Enrico Mayor Podcast

Rolf Potts — Author of Vagabonding — The real upgrade isn’t making more money—it’s becoming “time rich” (and travel is the fastest way to learn it) In this uncut conversation we discuss: • Why watching his grandparents age taught Rolf that time—not money—is the real currency • How “traveling in the local economy” leads to deeper experiences (and costs far less) • The #1 mistake entrepreneurs make...

Jens Juul Holst — Discoverer of GLP-1 & “Godfather of Ozempic” — The scientist behind Ozempic explains why these drugs work so well, what the real risks are, and why they may reshape how the world fights obesity. In this uncut conversation we discuss: • How GLP-1 was discovered and why it first mattered for diabetes, not weight loss • The simple science behind Ozempic, Wegovy, and Mounjaro in...

Stephanie Seneff — MIT research scientist — Why a “simple” herbicide may be quietly reshaping our microbiome, metabolism, and chronic disease risk. In this uncut conversation we discuss: • How Stephanie pivoted from early spoken-language AI at MIT to studying autism and environmental toxins • Glyphosate explained simply: a glycine “lookalike” and what that could mean for protein function • Why “no...

Richard Miller — Founder of iRest Yoga Nidra — The surprising shift that changes everything: start your meditation with what’s already “right” in you (indestructible well-being), then use it to meet stress, trauma, pain, and life. In this uncut conversation we discuss: • What iRest is (and why the U.S. military helped popularize it for PTSD) • The 10-step iRest protocol: intention, body sensing, b...

Sarah McKay — Neuroscientist — The biggest “female brain differences” might come from society, not biology—and pregnancy literally rewires the brain for motherhood. In this uncut conversation we discuss: • Why female brains look *more similar* to male brains in more gender-equal countries • The 2016 pregnancy study showing massive brain reorganization for social cognition • “Baby brain” explained:...

Christopher Germer — Clinical Psychologist — The fastest way to calm anxiety isn’t “thinking positive”—it’s shifting your body from threat to care with self-compassion. In this uncut conversation we discuss: • How loving-kindness ended Chris’ 20-year public speaking anxiety • Why self-compassion works physiologically (vagus nerve, HRV, cortisol)  • The 3 components of self-compassion: mindfulness,...

Scott Kelly — NASA Astronaut — A year in orbit doesn’t just change your body—it rewires how you see Earth, risk, politics, and what actually matters. In this uncut conversation we discuss: • Why the “hardest part of Mars” isn’t rocket science—it’s political science • The real odds of dying on launch (and why astronauts still get on the rocket) • What daily life on the ISS actually feels like: sche...

Esther Gokhale — Posture Coach — Why “sit up straight” may be making your back pain worse, and the simple posture shifts that can reshape your spine and relieve pain. In this uncut conversation we discuss: • Why modern back pain starts with lost posture habits, bad furniture, and even baby seats • The difference between a C-spine, S-spine, and Esther’s pain-saving J-spine • Why sitting isn’t the e...

Roger Berkowitz — Political Theory Professor — Why today’s “left vs right” chaos is really a class revolt of the “virtuals” vs the “reals” (and how Arendt helps us rebuild common sense) In this uncut conversation we discuss: • The new political “revolution”: virtual elites vs hands-on “real” life—and why resentment is exploding • How the retreat of everyday citizens from politics helped create tod...

Erwan Le Corre — Natural movement pioneer — The real “fitness upgrade” isn’t another workout plan—it’s learning to shape the experience of yourself in every single moment. In this uncut conversation we discuss: • Why modern comfort (screens, chairs, indoor life) quietly drains both body and mind • Simple “anti-sitting” upgrades: standing desks, dynamic sitting, and movement micro-breaks • Discipli...

Nicolas Huber — Swiss Olympic Snowboarder — He tested positive for COVID the moment he landed at the Olympics in China… then fought his way out of isolation just in time to compete. In this uncut conversation we discuss: • Getting “ported” to a quarantine hotel in Beijing and still making it to Olympic training + competition • The mental “zone” at the start gate: breathwork, mantras, and committin...

Francesco D’Alessio — Keep Productive Founder — The biggest productivity upgrade isn’t a new app—it’s cutting the noise, locking in your principles, and using tools only as a thin layer on top. In this uncut conversation we discuss: • What Francesco would do if every productivity app disappeared overnight (and why it’s freeing) • The Bento Method: packing your day into “large/medium/small” tasks t...

Ulrike Guérot — European political scientist — Europe isn’t “the EU,” and the only way out of today’s crisis is to rebuild Europe’s republic‑spirit from culture upward—before war rebuilds it for us. In this uncut conversation we discuss: • The 1534 “Europa Regina” map and what it reveals about Europe’s lost identity • Why the EU’s nation‑state design broke the original citizen‑driven promise of Eu...

Robin Hanson — Social scientist & futurist — The universe looks empty for a reason, and the real “Great Filter” might be a quiet world government that stops humanity from ever expanding. In this uncut conversation we discuss: • The Great Filter explained simply—and why even a “small” filter ahead is terrifying • Why “quiet aliens” are possible, but big civilizations can’t stay hidden for long...

Dr. Tom O'Bryan — Doctor specializing in gluten-related disorders — Discover the hidden dangers of gluten and its inflammatory effects on health, as Dr. O'Bryan advocates for proactive healthcare and comprehensive testing.  In this uncut conversation he tells Enrico:   • Gluten is largely indigestible for everyone, often resulting in inflammation that targets the body's weakest area...

In this conversation, Dr. Ben Sessa discusses the definitions and impacts of psychedelics, particularly MDMA, in therapeutic settings. He emphasizes the importance of understanding the unique pharmacology of psychedelics and their potential to assist in mental health treatment, especially for those with trauma and addiction. The discussion also covers the risks associated with psychedelics, the da...

Avi Loeb — Researcher of Extraterrestrial Life — Join us as Avi Loeb explores the potential of discovering extraterrestrial life through interstellar objects like '3I/Atlas' and challenges our perceptions of existence and the universe. In this uncut conversation he tells Enrico: • There are only a few rare interstellar objects passing through our solar system each year, prompting discuss...

Carl Pullein — Productivity Expert — Discover how simplifying your task management can drastically enhance your productivity and reduce stress in daily life. In this uncut conversation he tells Enrico: • Explore the COD (Collect, Organize, Do) system and its role in effective task management. • Learn why managing based on available time, rather than task quantity, can lead to more accomplished day...

In this enlightening episode, Graham Harman explores the complexities of object-oriented ontology and its implications in navigating the challenges of contemporary technology, architecture, and the existential threats posed by AI. In this uncut conversation he tells Enrico: • Discover how the value of all objects, no matter their size, forms the core of object-oriented ontology. • Learn about the...

Maxim Korystov — Founder of Europe's leading high frequency trading company. In this comprehensive podcast, Max, a pioneer in high-frequency trading, demystifies the intricate world of algorithmic trading and its far-reaching impact on financial markets, particularly cryptocurrencies. In this uncut conversation he tells Enrico: • High-frequency trading leverages algorithmic execution, operati...

Serafim Korablev — Serial Entrepreneur and Founder of 21st.dev — Join us as Serafim shares his inspiring journey from a product manager to a self-taught coder and successful serial entrepreneur, emphasizing the transformative power of resilience and passion in business. In this uncut conversation, he tells Enrico: • He explores the motivational shift from the desire for wealth to finding joy in cr...

Maurice Willen — Multi-faceted strategist and advisor — Join us for a profound exploration of personal and professional growth, as Maurice shares transformative insights on designing a fulfilling life that prioritizes health, passion, and alignment with personal values. In this uncut conversation he tells Enrico: • Growth issues often stem from design problems rather than a lack of effort, emphasi...

Zoe Zaraisky — Certified Neuropsychologist, Specializing in Psychedelic Assisted Therapy and Breath Work. Dive into the transformative world of psychedelic therapy as Zoe unravels the complexities of mental health treatments that challenge traditional pharmaceutical approaches.  In this uncut conversation, she tells Enrico: • Understand the critical differences between therapeutic and recreational...

James Jenkins-Yates — founder of the world’s largest Airbnb management company — went from a flat in Pimlico to 6,000 listings, £160M in host revenue, a Series A… and then lost it all to layoffs and COVID. In this uncut conversation he tells Enrico: • Why quitting UBS at 24 was worth the chaos   • The £30 k Tube-ad gamble that exploded growth overnight   • Raising VC money vs. building profitably...

In this episode, we delve into the entrepreneurial journey of Greg Tkachenko. From his early days at ITMO University to co-founding a startup that Snapchat acquired for $166 million, Greg shares insights into building a tech company, navigating the startup ecosystem, and the pivotal moments leading to a successful exit. Tune in to hear about the challenges, strategies, and lessons learned from a f...