Gladstone Audio News

Gladstone scientists developed a new tool to trace how the brain clears “waste,” uncovering surprising new biology about how it keeps itself healthy. Read the study, published in  Cell. Read this story on gladstone.org.

Thirty years after discovering a gene, Shinya Yamanaka and his team show that it’s essential for keeping intestinal stem cells stable, offering insight into how tissues repair themselves. Read this story on our website. 

A new study upends long-held view about how DNA is stored, explaining how subtle shifts in gene activity contribute to cancer, aging, and other complex diseases. Read this story on gladstone.org.

Scientists at Gladstone expanded their retron-based genome editing technology beyond E. coli, showing it works in 15 diverse bacterial species. Read this article on gladstone.org.  Read the scientific publication. 

A team of scientists at Gladstone and UCSF created a new genetic roadmap that reveals hundreds of hidden players in HIV infection, including two proteins that stop HIV in its tracks. Read this story on gladstone.org. Read the scientific publication. 

New findings on the APOE4 gene variant point to a potential therapeutic target for Alzheimer’s disease.  Read this story on gladstone.org. Read the scientific publication. 

Trained on data spanning the human lifespan, the tool developed at Gladstone can predict genes associated with aging and age-related diseases. Details appear in new study led by Christina Theodoris, MD, PhD, whose team developed the model. Read this story on gladstone.org. Read the preprint. 

A team of Gladstone scientists, led by Nadia Roan, uncovered a new path toward life without daily HIV pills, suggesting that a common diabetes pill could help achieve long-term remission. Read this story on gladstone.org. Read the scientific publication. 

A team of scientists, led by Gladstone Investigator Nadia Roan, developed a novel tool, named HIV-seq, that could uncover new opportunities for treating HIV. Read the scientific publication Read this story on gladstone.org.

A new framework that matches vitamins with genetic diseases helped uncover that high-dose vitamin B3 can dramatically extend survival in mice with NAXD deficiency. Read this story on gladstone.org Read the scientific publication

A team of scientists discovered that red blood cells act as hidden glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates and pointing toward new treatments. Read this article on gladstone.org. Read the scientific publication. 

In a new study featured in Nature Cardiovascular Research, Gladstone scientists identified a cellular boundary that guides heart development and revealed how disrupting it can lead to holes in the heart’s wall. Read the scientific publication Read the article on Gladstone.org

A team of scientists at Gladstone developed a new gene editing method and showed that only a few variations of the therapy could treat the majority of patients with Charcot-Marie-Tooth disease. Read this article on gladstone.org Read the scientific publication. 

Gladstone Institutes researcher Alex Marson and his collaborators at Stanford University developed a genomic mapping technique that helps close the gap in understanding why certain genetic variants are tied to disease. Read this story on gladstone.org . Read the scientific publication. 

A new study by scientists from Gladstone, the Innovative Genomics Institute, and UC Berkeley could influence how gene therapies are designed for many genetic diseases . Read the scientific publication Read this article on gladstone.org

Gladstone Investigator Ken Nakamura led a study that strengthens the links between energy breakdown in cells and the onset of Parkinson’s, potentially illuminating new paths for treatment. Read the scientific publication Read this article on Gladstone.org

Scientists at Gladstone Institutes and UC San Francisco learn to fine-tune a gene that is centrally involved in regulating the immune system, offering potential clues for future autoimmunity and cancer treatments. Read the scientific publication Read the article on Gladstone.org

A powerful scientific platform opens new possibilities for treating cancer, autoimmune diseases, and other conditions in which reprogrammed T cells could provide a benefit to patients. Read this article on gladstone.org. Read the scientific publication. 

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. This is an audio version of the article, "Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome," published on Gladstone.org.   Read the article on our website . Read the scientific publication.

A discovery about the consequence of neuron overactivity could lead to new methods of treating or preventing Parkinson’s disease. This is an audio version of the article, "Overworked Brain Cells May Burn Out in Parkinson’s Disease."  Read the article on our website Read the scientific publication

Listen to this in-depth explainer about different types of vaccines and what happens in the body after vaccination. Read the story on our website.

Gladstone scientists, led by Andrew Yang, PhD, show that known genetic risk factors for neurological diseases act in the brain’s blood vessels and immune cells, revealing new targets for therapies. This is an audio version of the article, "Blood Vessels and Immune Cells Drive Risk for Alzheimer’s and Stroke," published on gladstone.org on July 28, 2025. This episode is narrated by an AI-...

A new study from the Roan lab found strong immune defenses in pregnant and lactating women, with key benefits that could guide future vaccine design. Read more about the study on our website. Read the scientific publication. This is an audio version of the article "Pregnancy, Lactation Shape Immune Response to COVID-19 Vaccine and Infection." This article was read by an AI-voice for acce...

From discovering therapies that can repair the brain after stroke to using machine learning to detect early signs of cognitive decline, our researchers are at the forefront of neurological research. In honor of World Brain Day, discover some of Gladstone’s latest breakthroughs. Read this article on our website. Learn more about each of these topics: Stem Cell Therapy Jumpstarts Brain Recovery Afte...

A new study has identified FDA-approved cancer drugs that reverse the gene expression signatures associated with Alzheimer’s. This is an audio version of the article, "Combination of Two Cancer Drugs May Work Against Alzheimer’s," published on gladstone.org on July 21, 2025. This episode is narrated by an AI-voice.  More Read this article on our website. Read the scientific publication.