Healthy Dialogue

Two new trials published in JAMA evaluate the efficacy of periprocedural intra-arterial thrombolytics after successful endovascular thrombectomy for patients with acute ischemic stroke. Diederik Dippel, MD, PhD, of Erasmus University Medical Center discusses this and more with JAMA Deputy Editor Christopher C. Muth, MD. Related Content: Intra-Arterial Thrombolytics During Thrombectomy for Ischemic...

Private equity acquisitions of health care facilities have rapidly increased over the past decade. However, little is known about the effects of these acquisitions on patient experience. Author Rishi K. Wadhera, MD, MPP, MPhil, of Harvard Medical School discusses this topic with JAMA Associate Editor Karen Joynt Maddox, MD, MPH. Related Content: Changes in Patient Care Experience After Private Equ...

Certain CD4+ T-cell subtypes play a role in asthma. Characterizing asthma endotypes in diverse groups is important to help develop effective therapies for youth with asthma. Author Juan C. Celedon, MD, DrPH, University of Pittsburgh, Department of Pediatrics, discusses this and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Transcriptomic Profiles in Nasal Epithelium and...

Most Medicare Advantage (MA) plans offer dental care coverage as a supplemental benefit. However,few beneficiaries are enrolled in an MA plan that provides comprehensive dental benefits. Lisa Simon, MD, DMD, discusses this and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Availability of Dental Benefits Within Medicare Advantage Plans by Enrollment and County

Long COVID is now defined as a heterogeneous, infection-associated chronic condition present for at least 3 months after SARS-CoV-2 infection. Author Leora Horwitz, MD, MHS, of NYU Grossman School of Medicine joins JAMA Executive Editor Gregory Curfman, MD, to discuss the JAMA article "2024 Update of the RECOVER-Adult Long COVID Research Index." Related Content: 2024 Update of the RECOVER-Adult Lo...

Triple-negative breast cancer accounts for around 15% of breast cancers. Zhi-Ming Shao, MD, of Fudon University, joins JAMA Oncology Editor in Chief and JAMA Deputy Editor Nora Disis, MD, to discuss "Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients with Early or Locally Advanced Triple-Negative Breast Cancer: The CamRelief Randomized Clinical Trial." Re...

New antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection. Author Rajesh T. Gandhi, MD, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss these new approaches for HIV. Related Content: Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel Adv...

A new JAMA study examines the association between severe maternal morbidity in a first birth and the probability of a subsequent birth. Authors Neda Razaz, PhD, and Eleni Tsamantioti, MD, MMedSc, both from the Karolinska Institute in Sweden, discuss this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH. Related Content: Association of Severe Maternal Morbidity With Subsequent Birth Se...

Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic's Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran produced more than 80% reductions in time-averaged lipoprotein(a) concentration. Related Content: Zerlasiran—A Small-Interfering RNA Targeting Lipoprotein(a)

Preterm birth is the greatest cause of neonatal mortality and morbidity, with infants born extremely preterm at highest risk. Author Brett J. Manley, PhD, the Royal Women's Hospital, Melbourne, Australia, discusses a new study of the effect of intratracheal corticosteroid administration on survival free of bronchopulmonary dysplasia in preterm infants, with JAMA Deputy Editor Tracy A. Lieu, MD, MP...

Preventing obesity in early childhood is challenging for clinicians and families. Authors Eliana M. Perrin, MD, MPH, of Johns Hopkins University, and William J. Heerman, MD, MPH, of Vanderbilt University, join JAMA Deputy Editor Tracy Lieu, MD, to discuss "A Digital Health Behavior Intervention to Prevent Childhood Obesity: The Greenlight Plus Randomized Clinical Trial." Related Content: A Digital...

A new study published in JAMA found that drug-related supply chain issue reports were 40% less likely to result in meaningful drug shortages in Canada compared with the US. Authors Kate Suda, PharmD, MS, of University of Pittsburgh School of Medicine, and Mina Tadrous, PharmD, PhD, of University of Toronto, discuss this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS. Related Content: Dif...

In the US, childbirth typically occurs in hospitals or accredited birth centers. President of the American College of Obstetricians and Gynecologists Stella Marie Dantas, MD, speaks with JAMA Deputy Editor Linda Brubaker, MD, MS, about newly proposed advanced birth centers that would permit higher-risk births, with concerns for patient safety and rural obstetric care access. Related Content: Advan...

The Declaration of Helsinki originated in 1964, developed by the World Medical Association (WMA). Process Chair Jack S. Resneck Jr, MD, discusses the 2024 updates to the Declaration of Helsinki with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Revisions to the Declaration of Helsinki on Its 60th Anniversary World Medical Association Declaration of Helsinki Making th...

Transfusion strategy for patients with acute brain injury, telehealth care, acute kidney injury after cardiac surgery, and weaning ventilatory support are the topics of 4 trials published in JAMA and presented at the 2024 European Society of Intensive Care Medicine meeting. JAMA Associate Editor Christopher Seymour, MD, MSc, joins Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss....

Gastric cancer is a leading cause of cancer death globally. Chronic H pylori infection is the primary cause of gastric cancer, responsible for at least 80% of the new cases. Constanza Camargo, PhD, of the National Cancer Institute joins JAMA Associate Editor John M. Inadomi, MD, to discuss co-testing with FIT and H pylori stool antigen to help prevent gastric cancer. Related Content: Fecal Immunoc...

Fever is associated with worse outcomes in patients with stroke, but whether preventing fever improves outcomes is unclear. David M. Greer, MD, MA, speaks with JAMA Associate Editor Jeffrey L. Saver, MD, about fever prevention in patients with acute stroke and its impact on functional outcomes. Related Content: Fever Prevention in Patients With Acute Vascular Brain Injury Feasibility of Fever Prev...

The 2024 Lasker–DeBakey Clinical Medical Research Award has been presented for the discovery of GLP-1 and its application to the treatment of obesity. Lasker winner Svetlana Mojsov, PhD, discusses her role in this innovative discovery and more with JAMA Senior Editor Anne Rentoumis Cappola, MD, ScM. Related Content: Chemistry Matters—From a Putative Peptide to Effective Treatments for Diabetes and...

Palliative care is an essential component to high-quality care for patients with cancer. How can access to palliative care be expanded? Eduardo Bruera, MD, from MD Anderson Cancer Center speaks with JAMA Editor in Chief Kirsten Bibbins-Domingo about 2 new trials in JAMA that address access to care and what more it will take for executives, insurers, and regulators to support palliative care progra...

A new trial assessed whether balloon angioplasty plus aggressive medical management was superior to aggressive medical management alone for patients with symptomatic intracranial atherosclerotic stenosis. Author Zhongrong Miao, MD, PhD, from Beijing Tiantan Hospital, discusses the BASIS randomized clinical trial with JAMA Deputy Editor Christopher C. Muth, MD. Related Content: Balloon Angioplasty...

The abating COVID-19 pandemic brings attention to rising mortality rates from non-COVID causes in the US, a trend that predates the COVID-19 pandemic. Viewpoint author Steven H. Woolf, MD, MPH, discusses this and more with JAMA Executive Editor Gregory Curfman, MD. Related Content: Increasing Mortality Rates in the US, but Not From COVID-19

Nonhormonal treatments for menopausal vasomotor symptoms may benefit symptomatic patients who cannot take or prefer to avoid systemic hormones. Author JoAnn V. Pinkerton, MD, MSCP, discusses the efficacy and safety of elinzanetant for the treatment of moderate to severe vasomotor symptoms associated with menopause with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content: Elinzanetant for th...

To address the need to characterize long COVID in children and adolescents, the National Institutes of Health funded a pediatric program in the Researching COVID to Enhance Recovery (RECOVER) Initiative. Editorialist Suchitra Rao, MBBS, MSCS, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, discusses this and more with JAMA Senior Editor Tracy A. Lieu, MD, MPH. R...

A new study looks at uterus transplant to determine if it is safe, feasible, and results in births of healthy infants. Editorialist Emily Jungheim, MD, MSCI, Northwestern University, discusses this innovative treatment with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content: Uterus Transplant—The Frontier of Innovative Fertility Treatment Uterus Transplant in Women With Absolute Uterine-Fa...

Ten percent of US adolescents use e-cigarettes, and many want to quit. However, evidence on the effectiveness of vaping cessation interventions is lacking. Amanda L. Graham, PhD, of the Truth Initiative discusses with JAMA Senior Editor Tracy Lieu, MD, MPH, how a tailored, interactive text message intervention increased vaping cessation among adolescents recruited via social media channels. Relate...