Fortune 500: Titans and Disruptors of Industry

For more than 100 years, TIAA has helped millions of Americans — from educators to healthcare workers to public servants — turn their savings into guaranteed income they cannot outlive. Today, the company is expanding beyond its traditional 403(b) roots, pioneering lifetime income solutions inside 401(k) plans and using AI to better protect and serve participants. In this episode, Fortune’s Editor...

For over 40 years, Qualcomm technology has powered some of the world’s most transformational technological advancements. Today, the company is moving beyond smartphones, building a future with wearable AI, humanoid robots, and a 6G cellular network. In this episode, Fortune’s Editor-in-Chief Alyson Shontell speaks with Qualcomm’s President and CEO Cristiano Amon to discuss the company’s commitment...

From one of the largest bankruptcies in U.S. history to leading the industry in market capitalization and premium customer satisfaction, Delta Air Lines has rewritten the business of flying in the last two decades.  In this episode, Fortune's Editor-in-Chief Alyson Shontell sits down with CEO Ed Bastian at Delta’s Atlanta headquarters to discuss the strategic maneuvers behind the airline’s resurge...

What if AI made your paycheck optional? Vinod Khosla, one of the world's greatest venture capitalists and an early backer of AI, believes the technology will take over 80% of labor, freeing humans to live on passion instead. His track record backs up the boldness, as early bets on OpenAI, DoorDash, Instacart, and Square have made him one of the most consequential investors of our time. In this epi...

Google DeepMind founder and CEO Sir Demis Hassabis is a master chess player, a recipient of the Nobel Prize in Chemistry, and - as of 2024 - a Knight. Today, as a leader within Google’s booming AI team, Hassabis wants to make AI the “engine” driving the entire company. In this episode of Fortune 500: Titans and Disruptors of Industry, Fortune’s Editor-in-Chief Alyson Shontell sits down with Hassab...

Dr. Albert Bourla became Pfizer’s CEO months before the COVID-19 pandemic took hold of the US. Under his leadership, Pfizer manufactured 3 billion doses of the first FDA-approved vaccine in the first year, which led to record-breaking earnings. Yet over the past few years, post-pandemic sales slumps, patent cliffs and vaccine skepticism have driven down Pfizer’s earnings. In this episode of Fortun...

It’s been one year since Vice President Kamala Harris and then-Democratic nominee was coming down to her final days of the 2024 presidential campaign against Donald Trump. She spent 107 days on the road in a bid to earn their vote, but it wasn’t enough. Almost one year later, she’s had time to reflect. In a wide-ranging conversation at Fortune’s Most Powerful Women summit, Harris joined Fortune’s...

JPMorgan Chase CEO Jamie Dimon has led the nation's largest financial institution through times of disruption for two decades. As Dimon navigates today's world of generative AI, President Trump's policies, and the effects on the global economy, Dimon sat down with Fortune's Editor-in-Chief, Alyson Shontell, to discuss these topics at the Most Powerful Women Summit in Washington, D.C. Dimon shares...

Ramp CEO Eric Glyman has helped build one of fintech’s fastest-growing startups — hitting $1 billion in annualized revenue, serving 45,000 businesses, and soaring to a $22.5 billion valuation in just 2,367 days. In this episode of Fortune 500: Titans and Disruptors of Industry, he sits down with Fortune’s Editor-in-Chief Alyson Shontell to break down Ramp’s meteoric rise, the business model flippi...

AI is rewriting the rules of business — and Accenture CEO Julie Sweet says reinvention is the only way Fortune 500s will survive. In the debut episode of Fortune 500: Titans and Disruptors of Industry, Sweet sits down with Fortune’s Editor-in-Chief Alyson Shontell to reveal how she’s nearly doubled Accenture’s value, grown its workforce to 770,000, and kept the company thriving through disruption....