#ExpertAnswers - an InsideScientific Podcast

Ana Briones discusses her research on the effects and potential therapeutic targets of excessive inflammation and vascular damage in hypertension.

Licy Yanes Cardozo expands on her research exploring the role of androgens on cardiovascular physiology in cis and transgender patients.

Aaron Phillips discusses questions from a recent webinar on his research involving neural hemodynamic control in pre-clinical and clinical models.

Matthew Sparks discusses his latest findings on a system of vascular-epithelial in the kidney that regulates pressure natriuresis.

Valeria Fumagalli and Nancy Kouassi discuss the Syrian golden hamster model of COVID-19, and present a new inhalation exposure-based mouse model using aerosolized SARS-CoV-2. 

Dr. Bonnie Lun from Fortis Life Sciences discusses applications and advantages of using nanobodies for diagnostic and therapeutic research, and highlights Fortis/Abcore's single-domain antibody discovery services.

Peter Ansell and Dr. Marian Navratil discuss the use of novel RNA-based gene expression profiling technologies for clinical and preclinical oncology research.

Louise Naylor focuses on the benefits of exercise to optimize and maintain the cardiovascular system.

Michael Long and Kari Hoffman investigate the neural mechanisms of learning, memory, and behavior using high-density silicon probes from Diagnostic Biochips in small and large animals.

Guto Montezano discusses the role of endothelial inflammation and ACE2 biology in COVID-19 infections and the resulting long-term effects.

Bastiaan Bijl and Dylan Mooijman provide an introduction to single-cell sequencing including potential applications with user cases.

Edward LeCluyse and Paul Gallant discuss their novel all-human hepatic triculture system including its benefits and applications.

Franck Lebrin and Denis Vivien discuss their work on microvascular and functional ultrasound imaging in stroke and neurovascular diseases.

Yuning Chen discusses strategies involved in recombinant antibody production and introduces a novel antibody expression platform to facilitate antibody library generation.

Ashley Walker discusses her research on the vascular contributions to late-onset Alzheimer’s disease.

Marta Walasek and Danielle Nguyen Truong provide tips and tricks to lock down effective genome editing conditions for CD34+ cells, methods to evaluate genome editing efficiency, and optimal culture conditions to maintain Hematopoeitic stem cell function and long-term editing effects.

Guozheng Shao and Anna Scott discuss the development of an osmotic membrane for use in a portable hemodialysis device and its validation using amino acid analysis to quantify urea removal.

Christopher West discusses the cardiovascular and autonomic changes that occur following spinal cord injury. 

Jason Rogers and De Wet Wolmarans discuss two research protocols for tracking, quantifying, and analyzing behaviors in rodent models.

Martin Slater discusses common challenges in molecule design and how they can be overcome with computational chemistry methods.

Louise Parr-Brownlie and Conor Underwood discuss the impact of acute optogenetic stimulation for the treatment of Parkinson's disease in a rat model.

Joe Soughayer and Adam Veteto discuss excitation-contraction coupling in cardiomyocytes and the tools used to characterize this.

Bin Xie discusses the current immuno-oncology drug development landscape, different humanized mouse models available for drug testing, and the investigation of potential mechanisms via imaging mass cytometry.

Raul Andero answers questions from a webinar where he presented research on sex-dependent differences in the consolidation of fear memory in a rodent model.

Anuj Kalsy and Robert Snyder showcase Precision for Medicine's variant-rich biobank, including discussion on biospecimen types, applications, screening methods, and support for companion diagnostic development.