eanCast: Weekly Neurology

Moderator: Elisa Canu (Milan, Italy) Guest: Cornelius Weiller (Freiburg, Germany) In this episode, Elisa Canu speaks with Cornelius Weiller about the neural architecture underlying language, concept formation, and the brain’s interaction with the environment. They discuss the role of dorsal, ventral, and semantic pathways, convergence hubs, and their relevance for understanding language processing...

Moderator: Gail Kinman (London, UK) Guest: Alice Accorroni (Geneva, Switzerland) In this episode, Alice Accorroni speaks with Gail Kinman about burnout in healthcare and the role of occupational health psychology in its prevention and management. They discuss the definition and recognition of burnout, key warning signs, and the importance of organisational factors, workplace culture, and leadershi...

Moderator: Cláudia Santos Silva (Lisbon, Portugal) Guest: Andrea Calvo (Turin, Italy) In this episode, Cláudia Santos Silva speaks with Andrea Calvo about the genetics of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). They discuss the shared genetic basis of these disorders, key disease-associated genes, and the role of genetic testing, counselling, and result interpretatio...

Moderator: Raffaele Dubbioso (Naples, Italy) Guest: Andrea Malaspina (London, UK) and Francesco Di Lorenzo (Rome, Italy) In this episode, Raffaele Dubbioso speaks with Andrea Malaspina and Francesco Di Lorenzo about the growing role of neurofilaments as biomarkers in amyotrophic lateral sclerosis and frontotemporal dementia. They discuss the biological basis and clinical interpretation of neurofil...

Moderator: Elisa Canu (Milan, Italy) Guest: Anna Gilioli (Milan, Italy) In this episode, Elisa Canu speaks with Anna Gilioli about social cognition impairment in amyotrophic lateral sclerosis (ALS). They discuss its clinical manifestations, underlying neurobiological mechanisms, and assessment approaches, highlighting the importance of early recognition and its implications for patient management,...

Moderator: Valentina Iuzzolino (Naples, Italy) Guest: Elka Stefanova (Belgrade, Serbia) and Mamede de Carvalho (Lisbon, Porugal) In this episode, Valentina Iuzzolino speaks with Elka Stefanova and Mamede de Carvalho about diagnostic challenges in amyotrophic lateral sclerosis and frontotemporal dementia. They discuss clinical heterogeneity, key differential diagnoses and red flags, the role of Gol...

Moderator: Raphael Wurm (Vienna, Austria) Guest: Roland Wiest (Bern, Switzerland) In this episode, Raphael Wurm speaks with Roland Wiest about how the AI revolution is set to reshape the clinical environment in neurology. They discuss the areas where augmentation and automation are likely to have the greatest impact, including neuroimaging, clinical workflows, and decision support, while exploring...

Moderator: Georg Starke (Munich, Germany) Guest: Giulia Di Rauso (New York, USA) In this episode, Georg Starke speaks with Giulia Di Rauso about trustworthiness and the use of artificial intelligence in neurological research and clinical practice. They discuss explainability, data quality, interpretability, and human oversight in AI systems, highlighting key considerations for responsible integrat...

Moderator: Maria Chiara Malaguti (Rovereto, Italy) Guest: Gary Leeming (Liverpool, UK) In this episode, Maria Chiara Malaguti and Gary Leeming discuss the evolving role of artificial intelligence in neurology. Aimed at clinical neurologists, the conversation explores how AI may support clinical practice, while also addressing its limitations, ethical implications, and the need for human oversight....

Moderator: Raphael Bernard-Valnet (Lausanne, Switzerland) Guest: Roland Wiest (Bern, Switzerland) and Monica Moroni (Trento, Italy) In this episode, Raphael Bernard-Valnet speaks with Roland Wiest and Monica Moroni about the fundamentals of artificial intelligence in clinical neurology and its practical implications for neurologists. They discuss key applications such as imaging analysis, diagnost...

Moderator: Kirsten R. Müller-Vahl (Hanover, Germany) Guest: Natalia Szejko (Warsaw, Poland) and Anna Dunalska (Warsaw, Poland) In this episode, Kirsten R. Müller-Vahl speaks with Natalia Szejko and Anna Dunalska about functional neurological disorders and the influence of social media. They discuss common clinical presentations, challenges in diagnosis based on positive signs, and the impact of on...

Moderator: Selma Aybek (Fribourg, Switzerland) Guests: Gabriela Gilmour (Calgary, Canada) and Katarzyna Śmiłowska (Sosnowiec, Poland) In this episode, Selma Aybek speaks with Gabriela Gilmour and Katarzyna Śmiłowska about the overlap between functional neurological disorders and movement disorders. They discuss key diagnostic principles based on positive clinical signs, mechanisms underlying co-oc...

Moderator: Primavera Spagnolo (Boston, MA) Guest: Natalia Szejko (Warsaw, Poland) and Anna Dunalska (Warsaw, Poland) In this episode, Primavera Spagnolo speaks with Natalia Szejko and Anna Dunalska about functional neurological disorders, focusing on the influence of biological sex and gender on their development and clinical presentation. They discuss diagnostic features, epidemiology and female...

Moderator: Veronica Cabreira (Porto, Portugal) Guest: Mark Edwards (London, UK) and Jon Stone (Edinburgh, UK) Functional Neurological Disorder (FND) remains one of the most common yet least adequately taught conditions in neurology training across Europe. In this episode, moderator Veronica Cabreira and expert guests Jon Stone and Mark Edwards reflect on historical and contemporary factors that co...

Moderator: Taras Voloshyn (Kyiv, Ukraine) Guests: Laavanya Damodaran (Birmingham, UK), Osman Malik (London, UK) In this episode, Taras Voloshyn speaks with Laavanya Damodaran and Osman Malik about autism spectrum disorder across the lifespan, with particular focus on the transition from childhood to adulthood. They discuss core diagnostic features, early clinical signs, evolving presentations in a...

Moderator: Francesco Germano (Genoa, Italy) Guest: Matteo Cataldi (Genoa, Italy) In this episode, Francesco Germano speaks with Matteo Cataldi about Guillain-Barré syndrome and other inflammatory neuropathies across the lifespan. They discuss key age-related differences in epidemiology, clinical presentation, diagnostic challenges, and management strategies in pediatric and adult patients, highlig...

Moderator: Natalia Szejko (Warsaw, Poland) Guests: Tammy Hedderly (London, UK), Alexander Münchau (Lübeck, Germany) In this episode, Natalia Szejko speaks with Tammy Hedderly and Alexander Münchau about the similarities and differences in movement disorders across the lifespan. They discuss the clinical evolution of tics and stereotypies from childhood to adulthood, the distinct diagnostic implica...

Moderator: Meagan Watson (Denver, USA) Guests: Pavlina Danhofer (Brno, Czech Republic), Natalia Szejko (Warsaw, Poland) In this episode, Meagan Watson speaks with Pavlína Danhofer and Natalia Szejko about whether functional neurological disorders (FNDs) present differently in children and adults. They discuss age-specific clinical features, comorbidities, developmental and family context, diagnost...

In this episode, Yıldız Değirmenci speaks with Julie Hall and Marit Ruitenberg about non-motor symptoms in Parkinson’s disease, focusing on anxiety and cognitive impairment. They examine their clinical profiles, early detection challenges including neuropsychological markers, interactions with motor manifestations, and implications for comprehensive assessment and individualized management in neur...

Moderator: João Durães (Coimbra, Portugal) Guests: Paola Giunti (London, UK), Lidia Sarro (Milan, Italy) In this episode, João Durães, Paola Giunti and Lidia Sarro provide a rigorous examination of the diagnostic and therapeutic landscape of treatable ataxias, focusing on rare variants. The discussion first delineates autoimmune etiologies, such as anti-GAD, paraneoplastic, and gluten-related synd...

Moderator: Olimpia Musumeci (Messina, Italy) Guests: Antonio Toscano (Messina, Italy), Marianne De Visser (Amsterdam, Netherlands) In this episode, Olimpia Musumeci speaks with Antonio Toscano and Marianne de Visser about hereditary, particularly metabolic, and acquired myopathies, especially idiopathic inflammatory myopathies amenable to treatment. They review advances in pathophysiology, diagnos...

Moderator: Emanuele D’amico (Foggia, Italy) Guest: Anna Bersano (Milan, Italy) In this episode, Emanuele D’Amico speaks with Anna Bersano about red flags for rare and potentially treatable cerebral small vessel diseases. They discuss how early onset, family history, multisystem involvement, and characteristic MRI patterns can help distinguish monogenic and metabolic forms from sporadic disease, fo...

Moderator: Piervito Lopriore (Pisa, Italy) Guests: Chiara La Morgia (Bologna, Italy), Michelangelo Mancuso (Pisa, Italy) In this episode, Piervito Lopriore discusses red flags for treatable mitochondrial diseases with Michelangelo Mancuso and Chiara La Morgia. They highlight the clinical heterogeneity of these disorders, key diagnostic clues in neurological practice, and selected conditions such a...

Moderator: Yildiz Degirmenci (Istanbul, Türkiye) Guest: Marit Ruitenberg (Leiden, Netherlands) In this episode, Yıldız Değirmenci speaks with Marit Ruitenberg about the relationship between cognition and movement in neurodegenerative disorders. They discuss evidence showing that conditions traditionally classified as motor or cognitive often involve impairments across both domains, with examples f...

Moderator: Gabriela Rusin (Kraków, Poland) Guest: Jakub Antczak (Kraków, Poland) In this episode, Gabriela Rusin speaks with Jakub Antczak about non-invasive neuromodulation in neurology. They outline the principles of transcranial magnetic stimulation and transcranial electrical stimulation, emphasizing their role in modulating brain plasticity in network-based neurological disorders. The discuss...