Longevity Optimization with Kayla Barnes-Lentz

Is your environment silently sabotaging your fertility? Dr. Ann Shippy joins the show to reveal how hidden toxins, mold, and overlooked cellular damage may be accelerating ovarian aging and how to reclaim your fertility before it’s too late. From infertility misdiagnoses to rising autism rates, we dive deep into the tests most doctors never run, and the real impact your body’s toxic load has on fu...

Ashley Koff is a registered dietitian and author who spent 20 years discovering that weight and health aren't separate issues, they're connected through "weight health hormones." After her own struggles with restrictive eating despite doing everything "right," a functional medicine doctor helped her understand what was actually broken, and that was, her body's natur...

In this video, Dr. Will Bulsiewicz shares his transformation from an overweight, depressed gastroenterologist to a gut health expert after meeting his now-wife changed his entire approach to food. He reveals why 95% of Americans are fiber deficient and how this single nutrient could be the key to longevity. Dr. B breaks down the science of the gut microbiome, explains why hyperpalatable foods forc...

Women don’t fail January — January fails women. Nearly 80% of New Year health goals are abandoned within weeks, not because of discipline, but because most plans ignore female biology. That’s why I created the 30-Day Female Longevity Challenge — a physiology-first way to prepare calmly and build health that actually lasts. Save $50 with code 2026. https://kayla-barnes-lentz.circle.so/checkout/fema...

In this conversation, Kayla sits down with Dr. Sarah E. Hill, PhD to talk about the science behind PMS, cycle syncing, and why most health advice completely fails women. Dr. Hill explains the three main causes of PMS symptoms, natural hormonal shifts, one-size-fits-all protocols designed for men, and lack of cellular resilience. Join the most comprehensive female-specific community for health and...

For years, functional medicine has focused on lab results and supplement protocols. Dr. Deanna Minich knows there's a deeper layer most practitioners miss. As a nutrition scientist who worked under Dr. Jeffrey Bland and educated for the Institute for Functional Medicine, she's witnessed how artificial light at night disrupts women's hormones more than almost any other factor, yet it's completely i...

Everyday “healthy” choices might be silently rewiring your immune system—from canned soup and tap water to perfume, makeup, and even your couch—while autoimmune diseases quietly explode, especially in women. In this gripping conversation, Dr. Aly Cohen reveals how under-regulated chemicals, hidden toxins, and epigenetic changes may be driving the autoimmune epidemic, but also how strategic swaps,...

In this episode, Kayla sits down with Dr. Karan Rajan, who is one of the most followed medical professionals on social media, and he breaks down the gut microbiome like you've never heard before. If you've ever felt bloated after eating fiber, tried keto and felt amazing temporarily, or wondered why your "clean" diet isn't delivering results, this episode is for you. They talk about why fiber is n...

Your home could be triggering your allergies and nobody's checking. Dr. Tania Elliott sees patients struggling with reactions that disappear before they can get to the doctor's office. That's why she started doing virtual home tours to find what's really causing the problem. In this episode, Dr. Elliott explains why that new couch smell is actually toxic, how synthetic candles mess with your hormo...

Are you planning to get pregnant, currently pregnant, or postpartum? This conversation with dietitian Lily Nichols will change how you think about nutrition during these critical life stages. Lily reveals that over 90% of women have nutrient deficiencies that directly impact fertility, pregnancy outcomes, and postpartum recovery. Most women have no idea they're lacking essential nutrients like...

Are you dealing with unexplained fatigue, hormonal imbalances, brain fog, or chronic inflammation that doctors can't figure out? In this episode, Dr. Jess Peatross explains why so many people are sick with "mystery symptoms" that doctors can't solve. She breaks down the toxins and infections making you sick, how to test for them properly, and her step-by-step "Kill Bind Sweat" detox method. So, if...

When a top surgeon faces his own health collapse, he’s forced to question everything he’s ever believed about medicine. In this gripping conversation, Dr. Darshan Shah reveals how hitting rock bottom led him to uncover the true keys to longevity — from biomarker mastery and advanced testing to the future of AI-driven health and gene therapy. This episode will make you rethink what it means to live...

Most people think heart disease is just about cholesterol. But what if the real issue is in your genes, your environment, and even your daily stress? In this episode, I’m joined by Dr. Christopher Davis, a triple board-certified interventional cardiologist who’s redefining what it means to take care of your heart. After years of performing stent procedures, he realized the conventional system was...

Brain coach Jim Kwik went from being called “the boy with the broken brain” to teaching millions how to unlock their limitless potential. In this episode, he reveals the simple shifts that supercharge focus, memory, and learning speed—helping you read faster, think clearer, and retain more. Discover why mindset, motivation, and method are the three keys to peak mental performance, and how to apply...

A lot of women are tired, busy, and trying to stay healthy. But what if you didn’t need to do everything perfectly to feel good? In this episode, we talk about the key parts of health that matter most. You’ll learn how much sleep your body actually needs, what kind of movement helps you stay strong, how to eat for steady energy, and why your relationships can change your health. We also talk about...

Dr. Brad Schoenfeld, PhD is one of the world’s leading researchers on muscle hypertrophy (muscle growth). He is a Professor of Exercise Science at Lehman College in New York, where he directs the Human Performance Laboratory. Over his career, he has published more than 300 peer-reviewed articles, book chapters, and textbooks on resistance training, body composition, and nutrition. He is the author...

For years, women have been told that birth control or IVF are the only solutions to reproductive issues. Dr. Naomi Whitaker knows that’s not the full story. Through Restorative Reproductive Medicine, she helps women identify the deeper health imbalances that fuel infertility, endometriosis, PCOS, and hormones, and shows how healing the body’s natural rhythms can change everything.  In this episode...

Today I’m joined by Dr. Lara Briden, a naturopathic doctor, best-selling author, and internationally recognized expert in women’s hormones for a wide-ranging conversation on cycle health and why ovulation is a vital sign of wellbeing. We talked about how monthly ovulation creates hormones that support bones, metabolism, and brain function, and what happens when that rhythm is disrupted by stress,...

Join us in this insightful episode as we sit down with Dr. Ja-Nae Duane, a behavioral scientist, futurist, and bestselling author. We delve into the intersection of exponential technology, human systems, and the future of health. Discover how Dr. Duane's journey from opera singer to futurist informs her mission to improve life for a billion people. Chapters: Introduction to Dr. Janaye Duane (0...

Brigid Titgemeier, a functional medicine dietitian and founder of Being Brigid Nutrition, has seen countless women walk into her clinic exhausted, bloated, and frustrated despite eating all the right foods. She knows that feeling firsthand, too. Instead of blaming willpower or cutting out everything you love, Brigid discovered how simple, personalized nutrition changes could completely shift energ...

What if aging wasn’t just something that happens to us, but something science could actually slow down? That’s the question at the heart of today’s conversation with Dr. Matt Kaeberlein, who’s a leading scientist and longevity researcher at the University of Washington. Dr. Kaeberlein has spent decades decoding the biology of aging, from cellular mechanisms to practical strategies that could exten...

Join us in this powerful episode as we sit down with Dr. Natalie Crawford, a double board-certified OB/GYN and reproductive endocrinologist. We explore her personal journey with recurrent pregnancy loss, the rising rates of infertility, and the impact of inflammation, toxins, and lifestyle on reproductive health. Discover how Dr. Crawford is reshaping fertility care and empowering women to underst...

Today I’m joined by Dr. Bill Rawls, a board-certified physician and bestselling author, for a wide-ranging conversation on chronic illness, healing, and what it really takes to protect long-term health. We dive into the challenges people face when conventional medicine falls short, the role of lifestyle and environment in recovery, and the surprising power of natural approaches to restore balance...

Today I’m joined by Dr. Brooke Stubbs, a double board-certified physician in internal and lifestyle medicine, for a deep dive into inflammation, what drives it, how it shows up in the body, and why so many women are silently affected by it. We explore how gut dysfunction, hormone imbalances, poor sleep, and emotional stress contribute to chronic symptoms like fatigue, bloating, brain fog, and burn...

In this conversation, I sit down with Nick to unpack the deeper science behind GLP-1s and metabolic health. We explore how compounds like Tirzepatide and GLP-1 agonists go beyond weight loss, influencing everything from cardiovascular elasticity and neuroinflammation to mood, cognition, and gut-brain signaling. We also discuss lesser-known drivers of real change, like adiponectin, MPO, and the sur...