LEVELS – A Whole New Level

From gallbladder issues to tinnitus to fatty liver disease and more, many chronic conditions have links to high blood sugar and insulin resistance. Dr. Ben Bikman and Dr. Casey Means discuss the connections between insulin resistance and ear-nose-and-throat conditions, how insulin resistance increases the risk for gallbladder stones, what non-alcoholic fatty liver disease does to the body, and how...

Medications, such as Ozempic, Wegovy, and more, have become increasingly popular for weight loss. These drugs are glucagon-like peptide 1 (GLP-1) receptor agonists, and they mimic a hormone that, among other things, tells the brain a person is full so they eat less. But are they safe, and do they help improve metabolic health? Dr. Rob Lustig and Dr. Casey Means discuss these weight-loss drugs and...

We know sugar is bad for kids, so why do parents continue giving it to them? Sugar damage kids’ health and drives behavioral issues. Infants get introduced to sugar early through commercial baby food, and the problem continues with school and birthday treats, soda, and the ultra-processed foods that have taken over the family pantry. Austin McGuffie & Dr. Robert Lustig discuss the rising rates...

The ketogenic diet may help reduce depression and other symptoms in bipolar disorder. The ketogenic diet also helps metabolic health and reduces the risk for cardiometabolic diseases. The risk for cardiometabolic diseases is elevated in people with bipolar disorder when compared to the general population. Dr. Iain Campbell, Dr. Bret Scher, and Dr. Dominic D’Agostino discuss how the state of ketosi...

The United States government subsidizes ultra-processed foods and sugar, and the healthcare system focuses on treating diseases rather than preventing them. These issues are harming kids’ health and leading to crisis-level rates of prediabetes and diabetes in both adults and children. Siblings Calley Means and Casey Means discuss problems with the food industry, government funding, and healthcare,...

How might a keto diet transform not only your metabolic health but may also manage symptoms of mental health disorders like depression, anxiety, PTSD, schizophrenia, and more? Dr. Chris Palmer outlines the principles from his book “Brain Energy” with Ben Grynol in this episode and discusses his journey toward the revolutionary idea that might change how we view mental health care moving forward. S...

Continuous glucose monitoring can be a powerful tool for gaining real-time insights into how diet, lifestyle habits, and the many decisions we make daily affect our health. Retired astronaut Scott Kelly tried a CGM for a month and shares his personal insights. Scott Kelly and Josh Clemente discuss how CGM can be used to effect habit change, what Kelly’s participation in the unique NASA Twins study...

Why do women have a higher risk of metabolic dysfunction and cardiovascular disease than men, and how do women move forward as empowered patients with their clinicians? Listen to this episode between Levels Advisor, physician, and author 4 New York Times bestsellers Dr. Sara Gottfried and Levels Co-Founder and Chief Medical Officer Dr. Casey Means. Sign Up to Get Your Free Ultimate Guide to Glucos...

Ultra-processed foods harm people’s health and have ramifications for the overall health of the planet. While some food processing is necessary for recipes and feeding the globe, the food industry needs to make changes to ensure that processing doesn’t turn foods into harmful substances. Dr. Tim Harlan and Dr. Rob Lustig discuss the harmful ingredients in ultra-processed foods and how they impact...

Why are we craving food more than ever, and how do we overcome it? Mark Schatzker, journalist and author of The End of Craving: Recovering the Lost Wisdom of Eating Well, chats with Dr. Casey Means about the dangers of food cravings. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellne...

Biosensing offers people real-time insight into their health status. Regular insight, rather than one-time results at an annual checkup, helps people assess how lifestyle factors are impacting their health, whether they need to make adjustments, and which adjustments might have the most impact. Michael Dubrovsky and Josh Clemente discuss the value of biosensing and how it has the potential to disr...

We often think that arthritis, musculoskeletal pain, and degenerative joint issues are an inevitable result of aging—but this is far from the truth. Good metabolic health can have significant positive effects on bones, muscles, and joints, and can improve longevity. Conversely, poor metabolic health accelerates the degeneration of joints and tissues for many reasons, like the impact of high uric a...

Fructose and its byproduct uric acid may play a role in the development of Alzheimer’s, thanks to an evolutionary adaptation hijacked by the modern diet. Fructose can be directly consumed, or the body can convert high-glycemic carbohydrates and other foods to fructose. Fructose suppresses some cognitive functions. Dr. Richard Johnson and Dr. Rob Lustig discuss a new study, of which Johnson was an...

The elevation of uric acid in the body is a causative mechanism in the development of metabolic diseases and contributes to weight gain and fat production. Uric acid is one of the key links between obesity, diabetes, heart disease, neurologic diseases like dementia, ADHD, non-alcoholic fatty liver disease, and more. Dr. David Perlmutter talks with Dr. Casey Means about why we have excess uric acid...

Receiving a diagnosis of a chronic condition, such as Type 1 diabetes, can be life-changing. A diagnosis is helpful for understanding the cause of symptoms and how to treat, but managing a chronic condition can take a toll on mental health. Tools like a continuous glucose monitor can help empower people and ease the burden of constant care. Jesse Lavine and Ben Grynol discuss the challenges of man...

A metabolic blood test and cholesterol panel can be confusing, so in this ultimate guide, our Chief Medical Officer and Co-Founder Dr. Casey Means talks with Levels advisor and author of Metabolical to give you advice on how to interpret your panels to better understand the status of your metabolic health. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversati...

How does pregnancy affect your metabolic health at each trimester, from conception to postpartum lactation? Levels Research Design Lead Dr. Azure Grant talks with Ben Grynol about the different phases of pregnancy and how it affects hormones and things you can do to reduce the risk of gestational diabetes. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversati...

Insulin resistance is when cells stop responding to insulin’s signal to uptake glucose. It’s a hallmark of prediabetes, Type 2 diabetes, and other forms of metabolic dysfunction, and it manifests as several chronic disease, ranging from Alzheimer’s to polycystic ovarian syndrome. Dr. Rob Lustig and Dr. Dominic D’Agostino discuss the importance of monitoring insulin levels, why a high or increasing...

High-carbohydrate diets and carbohydrate loading have been long-standing tenets of athletic training and competition, but newer research indicates a low-carbohydrate diet may be more beneficial for performance and overall health. Professor Tim Noakes and Josh Clemente discuss how a fat-adapted body can rely on fat as a fuel source at all exercise intensity levels, rather than burning mostly carboh...

Society champions multitasking, but we can’t truly multitask. Multitasking in fact impedes our focus and productivity. And 12 main factors tend to steal our attention. Johann Hari and Ben Grynol discuss why flow states are important for goal achievement, the things that distract us, and how we can reclaim our focus. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels...

Regenerative farming harnesses a farm’s entire ecosystem to grow and raise food via natural processes. In turn, foods raised on regenerative farms benefit our bodies more so than those raised conventionally. Molly Chester of Apricot Lane Farms and Dr. Casey Means discuss the philosophies of regenerative farming, how the practice has parallels with functional medicine, and how regenerative farming...

Gastrointestinal health, metabolic health, and fertility are all linked. The gut microbiome impacts other microbiomes in the body, which can then impact the ability to conceive. Our gut microbiomes are becoming less diverse through modern farming practices and the consumption of processed foods. Dr. Robin Rose and Ben Grynol discuss how gut microbiome testing can determine underlying factors of ga...

Concierge medicine can help personalize healthcare and disrupt the traditional primary care model. Traditional primary care isn’t positioned to handle the frequent check ins and actionable steps that empower patients to optimize their health and wellness. Chloe Harrouche and Mike Haney discuss The Lanby, which Harrouche co-founded. The Lanby’s primary care membership provides patients with a three...

The ketogenic diet, intermittent fasting, and other nutritional strategies for metabolic health are unique when it comes to the female body. Hormonal changes over the menstrual cycle trajectory matter. Dr. Stephanie Estima and Dr. Lauren Kelley-Chew discuss women’s metabolic health, how to time nutritional strategies with the menstrual cycle, and why strength training is key. Sign Up to Get Your F...

The hallmarks of aging are various biomarkers that indicate advancing biological age, which leads to a decline in health and eventually to death. But we can boost longevity by understanding aging biomarkers and then taking actionable steps with nutrition, physical activity, and environment. Dr. Mark Hyman and Dr. Casey Means discuss the hallmarks of aging and the factors that are within our contro...