BMJ Group
DTB Podcast
The Drug and Therapeutics Bulletin (DTB) Podcast is your source for practical, independent, and evidence-based information on drugs, medication, and prescribing. Join the Editor-in-Chief and Deputy Editor of DTB each month as they discuss the key highlights of the latest issue. DTB - dtb.bmj.com - is published by BMJ Group, and offers rigorous, independent evaluations and practical advice on treatments and disease management for doctors, pharmacists, and healthcare professionals. Subscribe to the DTB Podcast and get the latest drug and therapeutic insights.* The purpose of this podcast is to e...
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Episodes
May 2018: Does pulmonary rehabilitation need more PR? 09.05.2018 11:59
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the evidence for pulmonary rehabilitation for COPD and highlight the need for more publicity for its benefits. Read the editorial here: http://dtb.bmj.com/content/56/5/49. The editors also review the evidence for safinamide for Parkinson’s disease (http://dtb.bmj.com/content/56/5/54), and d...
April 2018: STOMP - time to make more noise 11.04.2018 15:33
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a national campaign in England that is tackling the inappropriate use of antipsychotic and antidepressant medicines in people with learning or intellectual disability. Read the article: http://dtb.bmj.com/content/56/4/37. The editors also review the evidence for a once-daily triple inhaler...
March 2018: Do hypertension guidelines put the person first? 12.03.2018 11:16
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss some of the difficulties in implementing clinical guidelines for the management of elevated blood pressure and the potential impact of changes in the threshold for a diagnosis of hypertension (http://dtb.bmj.com/content/56/3/25). The editors also review the evidence for dupliumab for the tr...
February 2018: Clinical guidelines - more PDAs please 09.02.2018 13:10
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the importance of developing patient decision aids to support the implementation of clinical guidelines (http://dtb.bmj.com/content/56/2/13). The editors also review the evidence for cladribine for the treatment of highly active relapsing multiple sclerosis (http://dtb.bmj.com/content/56/2/...
January 2018: No alchemy for obesity 02.01.2018 12:37
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the importance of exercise, diet and behaviour modification in the management of obesity and consider the limitations of anti-obesity drugs. http://dtb.bmj.com/content/56/1/1 The editors also review the evidence for ▼patiromer, a cation exchange polymer, that has recently been marketed for...
December 2017: Shared care protocols – have they had their day? 04.12.2017 12:34
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the challenge of prescribing specialist drugs in primary care and highlight problems associated with the use of shared care protocols. http://dtb.bmj.com/content/55/12/133 The editors also review the evidence for an inhaler containing beclometasone, formoterol and glycopyrronium that has re...
November 2017: Prescribing in pregnancy - stop stopping and start planning 06.11.2017 14:29
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the challenges associated with prescribing for long-term conditions in women who are pregnant and raise concerns that medicines may be stopped inappropriately. Read the editorial here: http://dtb.bmj.com/content/55/11/121. The editors also review a combination product containing naltrexone...
October 2017: Flagging risk 09.10.2017 12:11
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the fragmented approach to communicating additional risk minimisation measures for medicines. Article available here: http://dtb.bmj.com/content/55/10/1. The editors also review the long-term safety of PPIs (http://dtb.bmj.com/content/55/10/117) and discuss the use of the live attenuated in...
September 2017: Vitamin D and adolescents: a forgotten ‘at risk’ group? 04.09.2017 11:20
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss vitamin D deficiency in teenagers and highlight the challenge of implementing national recommendations on vitamin D intake in young people. Full article here: http://dtb.bmj.com/content/55/9/1. The editors also review the management of scarlet fever (http://dtb.bmj.com/content/55/9/102.2) a...
August 2017: What price drugs online? 26.07.2017 12:02
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the supply of medicines from online primary care services (article here: http://dtb.bmj.com/content/55/8/85). The editors also review two recently licensed drugs: eluxadoline, a mixed opioid receptor agonist/antagonist for irritable bowel syndrome (http://dtb.bmj.com/content/55/8/90) and an...
July 2017: The good, the bad and the ugly 05.07.2017 13:38
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the role of Electroconvulsive Therapy (ECT) in the management of psychiatric disorders. Article here: http://dtb.bmj.com/content/55/7/1. The editors also discuss the use of liraglutide for obesity (related article here: http://dtb.bmj.com/content/55/7/78)and highlight some of the challenges...
June 2017: Turning the tide of high-dose inhaled corticosteroids 05.06.2017 11:18
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of high-dose inhaled corticosteroids in asthma and COPD. The editors also highlight some of the challenges associated with the management of superficial venous thrombosis of the leg and discuss the use of carbohydrate deficient transferrin as a biomarker for the assessment of chroni...
May 2017: Rational rationing in the NHS? 03.05.2017 13:04
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss attempts by the NHS in England to target £400m of prescribing expenditure that is reported to be wasted on a range of products that are considered to be of low value. Editorial available here: http://dtb.bmj.com/content/55/5/49 The editors also review the evidence for the use of off-label t...
April 2017: Prevention of type 2 diabetes - where do you draw the line? 28.03.2017 13:49
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a national initiative to identify and manage people at high risk of developing type 2 diabetes. Full article available here: http://dtb.bmj.com/content/55/4/37. The editors also review the evidence for an HRT product containing bazedoxifene and conjugated oestrogens (http://dtb.bmj.com/cont...
March 2017: Better PrEParation needed? 14.03.2017 12:58
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss some of the implications related to funding of pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV). They consider the Court of Appeal decision on funding and the role of clinical and health economic evaluations for preventative treatments. Full article available here: htt...
February 2017: Spironolactone - potion or poison? 06.02.2017 14:33
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the risk of hyperkalaemia associated with spironolactone in people with heart failure. They consider recent advice issued by the Medicines and Healthcare products Regulatory Agency and highlight the importance of regular monitoring of potassium and renal function. The editors also review th...
January 2017: Sore throat test and treat - a £34 million question? 09.01.2017 15:47
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a proposal from NHS England to introduce a sore throat test-and-treat service in community pharmacies. They review the evidence on the management of sore throat and examine the assumptions that underpin the proposed service. The editors also discuss pitolisant, a new drug for narcolepsy, an...
December 2016: Wise words on prescription of medicines and treatment decisions 21.11.2016 11:55
"Clarity begins at home". In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) start by remembering DTB's founding editor, Andrew Herxheimer's golden rules for prescribing. The DTB editors also discuss 'gliptins' in the management of diabetes and evidence from recent cardiovascular outcome studies, as well as, psychological interventions for eating disorders...
November 2016: Rubella immunisation. Check vaccination history 07.11.2016 11:20
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss changes to the rubella screening programme and the need to ensure that MMR vaccinations are up to date, especially in younger women born outside the UK. Read the full editorial here: http://dtb.bmj.com/content/54/11/121.full. The editors also discuss prescribing information sources (http://...
October 2016: the dangers of a quicker authorisation process for drugs 21.10.2016 9:16
Why should we worry about the new European Medicines Agency (EMA) pilot project to accelerate the approval of new drugs? James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the October issue Editorial, that looks at the pros and cons of this new trend both in the USA and Europe. Read the full article here: http://dtb.bmj.com/content/54/10/109.full. Also in this podc...
September 2016: Last orders for nalmefene in the management of alcohol dependence? 24.08.2016 12:38
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of nalmefene in the management of alcohol dependence. Although the drug has been approved for use in the NHS, DTB's editorial highlights limitations of the evidence supporting its use and discusses concerns raised by three groups of researchers. Currently, the NHS in England spends...
August 2016: Better guidelines. Capsaicin for diabetic neuropathy. Excipients in medicines 08.08.2016 18:08
In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the presentation of guidelines and ways of making them more accessible. Read the full editorial here: http://dtb.bmj.com/content/54/8/85.full There’s also an evaluation of the use of capsaicin for diabetic peripheral neuropathy. Article accessible here: http://dtb.bmj.com/content/54/8/90.fu...
July 2016: Where next for rationing medicines? Vitamins during pregnancy: a big marketing campaign? 07.07.2016 15:45
In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss proposals to stop the prescription of some medicines and foods in order to help manage the deficit in NHS budgets. Full article available here: http://dtb.bmj.com/content/early/2016/07/07/dtb.2016.7.0409.full. The podcast also includes a review of an article about the effects of the antidiabetic dr...
June 2016: Problems with botanicals; a new drug for heart failure; frailty and deprescribing 25.05.2016 19:43
In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of herbal products. They also develop the highlights of the articles: Articles: "Frailty, polypharmacy and deprescribing" and "Sacubitril valsartan for heart failure" Read all the articles featured here: dtb.bmj.com/content/54/6.toc
May 2016: supporting learning disabilities; new drugs for orthostatic hypotension and ADHD 09.05.2016 16:58
In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss health checks for young people with learning disabilities and review two recently licensed drugs - one for treating orthostatic hypotension and the other for managing ADHD in children and adolescents. Read all the articles featured here: dtb.bmj.com/content/54/5.toc
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