Heather D. Couture

Impact AI

Learn how to build a mission-driven machine learning company from the innovators and entrepreneurs who are leading the way. A weekly show about the intersection of ML and business – particularly startups. We discuss the challenges and best practices for working with data, mitigating bias, dealing with regulatory processes, collaborating across disciplines, recruiting and onboarding, maximizing impact, and more.

Author

Heather D. Couture

Category

Technology

Podcast website

pixelscientia.com

Latest episode

Jun 16, 2025

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Episodes

Impact AI Update: Summer Break & Webinar Resources 16.06.2025

I will be taking a brief hiatus for the next three months. I’m going to be using this time to step back, reflect, and rework the format of the show to bring you even more valuable insights and engaging conversations. I’m looking forward to returning in the fall with fresh episodes, new guests, and even deeper dives into the challenges and opportunities shaping mission-driven machine learning-power...

Advancing Breast Cancer Screening with Nico Karssemeijer from ScreenPoint Medical 02.06.2025

What role can artificial intelligence play in detecting breast cancer earlier, when it's most treatable? In this episode of Impact AI, we hear from Nico Karssemeijer, Chief Science Officer of ScreenPoint Medical, about how his team is using AI to transform breast cancer screening. Drawing on more than four decades of experience in medical imaging, Nico shares how ScreenPoint’s AI tools assist radi...

Radiology Tools for Precision Medicine with Ángel Alberich-Bayarri from Quibim 19.05.2025

How can we harness medical imaging and artificial intelligence to shift healthcare from reactive to predictive? In this episode, I sit down with Ángel Alberich-Bayarri to discuss how artificial intelligence is revolutionizing radiology and precision medicine. Ángel is the CEO of Quibim, a company recognized globally for its AI-powered tools that turn radiological scans into predictive biomarkers,...

Simulating Clinical Trials with Orr Inbarr from Quant Health 05.05.2025

Drug development is notoriously time-consuming and expensive, but what if we could simulate clinical trials before they even begin? Orr Inbar, Co-Founder and CEO of QuantHealth, joins me to explore how his team is doing just that. By simulating trials with AI-native models, QuantHealth helps pharmaceutical companies make better decisions about how to design trials and test drugs. Orr shares how Qu...

Early Wildfire Detection with Shahab Bahrami from SenseNet 21.04.2025

The recent destruction of the Pacific Palisades in Los Angeles was a brutal reminder of why we need robust early wildfire detection systems. Joining me today is Shahab Bahrami, the co-founder and CTO at SenseNet – a company that provides advanced AI-powered cameras and sensors to protect communities and valuable assets against wildfires. Shahab is passionate about using interdisciplinary research...

Foundation Model Series: Empowering Drug Discovery with Rick Schneider from Helical 07.04.2025

AI is transforming drug discovery by making biological data more accessible and actionable, bridging the gap between complex sequencing data and real-world therapeutic breakthroughs. As Rick Schneider puts it, it's all about leveraging powerful models to “build use cases that matter and bring value.” In this episode of Impact AI, we hear from the CEO and Co-founder of Helical to find out how bio-f...

Streamlining Radiology with Junaid Kalia from NeuroCareAI 24.03.2025

AI tools for healthcare are becoming more prevalent than ever before, and today, we explore how this could help usher in a future of democratized healthcare for all. I am joined by the neurocritical stroke and epilepsy specialist Junaid Kalia, MD, founder of NeuroCareAI – an innovative enterprise utilizing artificial intelligence solutions to enhance health outcomes and efficiency. Junaid begins w...

Foundation Model Series: Advancing Precision Medicine in Radiology with Paul Hérent from Raidium 03.03.2025

Radiologists face a growing demand for imaging analysis, yet existing AI tools remain fragmented, each solving only a small part of the workflow. Today, we continue our series on domain-specific foundation models with Paul Hérent, Co-Founder and CEO of Raidium. He joins us to discuss how foundation models could revolutionize radiology by providing a single AI-powered solution for multiple imaging...

Foundation Model Series: Advancing Endoscopy with Matt Schwartz from Virgo 24.02.2025

What if a routine endoscopy could do more than just detect disease by actually predicting treatment outcomes and revolutionizing precision medicine? In this episode of Impact AI, Matt Schwartz, CEO and Co-Founder of endoscopy video management and AI analysis platform Virgo, discusses how AI and machine learning are transforming endoscopy. Tuning in, you’ll learn how Virgo’s foundation model, EndoD...

Foundation Model Series: Transforming Biology with Zelda Mariet from Bioptimus 17.02.2025

Zelda Mariet, Co-Founder and Principal Research Scientist at Bioptimus, joins me to continue our series of conversations on the vast possibilities and diverse applications of foundation models. Today’s discussion focuses on how foundation models are transforming biology. Zelda shares insights into Bioptimus’ work and why it’s so critical in this field. She breaks down the three core components inv...

Foundation Model Series: Democratizing Time Series Data Analysis with Max Mergenthaler Canseco from Nixtla 10.02.2025

What if the hidden patterns of time series data could be unlocked to predict the future with remarkable accuracy? In this episode of Impact AI, I sit down with Max Mergenthaler Canseco to discuss democratizing time series data analysis through the development of foundation models. Max is the CEO and co-founder of Nixtla, a company specializing in time series research and deployment, aiming to demo...

Foundation Model Series: Harnessing Multimodal Data to Advance Immunotherapies with Ron Alfa from Noetik 03.02.2025

In this episode, I'm joined by Ron Alfa, Co-Founder and CEO of Noetik, to discuss the groundbreaking role of foundation models in advancing cancer immunotherapy. Together, we explore why these models are essential to his work, what it takes to build a model that understands biology, and how Noetik is creating and sourcing their datasets. Ron also shares insights on scaling and training these model...

Foundation Model Series: Accelerating Pathology Model Development Using Embeddings with Julianna Ianni from Proscia 27.01.2025

How can foundation models accelerate breakthroughs in precision medicine? In today’s episode of Impact AI, we explore this question with returning guest, Julianna Ianni, Vice President of AI Research and Development at Proscia, a company revolutionizing pathology through cutting-edge technology. Join us as we explore how their platform, Concentriq, and its new Embeddings feature are transforming A...

Actionable Soil Insights with Benjamin De Leener from ChrysaLabs 06.01.2025

With farmers sometimes waiting weeks for lab results to make critical decisions, Benjamin De Leener, Co-Founder and Chief Science Officer of ChrysaLabs, sought to transform the future of soil health. ChrysaLabs has developed a groundbreaking handheld, AI-powered probe that delivers fast field-ready insights into soil properties like pH, nutrients, and organic matter. In this episode of Impact AI,...

Advancing Therapies for Immune Diseases with Kfir Schreiber from DeepCure 16.12.2024

Can AI cure autoimmune diseases? This episode of Impact AI dives into the groundbreaking work of DeepCure, where artificial intelligence meets medicinal chemistry to tackle some of healthcare's most stubborn challenges. Co-founder and CEO Kfir Schreiber shares how his team uses advanced machine learning tools, physics simulations, and human expertise to design the next generation of small molecule...

Unlocking Unstructured Health Data with David Sontag from Layer Health 09.12.2024

What if we could unlock the hidden potential of unstructured health data to improve patient outcomes? In this episode, I sit down with David Sontag, co-founder and CEO of Layer Health, to discuss the transformative role of AI in healthcare. David, an MIT professor (on leave) and leading machine learning researcher, delves into how Layer Health addresses one of healthcare’s most persistent challeng...

Discovering Protein Drug Candidates with Hanadie Yousef from Juvena Therapeutics 25.11.2024

How can advancements in biotechnology and machine learning lead to revolutionary treatments for age-related diseases? In this episode, I speak with Hanadie Yousef, CEO and Co-Founder of Juvena Therapeutics, to discuss her work on protein-based therapeutics. Hanadie, a neurobiologist specializing in aging and tissue degeneration, has pioneered research at Juvena to identify regenerative proteins th...

Real-World Evidence for Healthcare with Brigham Hyde from Atropos Health 18.11.2024

To succeed at an AI startup, you have to be able to show your work and its value. During this episode, I am joined by Brigham Hyde, Co-Founder and CEO of Atropos Health, to talk about his app that gathers real-world evidence for healthcare. He is an entrepreneur, operator, and investor who is deeply immersed in the potential of data and AI. Join us as he shares his journey to creating Atropos Heal...

De-Risking Drug Translation with Jo Varshney from VeriSIM Life 11.11.2024

As machine learning becomes increasingly widespread, AI holds the potential to revolutionize drug development, making it faster, safer, and more affordable than ever. In this episode, I'm joined by Jo Varshney, Founder and CEO of VeriSIM Life, to explore how her company is transforming drug translation through hybrid AI. With her unique blend of expertise as a veterinarian and computer scientist,...

Decoding the Immune System for Drug Discovery with Noam Solomon from Immunai 04.11.2024

Today’s guest believes that decoding the immune system is at the heart of improving drug efficacy. He is currently focused on this effort as the CEO and Co-founder of Immunai – a company that is building an AI model of the immune system to facilitate the development of next-generation immunomodulatory therapeutics. Noam Solomon begins our conversation by detailing his professional history and how...

Foundation Model Series: Accelerating Radiology with Robert Bakos from HOPPR 28.10.2024

Imagine a world where radiology backlogs are a thing of the past, and AI seamlessly augments the expertise of radiologists. Today, I'm joined by Robert Bakos, Co-Founder and CTO of HOPPR, to discuss how his company is bringing this vision to life. HOPPR is pioneering foundation models for medical imaging that have the potential to transform healthcare. With access to over 15 million diverse imagin...

Optimizing Data Center Operations with Vedavyas Panneershelvam from Phaidra 21.10.2024

What are the unique challenges of operating mission-critical facilities, and how can reinforcement learning be applied to optimize data center operations? In this episode, I sit down with Vedavyas Panneershelvam, CTO and co-founder of Phaidra, to discuss how their cutting-edge AI technology is transforming the efficiency and reliability of data centers. Phaidra is an AI company that specializes in...

Structuring Medical Text with Tim O'Connell from Emtelligent 14.10.2024

What if AI could unlock the potential of healthcare’s vast, unstructured data? In this episode, Tim O'Connell, Co-Founder and CEO of Emtelligent, explains how his company is bridging the gap between messy medical data and usable insights with AI-powered solutions. Drawing from his background in both engineering and radiology, Tim discusses how he saw firsthand the inefficiencies caused by disorgan...

Foundation Model Series: Enabling Digital Pathology Workflows with Dmitry Nechaev from HistAI 07.10.2024

What happens when you combine AI with digital pathology? In this episode, Dmitry Nechaev, Chief AI Scientist and co-founder of HistAI, joins me to discuss the complexity of building foundation models specifically for digital pathology. Dmitry has a strong background in machine learning and experience in high-resolution image analysis. At HistAI, he leads the development of cutting-edge AI models t...

Foundation Model Series: Creating Small Molecules for Drug Discovery with Jason Rolfe from Variational AI 30.09.2024

Building on the trends in language processing, domain-specific foundation models are unlocking new possibilities. In the realm of drug discovery, Jason Rolfe is spearheading innovation at the intersection of AI and pharmaceuticals. As the Co-Founder and CTO of Variational AI, Jason leads a platform designed to generate novel small molecule structures that accelerate drug development. In this episo...

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