John Holcombe
JH Leadership & Strategy: Monetizing Innovation
Where big ideas become real results. This podcast explores how forward-thinking leaders turn innovation into impact, strengthen teams, and move strategy into action. Each episode features energizing conversations with top innovators across life sciences, healthcare, and tech, along with John’s practical insights from decades of helping leaders gain clarity, execute with confidence, and drive meaningful change. Tune in, level up, and make innovation count.
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Episodes
Driving Innovation in Pharma: Insights from Hardeep Kaur 07.07.2026 35:26
The conversation delves into the intersection of people, technology, and processes in driving transformation within large pharmaceutical companies. It emphasizes the importance of aligning cross-functional teams, integrating technology, and creating a culture of innovation and change. Takeaways Transformation vs. Change People-Centric Transformation Chapters 00:00 The Intersection of People, Techn...
The Concept of Powerful Imperfection - A Discussion with Kevin Voisin 15.06.2026 44:48
The conversation with Kevin Voisin delves into the role of a coach, the concept of powerful imperfection, the distinction between perfection and excellence, the importance of being coachable, and the impact of pretending. It also explores the challenge of telling the truth and the significance of perceived benefits versus goals. The conversation delves into the illusion of success, the importance...
AI in Healthcare: Julia Komissarchik discusses the Challenges and Opportunities 09.06.2026 29:02
Julia Komissarchik, CEO and co-founder of Glender, discusses the challenges and opportunities in AI and healthcare. She emphasizes the importance of access to data, de-identification of sensitive data, and the monetization of healthcare data. Julia also highlights the impact of AI on medical deserts, the adoption of AI in healthcare, and advancements in medical imaging. She stresses the human-cent...
Unlocking Business Growth: The Human and Data Connection - A conversation with Juli Baranik 05.06.2026 50:06
The conversation with Julie Baranik covers her career journey, the importance of learning and adapting, developing business systems, interpreting data and patterns, cultivating a healthy culture, leadership and accountability, building relationships and trust, empowering teams and mentorship, business analysis and insights, and efficiency and clarity in business meetings. The conversation delves i...
How Ownership and Culture Drive Scaling Success in Fast-Growth Companies with Nick Piscani 20.05.2026 30:18
The conversation with Nick Piscani, founder of MyExec, delves into the journey of financial leadership, scaling strategy, and the challenges of execution. Nick shares insights on the importance of purpose, culture, and cross-functional alignment in driving business success. Takeaways Purpose-Driven Entrepreneurship The Power of Culture and Trust Chapters 00:00 Keys to Entrepreneurial Success
How to Navigate the Messy Middle of Innovation: Insights from Kristen Gaylord 15.05.2026 5:06
The conversation explores the critical role of leaders in navigating change, providing context, managing friction, and fostering innovation within organizational structures. It delves into the behaviors and strategies required for effective leadership in times of change and innovation, emphasizing the importance of context, respect for differing viewpoints, and the balance between innovation and o...
The Future of Health Informatics: Bridging the Gap Between Data and Action with Laura-Maria Peltonen 14.05.2026 37:51
The conversation delves into the future of health informatics, challenges in health data usage, the role of AI tools in healthcare, and the importance of environmental sustainability in healthcare. The discussion highlights the gap between the promise of health data and its actual usage, the impact of AI tools in healthcare, and the need for environmental sustainability in healthcare systems. Take...
Bridging Innovation and Capital: Insights from Stan Glezer 14.05.2026 31:58
In this episode, Stan Glezer, Managing Director at Outcome Capital, shares insights on bridging innovation with capital and building companies that attract investment. He emphasizes the importance of translating innovation into value for investors and the critical role of operational experience in successful commercialization. The conversation also explores the significance of storytelling, valida...
Navigating the Intersection of Energy, AI, and Faith: Insights from Peter Snell 11.05.2026 40:17
The conversation with Peter Snell, CEO of PetroVybe, delves into the intersection of faith, leadership, and innovation in the energy industry. Peter shares insights on the role of faith in shaping leadership decisions, the challenges of monetizing energy and AI, and the need for honest conversation about hydrocarbons and renewable energy. He also emphasizes the concept of stewardship and the illus...
Understanding the Power of Ownership in Investing: Insights from Haren Bhakta 11.05.2026 31:08
The conversation with Haren Bhakta, the founder and CEO of the Inside Ownership Index, delves into the significance of ownership and leadership in company success and innovation. Aaron shares the challenges he faced in building the index and highlights the impact of ownership on company performance and innovation. The Inside Ownership Index and its performance are discussed, emphasizing the import...
Unlocking Customer Behavior in Life Sciences: 5 Key Strategies from Ray Abaskharon 07.05.2026 33:31
The conversation delves into the importance of understanding customer behavior, the challenges in product development, the role of AI in healthcare, and the impact of market research. Key takeaways include the significance of customer behavior and its impact on product success. Takeaways Customer behavior is key Understanding customer behavior is crucial for product success Chapters 00:00 Understa...
How to Escape the Operator Trap: 5 Strategies for Entrepreneurs with Mike DeJong 05.05.2026 38:23
In this conversation, Mike DeJong discusses the challenges of transitioning from an operator to a true owner, highlighting the common pitfalls of the 'Operator Trap.' He also delves into the concept of leadership archetypes and the various growth plateaus that businesses encounter. The conversation provides valuable insights for entrepreneurs and business owners looking to scale their operations a...
Trust, Intentionality, and Data-Driven Growth — The Key for Modern Agencies - Ari Pirutinsky 17.04.2026 41:03
The conversation covers a range of topics related to starting and growing a modern marketing agency, challenges of AI implementation, building trust and culture, adapting to client vocabulary, and advice for growth leaders. The speakers discuss the importance of understanding client goals, building a high-performance team, and being truthful and flexible in approach. They emphasize the need for a...
How to Achieve Financial Clarity: 4 Phases Every Founder Must Navigate - with Nate Littlewood 15.04.2026 30:49
The podcast episode features Nate Littlewood, a financial leader and founder, discussing financial leadership, scaling strategies, and the challenges faced by e-commerce and consumer products founders. Nate shares insights on the phases of founders' relationship with finances, the importance of strategic prioritization, and the impact of AI on marketing and customer acquisition. He emphasizes the...
The Future of Talent Management: a Discussion with Carlos Beatty, Jr. 09.04.2026 42:43
The conversation delves into the journey of Resumation, highlighting the shift from resume creation to capturing rich career stories. It also explores the role of AI in contextual search and the advisor relationship in the hiring process. The conversation covers the importance of adapting to changing needs, recognizing unique strengths, and the human element in AI. It also emphasizes the power of...
Strategy in the Age of AI: Differentiation Through Experience - featuring Gigi Kizhakkechethipuzha 06.04.2026 38:10
The conversation delves into Gigi's innovative approach to business, emphasizing the application of engineering principles to marketing, the creation of precise growth strategies, and the power of AI in decision-making. It also explores the fundamental role of strategy, the importance of speeding up the learning cycle, continuous improvement, rapid scaling, and accelerating business improvement. T...
Evolving POS Systems for Community Spaces - David Galindo Shares His Insights for Creating Value 24.03.2026 30:28
The conversation explores the leadership, growth, and consultative approach to dynamic merchant services and FinTech consulting. It delves into the impact of AI on business, the community-centric approach to business, and the importance of long-term relationship building. Key takeaways include the emphasis on a learning mindset and the value of a consultative approach in business. Takeaways Learni...
John Holcombe Answers Questions During Recent Book Launch 23.03.2026 4:47
The conversation covers a Q&A section, the power of diverse thought and cross-functional teams, inspiration for the project, feelings and topic for the book, and the process of creating the book. Key takeaways include the power of diverse thought and cross-functional teams, sharing insights from a bumpy journey of starting up new businesses, and the importance of clear thought and working with...
Andrew Chrostowski Shares his thoughts and experiences Monetizing Innovation 23.03.2026 37:02
Andrew Chrostowski shares insights on leadership, innovation, and the impact of technology on the workforce. He emphasizes the importance of people, systems, and discipline in driving value creation and success in the digital age. Takeaways People, Systems, Discipline Blue Collar Renaissance https://oggn.com/connected-workers/ https://www.linkedin.com/in/andrewchrostowski X: @ConnectedAndrew Chapt...
Angela Chamberlain: Agentic AI and the future of Small Business 17.03.2026 34:56
The conversation with Angela Chamberlain covers the strategic translation of business strategies into actionable systems and the adoption of agentic AI in small businesses. Angela emphasizes the importance of translating strategy into actionable systems to drive measurable impact. She also discusses the adoption of agentic AI tools to automate mundane tasks and improve productivity in small busine...
How to Transform Chemical Innovations into Market Success: Insights from Andrea Adamo 04.03.2026 35:07
The conversation with Andrea Adamo, the founder and CEO of Zaiput Flow Technologies, delves into the journey of innovation, from the inception of an idea to the challenges of building multiple product lines. Understanding customer needs, scaling, and the future of innovation are key themes explored in this insightful discussion. Takeaways Innovation must benefit people Understanding customer needs...
Sanjay Doddamani and Mark Selna: Revolutionizing Care Delivery with Advanced Technology 25.02.2026 33:04
The conversation delves into the intersection of health data and innovation, exploring the challenges and insights in AI implementation in healthcare. It also covers the founding of Guide Health and its mission to drive healthcare affordability, as well as the impact of technology and AI on healthcare delivery and quality improvement. Takeaways Healthcare Innovation AI in Healthcare Chapters 00:00...
Zachary Ducharme: The Long Road to Overnight Success 23.02.2026 25:57
The conversation with Zachary Ducharme covers his journey, challenges, and strategies in leadership, strategic partnerships, scaling, AI integration, cross-functional collaboration, and core values. Zachary shares insights on adapting to leadership roles, building strategic partnerships, challenges in scaling, and the importance of core values and culture in the organization. Takeaways Leadership...
Revolutionizing Healthcare: Dr. Brandon Colby on the Future of Genomics and Personalized Medicine 19.02.2026 24:06
Dr. Brandon Colby, a medical geneticist and CEO of sequencing.com, shares his journey from a rare genetic condition to pioneering whole genome sequencing. The conversation explores the significance of whole genome sequencing, AI integration in preventative medicine, and the impact on healthcare accessibility. Dr. Colby also discusses leadership challenges, insights for health innovators, and the i...
Transforming Ideas into Impact: Insights from Kristine Vlahos Gagne on Innovation and Leadership 18.02.2026 44:15
The conversation delves into the importance of human-centered leadership, the innovation process, and the behavioral and emotional aspects of change. It explores the impact of AI on cognitive load, the significance of data connectivity, and the value of systems thinking and lean innovation. The discussion emphasizes the need for a robust problem-solving toolkit and the role of a human-centered app...
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