Endgame with Amanda Cassatt

What happens when machines become more economically valuable than humans? This episode dives into the real future of AI—not a sudden singularity, but a steady shift that’s redefining how we work, govern, and live. Amanda is joined by George Hotz to explore why humans still matter in an AI-driven world, how value creation—not credentials—will shape the future, and what happens when intellectual pro...

Curtis Yarvin—founder of Urbit, political philosopher and  blogger formerly known as Mencius Moldbug, the man who coined the term “red pill” is known for his influence on thinkers like Peter Thiel and JD Vance. In this episode, he offers a critical analysis of America’s political and economic landscape. He critiques the MAGA movement, exploring the limits of democracy and the rise of oligarchy, th...

Having access to a bank account is synonymous with human rights. Stani Kulechov is a pioneer in decentralized finance and blockchain technology. He is the Founder and CEO of Avara, the software development company behind DeFi protocol Aave, stablecoin GHO, SocialFi tech stack Lens Chain and Family, the Ethereum wallet.  In this episode, he joins Amanda to discuss the evolving dynamics between DeFi...

Is Ethereum staying true to its ideals? Ameen Soleimani—founder of SpankChain, summoner of MolochDAO, contributor to Tornado Cash, and now leading 0xbow—has spent years building tools that test the boundaries of decentralization and financial privacy. In this episode, he joins Amanda to explore Ethereum’s shifting values: what’s been preserved, what’s been sacrificed, and what’s at stake as the ne...

What if gaming guilds in the Philippines are already preparing for the future of work the rest of the world hasn’t seen coming? Gabby Dizon, Co-Founder of Yield Guild Games (YGG), shares how digital labor is evolving at the intersection of gaming, AI, and crypto. As automation threatens traditional jobs, guilds are becoming early experiments in agile, creative, globally distributed work. This epis...

The world is changing at an accelerating pace— Endgame is here to make sense of it. Hosted by Amanda Cassatt, founder of Serotonin, this podcast brings you conversations with the visionaries driving breakthrough technologies and shaping the future. Join Amanda as she unpacks the trends, innovations, and paradigm shifts defining our time. Where is this all going? Let’s figure it out together. Subsc...