A Files #123 17.08.2020 1:57
Question: Are liposomal supplements really superior? I doubt it. So I think the evidence indicates that liposomes don't survive digestion unless they are pegylated, which means that they have polyethylene glycol that's attached to the liposome to protect them from digestion. There are a number of other such modifications that can be made, but I don't think that applies to most liposomal things on...
Vitamin K and COVID-19 17.08.2020 43:36
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
Treatment of COVID-19 With High-Dose Zinc: A Report of 4 Cases 16.08.2020 26:38
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
The Latest on Vitamin D and COVID-19 15.08.2020 33:43
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
Why would I develop shortness of breath on a carnivore diet? | Masterjohn Q&A Files #122 14.08.2020 1:22
Question: Why would I develop shortness of breath on a carnivore diet? That can happen in scurvy. So given that vitamin C is one of the higher-risk nutrients on a carnivore diet, that would be the first thing that I would look at. I'm glad it was short-lived. I think it's possible that there are vitamin C-sparing effects of a carnivore diet, but they take a little while to kick in. So as you trans...
Is it possible to meet all your nutritional needs on a carnivore diet? | Masterjohn Q&A Files #121 13.08.2020 11:00
Question: Is it possible to meet all your nutritional needs on a carnivore diet? So the short answer to this question is yes, but the longer answer to this question, as I just went through, is it's quite complicated. I've said it with respect to carnivore diets. I think it's good to look at nutrition, kind of like an economic portfolio. If you are very, very expert, you can know what you're doing...
Why are medium-chain fatty acids ketogenic even in the presence of carbs? | Masterjohn Q&A Files #120 12.08.2020 12:30
Question: Why are medium-chain fatty acids ketogenic even in the presence of carbs? It's all about the ratio. We know for a fact that MCT oil is ketogenic even in the presence of pasta, period, end of story. So, the question here is, biochemically, why is it happening? Well, they go into the mitochondria, even in the presence of insulin and a buildup of acetyl CoA over the incoming oxaloacetate. A...
What measurement of magnesium status is best to use for arrhythmias? | Masterjohn Q&A Files #119 11.08.2020 3:39
Question: What measurement of magnesium status is best to use for arrhythmias? I assume by "measure" you mean a measurement of nutritional status, in which case I think you want to look at the serum level. think that if you're trying to fix a problem with the serum level, you probably at some point want to look at the red blood cell level and the urine level. One of the ways that magnesium could i...
Is subclinical thiamine deficiency a contributor to many diseases? | Masterjohn Q&A Files #118 10.08.2020 7:25
Question: Is subclinical thiamine deficiency a contributor to many diseases? So in terms of like in terms of subclinical deficiency, is it common, does it exist? It is hard to answer because, as usual, most of the data that's clear is on severe deficiencies, but there are some studies. I wouldn't say that there's a huge body of literature. There are some studies suggesting that even if you take a...
COVID-19: How Safe Is the INDOOR Air? 02.08.2020 31:29
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
Can Aerosols Spread COVID-19? 01.08.2020 17:13
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass. Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismas...
How Dangerous Is the OUTDOOR Air for COVID-19? 31.07.2020 21:42
Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismas...
COVID-19 Antibodies Stay High But Lose Effectiveness Over Time 18.07.2020 18:10
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book Get the guide for free and get 30-50% off the pre-orders of my book wh...
COVID-19: The Three Immunotypes 17.07.2020 16:23
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book Get the guide for free and get 30-50% off the pre-orders of my book wh...
Does Exposure to Animals Provide Immunity to COVID-19? 15.07.2020 18:32
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book Get the guide for free and get 30-50% off the pre-orders of my book wh...
Low Potassium Levels in COVID-19 23.06.2020 17:36
Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book Get the guide for free and get 30-50% off the pre-orders of my book wh...
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